Stretch Intensity and the Inflammatory Response: A Paradigm Shift

Stretch Intensity and the Inflammatory Response: A Paradigm Shift

Author: Nikos C. Apostolopoulos

Publisher: Springer

Published: 2018-12-27

Total Pages: 239

ISBN-13: 3319968009

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In this manuscript, practitioners and students who are concerned with sports and rehabilitation medicine, kinesiology, as well as coaches and athletes, are introduced to numerous concepts, including mechanotransduction, inflammation, pro- and anti-inflammatory cytokines, calpains, the extracellular matrix, neutrophils and macrophages, and their relevance to stretching, particularly stretching intensity. Although the quantitative parameters of training, duration, and frequency are important, it is the qualitative criterion of intensity (“how much”) that the author suggests is ultimately of greater concern. Intensity, the rate and magnitude of force, may be responsible for the proper recovery, regeneration, and adaptation of the musculoskeletal tissues from training, competition, or rehabilitation from injuries. Research suggests that too much force results in the stimulation of an inflammatory response, one associated with a biochemical feedback emerging from a mechanical stimulus. The intent of this manuscript is twofold: to initiate the discussion of the importance of stretching intensity with regard to proper recovery, regeneration, and adaptation, and to suggest that researchers need to explore its potential role in addressing numerous inflammatory (RA) and non-inflammatory (OA, recurrent tendinitis etc.) musculoskeletal conditions as well.


Exercise Immunology

Exercise Immunology

Author: Michael Gleeson

Publisher: Routledge

Published: 2013-06-26

Total Pages: 581

ISBN-13: 113645585X

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Exercise immunology is an important, emerging sub-discipline within exercise physiology, concerned with the relationship between exercise, immune function and infection risk. This book offers a comprehensive, up-to-date and evidence-based introduction to exercise immunology, including the physiological and molecular mechanisms that determine immune function and the implications for health and performance in sport and everyday life. Written by a team of leading exercise physiologists, the book describes the characteristics of the immune system and how its components are organised to form an immune response. It explains the physiological basis of the relationship between stress, physical activity, immune function and infection risk, and identifies the ways in which exercise and nutrition interact with immune function in athletes and non-athletes. The book shows students how to evaluate the strengths and limitations of the evidence linking physical activity, immune system integrity and health, and explains why exercise is associated with anti-inflammatory effects that are potentially beneficial to long-term health. Every chapter includes useful features, such as clear summaries, definitions of key terms, discussions of seminal research studies and practical guidelines for athletes on ways to minimise infection risk, with additional learning resources available on a companion website. This is an essential textbook for any course on exercise immunology or advanced exercise physiology.


Biology of C Reactive Protein in Health and Disease

Biology of C Reactive Protein in Health and Disease

Author: Waliza Ansar

Publisher: Springer

Published: 2016-03-23

Total Pages: 324

ISBN-13: 8132226801

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This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.


Musculoskeletal Disorders and the Workplace

Musculoskeletal Disorders and the Workplace

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-05-24

Total Pages: 510

ISBN-13: 0309132991

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Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.


Fitness and Wellness in Canada

Fitness and Wellness in Canada

Author: Sarah J. Woodruff Atkinson

Publisher: Human Kinetics Publishers

Published: 2020

Total Pages: 417

ISBN-13: 1492589837

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"Developed specifically for the Canadian audience and written for first-year undergraduate students taking a general education fitness and wellness course, Fitness and Wellness in Canada: A Way of Life uses an engaging learning environment to provide students with the tools they need to become fit and well for life. In addition to providing students with an overview of the health-related components of fitness, Fitness and Wellness in Canada: A Way of Life teaches students how to embrace healthy eating and enjoy being physically active. Students learn how to establish fitness and wellness goals for now and throughout their lives. They learn how to manage stress, reduce the risk of metabolic syndrome and cancer, remain free from addiction, and develop a healthy sexuality"--


Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1999-05-13

Total Pages: 722

ISBN-13: 0309173183

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Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.


Indwelling Neural Implants

Indwelling Neural Implants

Author: William M. Reichert

Publisher: CRC Press

Published: 2007-12-17

Total Pages: 300

ISBN-13: 1420009303

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Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel


Borg's Perceived Exertion and Pain Scales

Borg's Perceived Exertion and Pain Scales

Author: Gunnar Borg

Publisher: Human Kinetics Publishers

Published: 1998

Total Pages: 104

ISBN-13: 9780880116237

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Dr. Gunnar Borg introduced the field of perceived exertion in the 1950s. His ratings of perceived exertion (RPE) scale is used worldwide by professionals in medicine, exercise physiology, psychology, cardiology, ergonomy, and sports. Now, Dr. Borg presents the definitive source for using the latest RPE and CR10 scales correctly. Borg's Perceived Exertion and Pain Scalesbegins with an overview and history to introduce readers to the field of perceived exertion. The book then covers principles of scaling and applications of both the RPE and the CR10 scaling methods. This user-friendly, informative, and readable text -discusses the fundamental bases of perceived exertion, -presents information on uses and misuses of the scales, and -provides guidance and direction on how and when to measure subjective somatic symptoms. A special appendix in the back of the book includes tear-out cards containing three RPE scales and three CR10 scales. A scale and instructions for how the scale is used are printed on each two-sided card. Borg's Perceived Exertion and Pain Scalesis the complete theoretical and methodological guide to the field of human perception.


Oxford Textbook of Musculoskeletal Medicine

Oxford Textbook of Musculoskeletal Medicine

Author: Michael Hutson

Publisher: Oxford University Press

Published: 2016

Total Pages: 759

ISBN-13: 0199674108

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This all-in-one companion to the field of musculoskeletal medicine describes basic concepts and offers practical guidelines for diagnosis and treatment, and contains models of care which assist understanding of basic concepts.


Brain Neurotrauma

Brain Neurotrauma

Author: Firas H. Kobeissy

Publisher: CRC Press

Published: 2015-02-25

Total Pages: 718

ISBN-13: 1466565993

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With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.