RACK CANCER

RACK CANCER

Author: Lori Whitney Phair

Publisher: Xlibris Corporation

Published: 2012-08-21

Total Pages: 112

ISBN-13: 1479701300

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Dedicated to every brave warrior who has ever fought cancer. Th ose who survived, those who are still fighting, and those who lost the battle. There we sat at the poolside café in the gated community in Florida, where my parents have lived for the past twenty-some-odd years. I had received the heart-wrenching diagnosis less than a week earlier and had just recently broken the news to my two young children. So there we sat, just the four of us, at a table, eating our lunch, just as we had done so many times before during our annual December holiday visit. I had ordered a salad; my twelve-year-old son, Nick, was munching on a hot dog; and my husband, Jim, was eating a cheeseburger. My petite nine-year-old daughter, Whitney, was chomping away on a rack of BBQ ribs. (Th is is the same child who decided on the codfi sh when we took her to the International House of Pancakes. Th e second time we took her there, she went with the pot roast.) Nick had a million questions about the cancer. “How do they know it didn’t spread?” “How did you get it?” “Is it contagious?” and so on. Whitney just sat there, her big eyes welling up with tears from time to time, looking at me longingly, as if she wanted to jump in my pocket and stay in it forever. So we all sat there, trying to eat, Jim and I attempting to answer the questions as best we could to ease their worries. During the course of the meal, Jim, who always gets such a charge out of Whitney’s dietary intake, made many references to the “rack” that she was consuming. “How’s the rack?” “Is the rack good?” “Th e rack looks delicious!” “Can I try some of the rack?” Finally, I could take it no longer. I turned to my saint of a husband and said, “Under the circumstances, sweetie, do you think you could STOP saying the word rack so much?” My husband, who is ALWAYS my best audience, started laughing. Nick, who is ALWAYS asking questions, wanted to know why that was funny. Jim went on to explain to him that the word rack is sometimes used as a slang term for a set of woman’s breasts. Whitney, with bone in hand and a face full of BBQ sauce, turned to us and said, “Oh, so Mommy has rack cancer?” There you have it. From that day forward, in my little corner of the world, my medical condition became known as rack cancer. It was much less frightening that way.


How Connie Got Her Rack Back

How Connie Got Her Rack Back

Author: Constance Bramer

Publisher: FriesenPress

Published: 2012-02

Total Pages: 286

ISBN-13: 1770972900

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Let's face it, when a white coat touting doctor and her posse deliver a breast cancer diagnosis, your life has a way of turning upside down and even a little sideways. And when you're a 39 year old single, working mother of two, the roller coaster ride that ensues will either lead you to a straight jacket or a back brace. Connie Bramer gives laugh out loud humor to her adventure, along with poignant moments of self-discovery as she blogs her way to good health. Follow along with her adventure and bare witness to her crazy antics, the comments of love she received, and the unwaivering support of her friends and family that helped to get her through...


Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer

Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer

Author: Michail Ignatiadis

Publisher: Springer Science & Business Media

Published: 2012-04-23

Total Pages: 245

ISBN-13: 3642281605

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This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.


Rack Cancer

Rack Cancer

Author: Lori Whitney Phair

Publisher: Xlibris Corporation

Published: 2012-08

Total Pages: 112

ISBN-13: 1479701289

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Dedicated to every brave warrior who has ever fought cancer. Th ose who survived, those who are still fighting, and those who lost the battle. There we sat at the poolside café in the gated community in Florida, where my parents have lived for the past twenty-some-odd years. I had received the heart-wrenching diagnosis less than a week earlier and had just recently broken the news to my two young children. So there we sat, just the four of us, at a table, eating our lunch, just as we had done so many times before during our annual December holiday visit. I had ordered a salad; my twelve-year-old son, Nick, was munching on a hot dog; and my husband, Jim, was eating a cheeseburger. My petite nine-year-old daughter, Whitney, was chomping away on a rack of BBQ ribs. (Th is is the same child who decided on the codfi sh when we took her to the International House of Pancakes. Th e second time we took her there, she went with the pot roast.) Nick had a million questions about the cancer. "How do they know it didn't spread?" "How did you get it?" "Is it contagious?" and so on. Whitney just sat there, her big eyes welling up with tears from time to time, looking at me longingly, as if she wanted to jump in my pocket and stay in it forever. So we all sat there, trying to eat, Jim and I attempting to answer the questions as best we could to ease their worries. During the course of the meal, Jim, who always gets such a charge out of Whitney's dietary intake, made many references to the "rack" that she was consuming. "How's the rack?" "Is the rack good?" "Th e rack looks delicious!" "Can I try some of the rack?" Finally, I could take it no longer. I turned to my saint of a husband and said, "Under the circumstances, sweetie, do you think you could STOP saying the word rack so much?" My husband, who is ALWAYS my best audience, started laughing. Nick, who is ALWAYS asking questions, wanted to know why that was funny. Jim went on to explain to him that the word rack is sometimes used as a slang term for a set of woman's breasts. Whitney, with bone in hand and a face full of BBQ sauce, turned to us and said, "Oh, so Mommy has rack cancer?" There you have it. From that day forward, in my little corner of the world, my medical condition became known as rack cancer. It was much less frightening that way.


