The Use of Drugs in Food Animals
The Use of Drugs in Food Animals

Author: National Research Council

Publisher: National Academies Press

Published: 1999-01-12

Total Pages: 276

ISBN-13: 0309175771

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The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

Residue Evaluation of Certain Veterinary Drugs
Residue Evaluation of Certain Veterinary Drugs

Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting

Publisher: Food & Agriculture Org.

Published: 2006

Total Pages: 124

ISBN-13: 9789251055533

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Joint FAO/WHO Expert Committee on Food Additives, 66th meeting, Rome, 22-28 February 2006

Veterinary Drug Residues
Veterinary Drug Residues

Author: R. J. Heitzman

Publisher: Wiley-Blackwell

Published: 1994

Total Pages: 512

ISBN-13: 9780632037865

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The purpose of this second edition is to bring together the current rapid developments and activities in residues of veterinary drugs within the European Community. The EEC legislation is summarised. There is information on the Reference Laboratories, the Maximum Residues Limits (MRL) and the criteria for the methods to be used for routine analysis of residues by Member States and third countries wishing to export meat to the EC. The current state of examination of residues practised and the analytical methods used in Member States is described in detail. There is a section on quality assurance in the laboratory and also supporting information on residues and chemical/physical data of the most important veterinary drugs

Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin
Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin

Author: V.K. Agarwal

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 260

ISBN-13: 1461533562

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In the last three decades. use of antibiotics/drugs in animal husbandry programs has grown tremendously. Antibiotics/drugs are used therapeutically to cure diseases. and subtherapeutically to control the outbreak of diseases, improve feed efficiency and promote growth. The presence of antibiotic/drug residues in food products of animal origin. i.e •• meat, poultry and milk, can be a potential health hazard to consumers. Significant research is being done to develop new methods or to improve on existing methods to confirm and quantitatively determine the antibiotic/drug residues in meat, poultry and milk. This book covers recent development and application of various analytical techniques for the determination of antibiotic/drug residues in food products of animal origin. I thank the authors for their time and efforts in preparing the manuscripts and "all the reviewers for reviewing the manuscripts. I also thank to the Division of Agricultural and Food Chemistry of the American Chemical Society for sponsoring the symposium and Hewlett Packard, Palo Alto, CA, Perkin Elmer Corp., Norwalk, CT, Millipore Corporation, Milford, MA, and Kraft General Foods, Glenview, IL, for their generous financial support for the symposium. Vipin K. Agarwal New Haven, CT v CONTENTS Importance of Laboratory Validations and Accurate Descriptions of Analytical Procedures for Drug Residues in Foods ................. .

Residue Evaluation of Certain Veterinary Drugs
Residue Evaluation of Certain Veterinary Drugs

Author: Food and Agriculture Organization of the United Nations

Publisher: Food & Agriculture Org.

Published: 2018-05-29

Total Pages: 357

ISBN-13: 9251305366

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This volume of FAO JECFA Monographs contains residue evaluation of certain veterinary drugs prepared at the 85th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Geneva, 17–26 October 2017. This was the twenty-fifth JECFA meeting specifically convened to consider residues of veterinary drugs in food. The Committee elaborated principles for evaluating the safety of residues of veterinary drugs in food, for establishing acceptable daily intakes (ADIs) and acute reference doses (ARfDs) and for recommending maximum residue limits (MRLs) for such residues when the drugs under consideration are administered to food-producing animals in accordance with good practice in the use of veterinary drugs (GVP). Furthermore, the committee evaluated the safety of residues of eight veterinary drugs and responded to specific concerns raised by the Codex Committee on Residues of Veterinary Drugs in Foods. The enclosed monographs provide the scientific basis for the recommendations of MRLs, including information on chemical identity and properties of the compounds, pharmacokinetics and metabolism, residue depletion studies and analytical methods validated and used for the detection and quantification of the compounds. This publication and other documents produced by JECFA contain information that is useful to all those who work with or are involved with recommending or controlling maximum residue limits for veterinary drugs in food.

