Sex Differences in Physiology
Sex Differences in Physiology

Author: Gretchen Neigh

Publisher: Academic Press

Published: 2016-05-10

Total Pages: 236

ISBN-13: 0128026081

DOWNLOAD EBOOK

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Sex Differences in Cardiovascular Physiology and Pathophysiology
Sex Differences in Cardiovascular Physiology and Pathophysiology

Author: Babbette LaMarca

Publisher: Academic Press

Published: 2019-04-11

Total Pages: 392

ISBN-13: 0128131977

DOWNLOAD EBOOK

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

Exploring the Biological Contributions to Human Health
Exploring the Biological Contributions to Human Health

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-07-02

Total Pages: 287

ISBN-13: 0309132975

DOWNLOAD EBOOK

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Principles of Sex-based Differences in Physiology
Principles of Sex-based Differences in Physiology

Author: Virginia L. Miller

Publisher: Gulf Professional Publishing

Published: 2004

Total Pages: 356

ISBN-13: 9780444514974

DOWNLOAD EBOOK

Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.

Sex Differences in the Central Nervous System
Sex Differences in the Central Nervous System

Author: Rebecca M. Shansky

Publisher: Academic Press

Published: 2015-09-14

Total Pages: 430

ISBN-13: 0128021985

DOWNLOAD EBOOK

Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included. Details how sex hormones have widespread effects on the nervous system and influence the way males and females function Assists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influences Includes discussions of research in both animal models and human patient populations, and at various developmental stages Features revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available

Advances in Molecular and Cell Biology
Advances in Molecular and Cell Biology

Author: Edward Bittar

Publisher: Elsevier Science

Published: 1992

Total Pages: 270

ISBN-13: 9781559382090

DOWNLOAD EBOOK

The fourth volume of the Advances in Molecular and Cell Biology series. Cell biology is a rapidly-developing discipline, bringing together many separate biological sciences. The interrelations of cell structure and function at molecular and subcellular levels are the central theme of the series.

Pancreatic Islet Biology
Pancreatic Islet Biology

Author: Anandwardhan A. Hardikar

Publisher: Springer

Published: 2016-10-25

Total Pages: 332

ISBN-13: 3319453076

DOWNLOAD EBOOK

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

Handbook of Gender Research in Psychology
Handbook of Gender Research in Psychology

Author: Joan C. Chrisler

Publisher: Springer Science & Business Media

Published: 2010-03-12

Total Pages: 715

ISBN-13: 144191465X

DOWNLOAD EBOOK

Donald R. McCreary and Joan C. Chrisler The Development of Gender Studies in Psychology Studies of sex differences are as old as the ?eld of psychology, and they have been conducted in every sub?eld of the discipline. There are probably many reasons for the popularity of these studies, but three reasons seem to be most prominent. First, social psychological studies of person perception show that sex is especially salient in social groups. It is the ?rst thing people notice about others, and it is one of the things we remember best (Fiske, Haslam, & Fiske, 1991; Stangor, Lynch, Duan, & Glass, 1992). For example, people may not remember who uttered a witty remark, but they are likely to remember whether the quip came from a woman or a man. Second, many people hold ?rm beliefs that aspects of physiology suit men and women for particular social roles. Men’s greater upper body strength makes them better candidates for manual labor, and their greater height gives the impression that they would make good leaders (i. e. , people we look up to). Women’s reproductive capacity and the caretaking tasks (e. g. , breastfeeding, baby minding) that accompany it make them seem suitable for other roles that require gentleness and nurturance. Third, the logic that underlies hypothesis testing in the sciences is focused on difference. Researchers design their studies with the hope that they can reject the null hypothesis that experimental groups do not differ.

Sex Differences in Heart Disease
Sex Differences in Heart Disease

Author: Bohuslav Ostadal

Publisher: Springer Nature

Published: 2020-11-15

Total Pages: 284

ISBN-13: 3030586774

DOWNLOAD EBOOK

Cardiovascular diseases are the leading cause of mortality in men and women. Unfortunately, women have traditionally been excluded from clinical trials, and female animals have been used less or sex was not reported in basic research studies. Until recently, consideration of both sexes was not required in clinical and preclinical studies focusing on cardiovascular diseases. However, the number of clinical and experimental papers dealing with sex differences and heart disease significantly increases during the last years. This trend is obviously the result of at least two facts: the number of examples of different behavior of the male and female heart under physiological and pathological conditions is steadily increasing and there were controversial reports on the beneficial and adverse effect of hormonal replacement therapy. Detailed molecular and cellular mechanisms of these differences are still unknown but one is clear already today: sex differences are so important that they should be considered by the selection of optimum diagnostic and therapeutic procedures in clinical practice. The book presents 16 manuscripts on sex differences of heart disease, as developed by several investigators; the volume is organized in four parts. Part I, dealing with sex differences in cardiac ischemic injury, includes 5 chapters on experimental aspects of cardiac ischemia/reperfusion injury, the role of testosterone, and clinical aspects of ischemic heart disease. Part II is devoted to sex differences in heart failure and includes four chapters. Discussion in this part of the book is centered around the sex differences in heart failure due to volume overload. Part III of this volume includes four papers on risk factors of cardiovascular diseases, namely hypertension and obesity, and, finally, three chapters in part IV deal with sex differences of cardiac mitochondria under different pathological conditions. We believe this book will be very useful for cardiovascular scientists, graduate students, postdoctoral fellows and other health professionals.

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Author: Franck Mauvais-Jarvis

Publisher: Springer

Published: 2017-12-08

Total Pages: 630

ISBN-13: 3319701789

DOWNLOAD EBOOK

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.