Circulating Tumor Cells

Circulating Tumor Cells

Author: Richard J. Cote

Publisher: Springer Nature

Published: 2023-08-01

Total Pages: 672

ISBN-13: 3031229037

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It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes). CTC play a central role in tumor dissemination and metastasis, and have been established as an important evaluative and research tool in advanced cancer, and potentially important in early stage disease. CTC defines tumor cells circulating in blood, while Disseminated Tumor Cells (DTC) refers to tumor cells identified in bone marrow. CTC/DTC are extremely rare events, even in late stage cancer, and their detection has presented enormous technical challenges, with the emergence of multiple technologies developed to address these challenges, including enrichment, identification and sophisticated analytical techniques to evaluate CTC and other cells in circulation that may also be important in the biology of metastasis. As foundational as CTC/DTC has been, the field of liquid biopsy has expanded well beyond these analytes. The relevance of circulating nucleic acids derived from tumor cells has quickly progressed from research to the clinic. There are now well established clinical applications for using ctDNA/RNA to determine therapeutic targets, follow disease progression and detect cancer recurrence long before routine clinical methods. One of the most exciting new areas of work is the possibility of using these circulating tumor derived nucleic acids to detect cancer at its earliest and potentially most curable stages. Another new and burgeoning area is the detection and analysis of ctExosomes. These highly abundant particles which are actively secreted from tumor (and indeed all) cells represent a novel way to detect and define multiple analytes of importance, including proteins, DNA and meDNA, RNA, miRNA, and other cell components that are protected and preserved in these compact structures. This second edition of Circulating Tumor Cells: Advances in Liquid Biopsy Technologies is entirely new and brings together leaders and innovators in the field of liquid biopsy, including basic and molecular biologists, chemists, engineers, statisticians, experts in tumor banking, test developers, research administrators and clinicians. A special feature of this book is that it includes chapters from the members of the US National Cancer Institute Liquid Biopsy Consortium. This edition also includes many of the participants of the latest international meeting on the Advances in Circulating Tumor Cells (ACTC) which is held in Greece every two years and gathers the most important liquid biopsy investigators from around the world. Thus, this edition represents the most comprehensive and up-to-date resource for those who want to further explore the exciting field of CTC and other liquid biopsy technologies. The new edition will be useful to a wide audience including scientists studying metastasis, cancer researchers, translational scientists, oncologic surgeons, medical oncologists, members of the biopharmaceutical industry, and graduate and undergraduate students studying cancer biology.


How Connie Got Her Rack Back

How Connie Got Her Rack Back

Author: Constance Bramer

Publisher: FriesenPress

Published: 2012-02

Total Pages: 286

ISBN-13: 1770972919

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Let's face it, when a white coat touting doctor and her posse deliver a breast cancer diagnosis, your life has a way of turning upside down and even a little sideways. And when you're a 39 year old single, working mother of two, the roller coaster ride that ensues will either lead you to a straight jacket or a back brace. Connie Bramer gives laugh out loud humor to her adventure, along with poignant moments of self-discovery as she blogs her way to good health. Follow along with her adventure and bare witness to her crazy antics, the comments of love she received, and the unwaivering support of her friends and family that helped to get her through...


Lung Cancer

Lung Cancer

Author: Barbara Driscoll

Publisher: Springer Science & Business Media

Published: 2008-01-18

Total Pages: 589

ISBN-13: 1592593232

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The Methods in Molecular Medicine series is intended as a resource for both novice and experienced investigators attempting to diversify their tech- logical base in research. Lung Cancer: Volume 1: Molecular Pathology Me- ods and Reviews presents an overview of the current status of assays employed to detect and characterize the multitude of pathologies that contribute to the development of this deadly disease. As with all volumes in the Methods in Molecular Medicine series, the reader should find that each methods-based chapter provides clear instructions for the performance of various protocols, supplemented by additional technical notes that provide valuable insight. These notes are designed to enable the reader to acquire the techniques described with a proficiency not easily achieved by re- ing standard method formats. No volume can exhaustively cover every aspect of biological research and there will be gaps in this endeavor that one or another research group will id- tify. Each section herein could readily be expanded into a book in its own right. However, I have sought to include a spectrum of techniques that should allow for the acquisition of key skills in each area covered.


The Anti-Cancer Cookbook

The Anti-Cancer Cookbook

Author: Julia B. Greer

Publisher: Sunrise River Press

Published: 2008-11-07

Total Pages: 227

ISBN-13: 1934716294

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Scrumptious recipes chock-full of powerful antioxidants that may significantly slash your risk of a broad range of cancer types.


Current Cancer Biomarkers

Current Cancer Biomarkers

Author: Farhadul Islam

Publisher: Bentham Science Publishers

Published: 2023-01-30

Total Pages: 401

ISBN-13: 9815079379

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Current Cancer Biomarkers is a comprehensive review on the status of biological markers for various types of cancer. It aims to update readers on current developments on the subject. The contents are divided into 5 sections covering a wide range of biomarkers and their diagnostic applications. The range of tumour biomarkers referenced here gives insights into molecular mechanisms behind cancer, including initiation, development, progression, prognosis, response to the therapeutic modalities, recurrence, and point-of-care application to detect cancer. Key features - Introduction of the basic features of cancer markers - Comprehensive and updated coverage of potential and effective biomarkers including genomic, epigenomic, transcriptomic, proteomic, cellular and morphologic factors - Information on biomarkers in many types of cancers including breast cancer, colorectal cancer, skin cancer, leukemia, liver cancer and prostate cancer - Applications of biomarkers in cancer diagnosis - Structured contents with easy-to-understand sections and headings - References for advanced readers The updated information about different aspects of cancer markers in the experimental and clinical setting will enrich the reader's understanding of the disease. The information serves as a resource to help in better management of cancer patients and understanding cancer biology when planning medical research projects. The book is intended as a reference for a diverse audience: biomedical science students, medical students, academics, researchers, clinicians and multidisciplinary teams involved in cancer management and research.