Pyrantel Parasiticide Therapy in Humans and Domestic Animals
Pyrantel Parasiticide Therapy in Humans and Domestic Animals

Author: Alan A Marchiondo

Publisher: Academic Press

Published: 2016-06-03

Total Pages: 0

ISBN-13: 9780128014493

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Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidines and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970's to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years.

Medicinal Natural Products: A Disease-Focused Approach
Medicinal Natural Products: A Disease-Focused Approach

Author:

Publisher: Academic Press

Published: 2020-09-21

Total Pages: 532

ISBN-13: 0128210206

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Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition, with chapters in this new release covering Medicinal Natural Products – An Introduction, Anticancer Natural Products, Antimicrobial Natural Products, Antimalarial and Antiparasitic Natural Products, Anti-inflammatory Natural Products, Neuroprotective Natural Products, Hepatoprotective Natural Products, Nephroprotective Natural Products, Cancer Chemopreventive Natural Products, Antipsoriatic Natural Products, Medicinal Natural Products in Osteoporosis, Antidiabetic Natural Products, Anti-obesity Natural Products, and much more. - Presents a disease-focused perspective - Includes the latest on the medicinal chemistry of natural products - Covers natural products in drug delivery

Parasiticide Screening
Parasiticide Screening

Author: Alan A. Marchiondo

Publisher: Academic Press

Published: 2019-06-08

Total Pages: 724

ISBN-13: 0128165782

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Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods, Volume Two presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds. - Addresses current issues of resistance, along with combination uses for resistant parasites - Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds - Includes a discussion on screening methods in combination therapies - Provides cutting-edge material for an evolving area of scientific discussion - Includes in vitro and in vivo screens and parasite maintenance and culture methods