Sarcoplasmic Reticulum
Sarcoplasmic Reticulum

Author: Rigers Bakiu

Publisher:

Published: 2015

Total Pages: 171

ISBN-13: 9781634828512

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Muscle cells, including cardiomyocytes, contain a specialized smooth endoplasmic reticulum (ER), sarcoplasmic reticulum (SR) calcium ions (Ca2+) release and reuptake by the sarcoplasmic reticulum trigger the contraction and relaxation of the myofibrils, respectively. This book examines the control and modulation of the SR and how this may vary among skeletal and cardiac muscle without bypassing the smooth muscle. It presents new and exciting work in this area and identifies promising new research directions. Furthermore, it considers the advances in this relatively unexplored field, offering new insights into the role of SR communication with other organelles and the new concepts about ER stress. Generally, this scientific book brings together contributions from key workers--both in basic and clinical sciences-- whose studies range from physiological to pathological and molecular to whole animal. In this book, the authors provide insights into the evolution of SR design and function.

Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle
Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle

Author: George B. Frank

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 450

ISBN-13: 1461533627

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The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad.

Biochemistry of Smooth Muscle Contraction
Biochemistry of Smooth Muscle Contraction

Author: Michael Barany

Publisher: Elsevier

Published: 1996-01-04

Total Pages: 455

ISBN-13: 0080527892

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This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.

Structure and Function of Sarcoplasmic Reticulum
Structure and Function of Sarcoplasmic Reticulum

Author: Sidney Fleischer

Publisher:

Published: 1985

Total Pages: 648

ISBN-13:

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Structure and Function of Sarcoplasmic Reticulum is a compendium of papers from an International Conference on Sarcoplasmic Reticulum held in Japan on November 1-4, 1982. Section I is a review of sarcoplasmic reticulum including the ""discovery"" of the relaxing factor, the calcium binding of relaxing factor, as well as phosphate transfer and calcium transport coupling. Section II involves the chemistry and structure of the calcium pump protein in sarcoplasmic reticulum. One paper describes the role of protein-lipid interactions in the organization and function of biomembranes. Section III con ...

Functional Ultrastructure
Functional Ultrastructure

Author: Margit Pavelka

Publisher: Springer Science & Business Media

Published: 2010-07-16

Total Pages: 366

ISBN-13: 3211993908

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The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.

Mechanisms of Vascular Disease
Mechanisms of Vascular Disease

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Disorders of Voluntary Muscle
Disorders of Voluntary Muscle

Author: George Karpati

Publisher: Cambridge University Press

Published: 2001-07-12

Total Pages: 800

ISBN-13: 9780521650625

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Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Smith's Anesthesia for Infants and Children E-Book
Smith's Anesthesia for Infants and Children E-Book

Author: Peter J. Davis

Publisher: Elsevier Health Sciences

Published: 2016-10-15

Total Pages: 1829

ISBN-13: 0323388698

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Now thoroughly up to date with new chapters, Smith’s Anesthesia for Infants and Children, 9th Edition, by Drs. Peter Davis and Franklyn Cladis, covers the information you need to provide effective perioperative care for any type of pediatric surgery. Leading experts in pediatric anesthesia bring you up to date with every aspect of both basic science and clinical practice, helping you incorporate the latest clinical guidelines and innovations in your practice. Quick-reference appendices: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Outstanding visual guidance in full color throughout the book. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. More than 100 video demonstrations, including new regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. Table of Contents has been reorganized and new chapters added on statistics, sedation, pediatric obesity, and cardiac critical care pediatrics. A new chapter on regional anesthesia for pediatrics, including video and ultrasound demonstrations online. A new chapter on dermatology, specifically for the anesthesiologist, with more than 100 photos. A new chapter on medical missions to third-world countries, including what you should know before you go. A new Questions chapter provides opportunities for self-assessment. New coverage includes cardiac anesthesia for congenital heart disease, anesthesia outside the operating room, and a new neonatology primer for the pediatric anesthesiologist.

Neuromuscular Function and Disorders
Neuromuscular Function and Disorders

Author: Alan J. McComas

Publisher: Butterworth-Heinemann

Published: 1977

Total Pages: 382

ISBN-13:

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Neuromuscular Function and Disorders focuses on the various processes underlying disordered neuromuscular function. Topics covered include the nature of membrane defects in myotonia and familial periodic paralysis; the disorder of neuromuscular transmission responsible for myasthenia gravis and the various pseudo-myasthenic syndromes; and the disorders of Schwann cell function which cause demyelination. This book is comprised of 28 chapters divided into two sections and begins with a discussion on the normal anatomy and physiology of peripheral nerve and muscle. Included in the first section a ...