Residue Evaluation of Certain Veterinary Drugs
Residue Evaluation of Certain Veterinary Drugs

Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting

Publisher: Food & Agriculture Organization of the UN (FAO)

Published: 2014

Total Pages: 248

ISBN-13:

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This document contains monographs on residue evaluations of certain veterinary drugs, prepared at the seventy-eight meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which was held in Geneva, Switzerland, from 5 to 14 November 2013. Four substances were evaluated for the first time--emamectin benzoate, gentian violet, lasalocid sodium and zilpaterol hydrochloride. Four additional substances were re-evaluated--derquantel, ivermectin, monepantel and recombinant bovine somatotrophins. The monographs provide information on chemical identity and properties of the compounds, pharmacokinetics and metabolism, residue depletion studies and analytical methods validated and used for the detection and quantification of the compounds. In addition, this document provides an overview of the pilot project to evaluate alternative approaches to estimate daily intakes of residues of veterinary drugs in foods and provides guidance on the extrapolation of MRLs to minor species and for the establishment of MRLs in honey. This publication and other documents produced by JECFA contain information that is useful to all those who work with or are involved with recommending or controlling maximum residue limits for veterinary drugs in foods of animal origin.

Strategies for Reducing Drug and Chemical Residues in Food Animals
Strategies for Reducing Drug and Chemical Residues in Food Animals

Author: Ronald E. Baynes

Publisher: John Wiley & Sons

Published: 2014-09-15

Total Pages: 340

ISBN-13: 0470247525

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Highlighting international approaches; the book details strategies to minimize contamination, residue monitoring programs, and classes of drugs and chemicals that pose contaminant risk in livestock. Focuses attention on drug and chemical residues in edible animal products Covers novel computational, statistical, and mathematical strategies for dealing with chemical exposures in food animals Details major drug classes used in food animal production and their residue risks Highlights efforts at harmonizing and the differences among areas like US, EU, Canada, Australia, South America, China, and Asia, where the issue of chemical exposures has significant impact on livestock products Ties veterinary clinical practice and the use of these drugs in food animals with regulatory standards and mitigation practices

Residue evaluation of certain veterinary drugs – Joint FAO/WHO Expert Committee on Food Additives, Ninety-eighth Meeting 20–29 February 2024
Residue evaluation of certain veterinary drugs – Joint FAO/WHO Expert Committee on Food Additives, Ninety-eighth Meeting 20–29 February 2024

Author: World Health Organization

Publisher: World Health Organization

Published: 2024-10-23

Total Pages: 120

ISBN-13: 9240101411

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This volume of FAO JECFA Monographs contains residue evaluation of certain veterinary drugs prepared at the 98th meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held from 20 to 29 February 2024. This JECFA meeting was convened specifically to consider residues of veterinary drugs in food-producing animal species. The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and/or acute reference doses (ARfDs), and to recommend maximum residue limits (MRLs) for substances when they are administered to food-producing animals in accordance with good veterinary practice (GVP) in the use of veterinary drugs. The present volume contains monographs on the evaluations of residue data of substances scheduled for evaluation at the request of the Codex Committee on Residues of Veterinary Drugs in Food. A summary of the recommendations on compounds is also presented in this report. The enclosed monographs provided the scientific basis for the recommendations of MRLs.

Evaluation of Certain Veterinary Drug Residues in Food
Evaluation of Certain Veterinary Drug Residues in Food

Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting

Publisher: World Health Organization

Published: 2009

Total Pages: 144

ISBN-13: 9241209542

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including a hypothesis-driven decision tree approach for the safety evaluation of residues of veterinary drugs; comments on the Committee for Veterinary Products for Medicinal Use reflection paper on the new approach developed by JECFA for exposure and maximum residue limit (MRL) assessment of residues; residues of veterinary drugs in honey and possible approaches to derive MRLs for this commodity; comments on a paper entitled "Risk-assessment policies: Differences among jurisdictions"; and the use of no-observed-effect level (NOEL) and no-observed-adverse-effect level (NOAEL) in JECFA assessments. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (avilamycin, tilmicosin, tylosin), one authentic (triclabendazole), one production aid (melengestrol acetate), two antimicrobial agents and production aids (monesin and narasin), a glucocorticosteroid (dexamethasone) and an antimicrobial agent ands contaminant (malachite green). Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes (ADI's) and proposed MRL's.