Adipose Tissue in Health and Disease
Adipose Tissue in Health and Disease

Author: Todd Leff

Publisher: John Wiley & Sons

Published: 2010-03-19

Total Pages: 530

ISBN-13: 9783527629534

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This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Angiogenesis in Adipose Tissue
Angiogenesis in Adipose Tissue

Author: Yihai Cao

Publisher: Springer Science & Business Media

Published: 2013-09-05

Total Pages: 374

ISBN-13: 1461480698

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Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures. The vascular alteration plays an active role in regulation of adipose tissue size and functions. Targeting blood vessels in the adipose tissue have demonstrated to be a novel approach for possibly treatment of cancer, obesity and other metabolic diseases. This book provides the most updated information on this type research and discusses future opportunities for therapy..

Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

Author: Changjun Yin

Publisher: Frontiers Media SA

Published: 2017-05-22

Total Pages: 237

ISBN-13: 2889451801

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The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.

Inflammation and Atherosclerosis
Inflammation and Atherosclerosis

Author: Georg Wick

Publisher: Springer Science & Business Media

Published: 2011-12-03

Total Pages: 628

ISBN-13: 370910338X

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It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.

Adipose Tissue and Inflammation
Adipose Tissue and Inflammation

Author: Atif B. Awad

Publisher: CRC Press

Published: 2009-10-08

Total Pages: 247

ISBN-13: 1040171273

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The American Obesity Association identifies obesity's link to numerous medical conditions, including hypertension, type 2 diabetes, cardiovascular disease, several cancers, and a host of inflammatory disorders. Evidence indicates that inflammation has more than a corollary relation with obesity; that in fact, obesity itself manifests a low-grade, m

Food Factors for Health Promotion
Food Factors for Health Promotion

Author: Toshikazu Yoshikawa

Publisher: Karger Medical and Scientific Publishers

Published: 2009-01-01

Total Pages: 236

ISBN-13: 3805590970

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Food factors are considered to be critical for human health promotion and play an important role in the prevention of life-style related diseases. One of the major challenges in this context is to determine the multiple factors associated with the causes of these diseases, as well as to develop a method of detecting changes in the initial stage and to establish a diagnostic approach that can be used in prevention studies of food factors.This publication features chapters on genomics, proteomics, bioavailability and safety, antioxidants, life-style related diseases and on chemoprevention and cancer. Basic scientists with a focus on food factors, clinicians planning a prospective preventive study of food factors in life-style-related diseases, as well as company researchers studying health promotional effects of food or food ingredients will find a wealth of information in this book.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Author: Debasis Bagchi

Publisher: Academic Press

Published: 2012-01-31

Total Pages: 553

ISBN-13: 0123850835

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Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options

Epicardial Adipose Tissue
Epicardial Adipose Tissue

Author: Gianluca Iacobellis

Publisher: Springer Nature

Published: 2020-03-25

Total Pages: 198

ISBN-13: 3030405702

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This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease. It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease. Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.

Emerging Societies
Emerging Societies

Author: Satish C. Kalhan

Publisher: Karger Medical and Scientific Publishers

Published: 2009-01-01

Total Pages: 281

ISBN-13: 3805590091

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In many developing and emerging societies, the coexistence of malnutrition and obesity is becoming increasingly prevalent. Caused by a rapid change in terms of economic growth and increased availability of food, the main challenge of this nutrition transition is the balance between short-term benefits and long-term risks of increased metabolic diseases.The publication at hand starts with an epidemiological overview, including regional case studies from India, China and Africa. This is followed by an in-depth evaluation of the phenomenon, focussing on the origin and prevalence of malnutrition and its link to obesity, the possible mechanisms of metabolic injury, and the strategies for preventing the projected epidemic of non-communicable disease. Also stressed is the need for further research to determine which population segments should be targeted at what stages of their lifecycle in order to achieve optimal results.Written by an international panel of experts, this volume will be of particular value for pediatricians, perinatologists, obstetricians, endocrinologists, public health scientists and epidemiologists.