Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Author: Steven Nolan

Publisher: Thieme

Published: 2017-06-14

Total Pages: 807

ISBN-13: 3132013315

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The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 2

Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 2

Author: Steven Nolan

Publisher: Thieme

Published: 2017-06-14

Total Pages: 816

ISBN-13: 3132414034

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The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


N-heterocyclic Carbenes in Catalytic Organic Synthesis

N-heterocyclic Carbenes in Catalytic Organic Synthesis

Author: Steven Nolan

Publisher: Thieme Chemistry

Published: 2017

Total Pages: 0

ISBN-13: 9783132012912

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The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


N-Heterocyclic Carbenes in Catalytic Organic Synthesis, Workbench Edition

N-Heterocyclic Carbenes in Catalytic Organic Synthesis, Workbench Edition

Author: Steven Nolan

Publisher: Thieme Chemistry

Published: 2017-06-14

Total Pages: 0

ISBN-13: 9783132414303

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These SOS volumes provide a user's guide to NHC chemistry and catalysis, thus facilitating the introduction of NHCs to novices and also helping to expand the repertoire of synthetic tools available to the more-advanced researcher, enabling the design of new catalysts and reactions. Volume 1 provides a detailed introduction to NHCs, with discussion of their architectures and steric and electronic properties. The synthesis of NHC precursors, NHCs themselves, and metal-NHC complexes is described. The use of NHCs in cross-coupling chemistry (carbon-carbon and carbon-heteroatom bond formation), C-H bond functionalization, and addition reactions to carbon-carbon multiple bonds is reviewed. Volume 2 covers the use of NHCs in the various types of metathesis reaction, polymerization, cyclization reactions, oxidation reactions, and carbonylation/carboxylation reactions. The use of NHCs in asymmetric transition-metal catalysis is highlighted, as are recyclable systems (biphasic, covalently immobilized, and ionically tagged systems), NHCs in flow chemistry, and recent advances in the use of NHCs in organocatalysis.


N-Heterocyclic Carbenes in Synthesis

N-Heterocyclic Carbenes in Synthesis

Author: Steven P. Nolan

Publisher: John Wiley & Sons

Published: 2006-12-13

Total Pages: 319

ISBN-13: 3527609407

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This first handbook to focus solely on the application of N-heterocyclic carbenes in synthesis covers metathesis, organocatalysis, oxidation and asymmetric reactions, along with experimental procedures. Written by leading international experts this is a valuable and practical source for every organic chemist.


N-Heterocyclic Carbenes in Organocatalysis

N-Heterocyclic Carbenes in Organocatalysis

Author: Akkattu T. Biju

Publisher: John Wiley & Sons

Published: 2019-05-06

Total Pages: 436

ISBN-13: 3527343105

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Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.


N-Heterocyclic Carbenes

N-Heterocyclic Carbenes

Author: Steven P. Nolan

Publisher: John Wiley & Sons

Published: 2014-07-07

Total Pages: 690

ISBN-13: 3527671242

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This comprehensive reference and handbook covers in depth all major aspects of the use of N-heterocyclic carbene-complexes in organic synthesis: from the theoretical background to characterization, and from cross-coupling reactions to olefin metathesis. Edited by a leader and experienced scientist in the field of homogeneous catalysis and use of NHCs, this is an essential tool for every academic and industrial synthetic chemist.