Should Hormesis Be the Default Model in Risk Assessment?
Author: Edward J. Calabrese
Publisher: DIANE Publishing
Published: 2008-10
Total Pages: 32
ISBN-13: 1437904610
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Hormesis
Author: Mark P. Mattson
Publisher: Springer Science & Business Media
Published: 2009-12-01
Total Pages: 219
ISBN-13: 1607614952
DOWNLOAD EBOOKHormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.
Hormesis in Health and Disease
Author: Suresh I. S. Rattan
Publisher: CRC Press
Published: 2014-05-16
Total Pages: 386
ISBN-13: 1482205459
DOWNLOAD EBOOKSome mild stresses have positive effects on survival and aging as shown in animal models. There is also a large body of research that demonstrates these hormetic effects on aging, health, and resistance to severe stresses and diseases in human beings. However, the data are dispersed in the literature and are not always interpreted as hormetic effects. Hormesis in Health and Disease reviews the evidence for hormesis in humans as achieved through a variety of stresses or stimuli, and discusses mechanisms of hormesis and its ethical and legal issues. Divided into four sections, this book presents the current state of research, including questions, debates, doubts, and controversies in hormesis. Section I covers the history and terminology of hormesis, describing its main features and providing necessary background information. Section II shows that hormetic effects can be caused by various stresses—including physical exercise, nutritional components, fasting, micronutrients, irradiation, heat, ischemia, and mental challenge—and can be observed both in organs and at the organism level. Section III reviews possible mechanisms of hormesis that have been elucidated at this point. Section IV discusses the wider consequences hormesis may have for everyone. This book demonstrates that health beneficial hormetic effects do exist in human beings. It offers information to inspire key players to initiate new strategies to elucidate the strengths and limits of the dual nature of stress.
The Science of Hormesis in Health and Longevity
Author: Suresh Rattan
Publisher: Academic Press
Published: 2018-10-23
Total Pages: 327
ISBN-13: 0128142545
DOWNLOAD EBOOKThe Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work. - Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and aging - Includes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventions - Offers a clear understanding of hormesis' underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more
Radiation Hormesis
Author: T. D. Luckey
Publisher: CRC Press
Published: 1991-09-20
Total Pages: 320
ISBN-13: 9780849361593
DOWNLOAD EBOOKRadiation Hormesis presents the only critical review of the effects of whole-body exposure to low doses of ionizing radiation in animals. This is a "must read" book for radiobiologists, health-conscious individuals, and serious environmentalists. Topics discussed include our radiation environment, radiation hormesis in cancer mortality, growth and development, reproduction and mutation, immunity, and cancer. Data is presented that indicates that low doses of ionizing radiation may actually be beneficial to human health. This information could invalidate the "zero thesis" and linear models used by most regulatory agencies. The implications regarding eliminating linear models and accepting radiation hormesis are also discussed.
Hormesis and the Law: Toxic Torts
Author: Edward J. Calabrese
Publisher: DIANE Publishing
Published: 2008-06
Total Pages: 20
ISBN-13: 1437902235
DOWNLOAD EBOOKEncyclopedia of Aquatic Ecotoxicology
Author: Jean-Francois Férard
Publisher: Springer
Published: 2013-06-14
Total Pages: 0
ISBN-13: 9789400750401
DOWNLOAD EBOOKWith its 104 chapters, this Encyclopedia of aquatic ecotoxicology reveals the diversity of issues, problems and challenges that have faced, and are facing today, receiving environments. It also indicates ways by which tools, strategies and future investigations can contribute to correct, minimize, solve and prevent water quality degradation. Structured homogeneously, the chapters convey salient information on historical background, features, characteristics, uses and/or applications of treated topics, often complemented by illustrations and case studies, as well as by conclusions and prospects. This work is most suitable for teaching purposes. Academics, for example, could literally deliver comprehensive lectures to students simply based on chapter outlines and contents. Meet the Authors of the Encyclopedia! Check out 'Meet the Authors' under ADDITIONAL INFORMATION (Right menu).
Biological Concepts and Techniques in Toxicology
Author: Jim E. Riviere
Publisher: CRC Press
Published: 2006-03-06
Total Pages: 412
ISBN-13: 1420018442
DOWNLOAD EBOOKHighlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicol
Cancer Risk Assessment
Author: Ching-Hung Hsu
Publisher: John Wiley & Sons
Published: 2010-12-08
Total Pages: 727
ISBN-13: 1118035127
DOWNLOAD EBOOKWith a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.
Explaining Health Across the Sciences
Author: Jonathan Sholl
Publisher: Springer Nature
Published: 2020-08-28
Total Pages: 551
ISBN-13: 3030526631
DOWNLOAD EBOOKThis edited volume aims to better understand the multifaceted phenomenon we call health. Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. The book is divided into three parts and a conclusion: the first part explains health from within specific disciplines, the second part explores health from the perspective of a bodily part, system, function, or even the environment in which organisms live, and the final part looks at more clinical or practical perspectives. It thereby gathers, across 30 chapters, diverse perspectives from the broad fields of evolutionary and systems biology, immunology, and biogerontology, more specific areas such as odontology, cardiology, neurology, and public health, as well as philosophical reflections on mental health, sexuality, authenticity and medical theories. The overarching aim is to inform, inspire and encourage intellectuals from various disciplines to assess whether explanations in these disparate fields and across biological levels can be sufficiently systematized and unified to clarify the complexity of health. It will be particularly useful for medical graduates, philosophy graduates and research professionals in the life sciences and general medicine, as well as for upper-level graduate philosophy of science students.
