Quantitative Trait Loci Analysis in Animals

Quantitative Trait Loci Analysis in Animals

Author: Joel Ira Weller

Publisher: CABI

Published: 2009

Total Pages: 288

ISBN-13: 1845937341

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Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This book covers various statistical methods that have been used or proposed for detection and analysis of QTL and marker-and gene-assisted selection in animal genetics and breeding.


Genetics and Analysis of Quantitative Traits

Genetics and Analysis of Quantitative Traits

Author: Michael Lynch

Publisher: Sinauer Associates Incorporated

Published: 1998-01

Total Pages: 980

ISBN-13: 9780878934812

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Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.


Statistical Genetics of Quantitative Traits

Statistical Genetics of Quantitative Traits

Author: Rongling Wu

Publisher: Springer Science & Business Media

Published: 2007-07-17

Total Pages: 371

ISBN-13: 038768154X

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This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.


Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Author: Robert T. Gerlai

Publisher: Academic Press

Published: 2018-04-24

Total Pages: 710

ISBN-13: 0128041161

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Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts


Genetic Dissection of Complex Traits

Genetic Dissection of Complex Traits

Author: D.C. Rao

Publisher: Academic Press

Published: 2008-04-23

Total Pages: 788

ISBN-13: 0080569110

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The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more


DNA Fingerprinting: State of the Science

DNA Fingerprinting: State of the Science

Author: Sergio D. Pena

Publisher: Springer Science & Business Media

Published: 1993-07-01

Total Pages: 484

ISBN-13: 9783764329068

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DNA fingerprinting had a well-defined birthday. In the March 7, 1985 issue of Nature, Alec Jeffreys and coworkers described the first develop ment ofmu1tilocus probes capable of simultaneously revealing hypervari ability at many loci in the human genome and called the procedure DNA fingerprinting. It was a royal birth in the best British tradition. In a few months the emerging technique had permitted the denouement of hith erto insoluble immigration and paternity disputes and was already heralded as a major revolution in forensic sciences. In the next year (October, 1986) DNA fingerprinting made a dramatic entree in criminal investigations with the Enderby murder case, whose story eventually was turned into a best-selling book ("The Blooding" by Joseph Wambaugh). Today DNA typing systems are routinely used in public and commercial forensic laboratories in at least 25 different countries and have replaced conventional protein markers as the methods of choice for solving paternity disputes and criminal cases. Moreover, DNA fingerprinting has emerged as a new domain of intense scientific activity, with myriad applications in just about every imaginable territory of life sciences. The Second International Conference on DNA Fingerprinting, which was held in Belo Horizonte, Brazil in November of 1992, was a clear proof of this.


Gene-Mapping Techniques and Applications

Gene-Mapping Techniques and Applications

Author: Lawrence B. Schook

Publisher: CRC Press

Published: 2020-07-24

Total Pages: 353

ISBN-13: 100010463X

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This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.


Statistical Genomics

Statistical Genomics

Author: Ben Hui Liu

Publisher: CRC Press

Published: 2017-11-22

Total Pages: 642

ISBN-13: 1351414534

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Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.


Quantitative Genetics in the Wild

Quantitative Genetics in the Wild

Author: Anne Charmantier

Publisher: Oxford University Press

Published: 2014

Total Pages: 293

ISBN-13: 019967423X

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This book gathers the expertise of 30 evolutionary biologists from around the globe to highlight how applying the field of quantitative genetics - the analysis of the genetic basis of complex traits - aids in the study of wild populations.