Spotlight on Potassium Channels and Their Modulation
Author: Edward Carmeliet
Publisher:
Published: 1992
Total Pages: 151
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: Edward Carmeliet
Publisher:
Published: 1992
Total Pages: 151
ISBN-13:
DOWNLOAD EBOOKAuthor: John M Evans
Publisher: CRC Press
Published: 1996-04-01
Total Pages: 449
ISBN-13: 1482272849
DOWNLOAD EBOOKPotassium ions K+ ions are vital in physiological processes, particularly with regard to the cardiovascular system. Modulators influence the channels through which these ions flow and the research into modulator drugs of these channels is the subject of rapidly-advancing research. This work is intended to be of use as a tool for those working in th
Author: Valentin K. Gribkoff
Publisher: John Wiley & Sons
Published: 2008-12-09
Total Pages: 505
ISBN-13: 0470429895
DOWNLOAD EBOOKThis book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.
Author: Hailin Zhang
Publisher:
Published: 1995
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: Jonathan D. Lippiat
Publisher: Humana Press
Published: 2010-11-19
Total Pages: 0
ISBN-13: 9781617379406
DOWNLOAD EBOOKDue to the importance of potassium channels in cellular function, researchers have been challenged to develop tools and experimental procedures to probe the function and identify chemicals that modulate the behaviour of this super-family of ion channels. In Potassium Channels: Methods and Protocols, experts in the field present a range of experimental approaches that have been developed to investigate potassium channel structure, function, pharmacology, cell biology, gene expression, and their role in disease. Many of these techniques study potassium channels as cellular proteins as well as the resultant membrane biophysics. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters contain brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Potassium Channels: Methods and Protocols provides a wide range of approaches in order to aid current research projects and inspire new investigations.
Author: Hugh Malcolm Chapman
Publisher:
Published: 1997
Total Pages: 316
ISBN-13:
DOWNLOAD EBOOKAuthor: Sophia Shihui Kuo
Publisher:
Published: 1993
Total Pages: 342
ISBN-13:
DOWNLOAD EBOOKAuthor: Alex John Caley
Publisher:
Published: 2007
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: F. Lehmann-Horn
Publisher: Elsevier
Published: 2000-11-16
Total Pages: 383
ISBN-13: 0080528856
DOWNLOAD EBOOKThis book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, cardiology, and nephrology requiring a wide and interdisciplinary readership. Interesting parallels in pathogenetic mechanisms of disease are especially emphasized to interest even highly specialized readers in entities outside of their fields. Each author has written an objective overview of his or her particular subject in a way that should allow the reader within a short period of time to obtain a comprehensive picture of the present state of art.
Author: Hiromu Yawo
Publisher: Springer Nature
Published: 2021-01-05
Total Pages: 648
ISBN-13: 9811587639
DOWNLOAD EBOOKThis book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.