Modern Methods of Steroid Analysis
Modern Methods of Steroid Analysis

Author: Erich Heftmann

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 558

ISBN-13: 0323146449

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Modern Methods of Steroid Analysis reviews modern methods of steroid analysis such as liquid column chromatography, mass spectrometry, and gas chromatography. Topics covered include qualitative and quantitative analysis of plant sterols by gas-liquid chromatography; Raman spectroscopy of steroids; nuclear magnetic resonance; and applications of lanthanide shift reagents. A computerized method for rapid comparison and retrieval of infrared spectral data is also described. This volume is comprised of 22 chapters and begins with an analysis of hormonal steroids using liquid column chromatography, followed by a discussion on the separation of insect molting hormones using high-pressure liquid chromatography. The reader is methodically introduced to the application of gradient elution and thin-layer chromatography to the analysis of corticosteroids and 17-ketosteroids, as well as some aspects of mass spectrometry in steroid analysis. Subsequent chapters explore other methods such as optical rotatory dispersion and circular dichroism, along with radioisotope techniques. In particular, the radioimmunoassay of plasma steroid hormones and plasma aldosterone is considered. This book should be of interest to biochemists.

Steroid Analysis
Steroid Analysis

Author: Hugh L. J. Makin

Publisher: Springer Science & Business Media

Published: 2010-06-04

Total Pages: 1240

ISBN-13: 1402097751

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The second edition of this handbook concentrates on the analysis of steroids in biological fluids. It offers analysis of low levels of steroid analytes in biological fluids. This new edition also provides an extra chapter on pharmaceutical aspects of steroid analysis. Coverage details spectroscopic and other methods, including UV and IR absorption spectroscopy, NMR spectroscopy, mass spectrometry, X-ray diffraction, chromatography and immunoassay of steroids.

Textbook on Scar Management
Textbook on Scar Management

Author: Luc Téot

Publisher: Springer Nature

Published: 2020-12-07

Total Pages: 553

ISBN-13: 3030447669

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This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners

Glucocorticoid-induced Osteoporosis
Glucocorticoid-induced Osteoporosis

Author: Andrea Giustina

Publisher: Karger Medical and Scientific Publishers

Published: 2002

Total Pages: 213

ISBN-13: 3805572964

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Osteoporosis is one of the most clinically relevant disabling chronic disease encountered in clinical practice. A common cause of osteoporosis is glucocorticoid excess, as glucocorticoids may increase bone resorption, inhibit bone formation, have indirect actions on bone by decreasing intestinal calcium absorption and induce hypercalciuria. This book presents a comprehensive overview of the effects of glucocorticoids on bone metabolism and structure and on the diagnosis and treatment of glucocorticoid-induced osteoporosis. It aims at providing updated information on the pathogenesis, diagnosis and treatment of this often dramatic complication of glucocorticoid excess. Being one of the few publications completely devoted to glucocorticoid-induced osteoporosis it will heighten the awareness of specialists who prescribe glucocorticoids of the clinical relevance of this treatment complication. 'Glucocorticoid-Induced Osteoporosis' is addressed to clinical experts as well as to general practitioners who will both benefit from the comprehensive and integrative view of the management of patients exposed to glucocorticoids.

Dynamics of Brain Edema
Dynamics of Brain Edema

Author: Hanna M. Pappius

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 456

ISBN-13: 3642665241

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A workshop on Dynamic Aspects of Cerebral Edema was organized to pro vide an opport~nitY,for interdisciplinary and detailed consideration of this subject, so crucial in neurology and neurosurgery. The previ ous workshops were held in Vienna in 1965 and in Mainz in 1972. In the meantime, our ideas on mechanisms of resolution of cerebral edema had been changing drastically. Controversy had arisen regarding the role of biogenic amines in the development of edema. Active work in several centers had indicated the possibility of a reversible compo nent in edematous changes associated with ischemia, the control of which could be of therapeutic significance in the problem of stroke. It was felt that a thorough discussion, at this time, by those involv ed in these various studies should help to resolve the controversies, to crystallize the implications of the new findings, and to evaluate their application for patient care. In preparing the proceedings for publication we have edited the manu scripts and selected the discussions with an aim to highlight new find ings, to make this volume readable, and to eliminate duplication. We gratefully acknowledge financial support from the institutions and organizations previously listed. Many individuals contributed to the success of the workshop and the preparation of the proceedings for publication. Doctors J.B. Brierley, I. Klatzo, H.J. Reulen, and A.G.

The Hypothalamus-Pituitary-Adrenal Axis
The Hypothalamus-Pituitary-Adrenal Axis

Author:

Publisher: Elsevier

Published: 2008-09-12

Total Pages: 413

ISBN-13: 0080559360

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The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later

Steroid-protein Interactions
Steroid-protein Interactions

Author: Ulrich Westphal

Publisher: Springer

Published: 1971

Total Pages: 592

ISBN-13:

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This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.

Diagnosis and Management of Ovarian Disorders
Diagnosis and Management of Ovarian Disorders

Author: Albert Altchek

Publisher: Elsevier

Published: 2003-09-04

Total Pages: 595

ISBN-13: 008049451X

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This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine