Next-Generation Sequencing Data Analysis

Next-Generation Sequencing Data Analysis

Author: Xinkun Wang

Publisher: CRC Press

Published: 2016-04-06

Total Pages: 252

ISBN-13: 1482217899

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A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi


Next-generation DNA Sequencing Informatics

Next-generation DNA Sequencing Informatics

Author: Stuart M. Brown

Publisher:

Published: 2015

Total Pages: 0

ISBN-13: 9781621821236

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"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"


Next-Generation Genome Sequencing

Next-Generation Genome Sequencing

Author: Michal Janitz

Publisher: John Wiley & Sons

Published: 2011-08-24

Total Pages: 281

ISBN-13: 3527644733

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Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.


Bioinformatics for High Throughput Sequencing

Bioinformatics for High Throughput Sequencing

Author: Naiara Rodríguez-Ezpeleta

Publisher: Springer Science & Business Media

Published: 2011-10-26

Total Pages: 258

ISBN-13: 1461407826

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Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.


Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome

Author: National Research Council

Publisher: National Academies Press

Published: 1988-01-01

Total Pages: 128

ISBN-13: 0309038405

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.


Nanopore Sequencing: An Introduction

Nanopore Sequencing: An Introduction

Author: Daniel Branton

Publisher: World Scientific

Published: 2019-04-05

Total Pages: 217

ISBN-13: 9813270624

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This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.


Clinical Applications for Next-Generation Sequencing

Clinical Applications for Next-Generation Sequencing

Author: Urszula Demkow

Publisher: Academic Press

Published: 2015-09-10

Total Pages: 336

ISBN-13: 0128018410

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Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies


Yoga Sequencing

Yoga Sequencing

Author: Mark Stephens

Publisher: North Atlantic Books

Published: 2012-09-18

Total Pages: 529

ISBN-13: 1583944974

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The yoga teacher’s guide to planning and sequencing yoga classes—with over 2,000 instructional photos and 67 yoga pose sequences for students of all skill levels. Also features additional resources, including yoga class planning worksheets, comprehensive glossaries, and much more! Addressing one of the most popular topics in the yoga profession, this book offers 67 model sequences of yoga poses (asanas) that cover the broad range of yoga student experience. Inside, established and aspiring yoga teachers will find: • Over 2,000 instructional photos and guide to over 150 yoga asanas • Multiple sequences for beginning, intermediate, and advanced students • Yoga sequences for kids, teens, seniors, and women across their life cycle • Yoga classes designed for relieving depression and anxiety • Sequences for each of the major chakras and ayurvedic constitutions • Guidance for teaching breathing (pranayama) and meditation techniques • Glossary of terms and alphabetical asana index with thumbnail photographs • Yoga class planning worksheets • Representative sequences from several popular styles of hatha yoga • And many more resources for further reading! Drawing on ancient yoga philosophy and contemporary insights into functional anatomy, biomechanics, and kinesiology, Yoga Sequencing is the ultimate guide teachers looking to bring the transformative power of yoga into their practice and classes.


Next Generation Sequencing and Sequence Assembly

Next Generation Sequencing and Sequence Assembly

Author: Ali Masoudi-Nejad

Publisher: Springer Science & Business Media

Published: 2013-07-09

Total Pages: 92

ISBN-13: 1461477263

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The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly. ​