The Mathematical Heritage of C F Gauss
The Mathematical Heritage of C F Gauss

Author: George M. Rassias

Publisher: World Scientific

Published: 1991-09-01

Total Pages: 930

ISBN-13: 9789810237974

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This volume is a collection of original and expository papers in the fields of Mathematics in which Gauss had made many fundamental discoveries. The contributors are all outstanding in their fields and the volume will be of great interest to all research mathematicians, research workers in the history of science, and graduate students in Mathematics and Mathematical Physics.

Reversible Ligand Binding
Reversible Ligand Binding

Author: Andrea Bellelli

Publisher: John Wiley & Sons

Published: 2018-01-09

Total Pages: 309

ISBN-13: 111923848X

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Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions—providing a comprehensive view of the various biochemical considerations that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of the experiment, which aids in showing clear evidence of biochemical features that may otherwise escape notice. Classical experiments are reviewed in order to further highlight the importance of the design of the experiment. Overall, the book supplies students with the understanding that is necessary for interpreting ligand binding experiments, formulating plausible reaction schemes, and analyzing the data according to the chosen model(s). Topics covered include: theory of ligand binding to monomeric proteins; practical considerations and commonly encountered problems; oligomeric proteins with multiple binding sites; ligand binding kinetics; hemoglobin and its ligands; single-substrate enzymes and their inhibitors; two-substrate enzymes and their inhibitors; and rapid kinetic methods for studying enzyme reactions. Bridges theory of ligand binding and allostery with experiments Applies historical and physical insight to provide a clear understanding of ligand binding Written by a renowned author with long-standing research and teaching expertise in the area of ligand binding and allostery Based on FEBS Advanced Course lectures on the topic Reversible Ligand Binding: Theory and Experiment is an ideal text reference for students and scientists involved in biophysical chemistry, physical biochemistry, biophysics, molecular biology, protein engineering, drug design, pharmacology, physiology, biotechnology, and bioengineering.

Individuality and Entanglement
Individuality and Entanglement

Author: Herbert Gintis

Publisher: Princeton University Press

Published: 2016-11-08

Total Pages: 379

ISBN-13: 0691172919

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A richly transdisciplinary account of some fundamental characteristics of human societies and behavior In this book, acclaimed economist Herbert Gintis ranges widely across many fields—including economics, psychology, anthropology, sociology, moral philosophy, and biology—to provide a rigorous transdisciplinary explanation of some fundamental characteristics of human societies and social behavior. Because such behavior can be understood only through transdisciplinary research, Gintis argues, Individuality and Entanglement advances the effort to unify the behavioral sciences by developing a shared analytical framework—one that bridges research on gene-culture coevolution, the rational-actor model, game theory, and complexity theory. At the same time, the book persuasively demonstrates the rich possibilities of such transdisciplinary work. Everything distinctive about human social life, Gintis argues, flows from the fact that we construct and then play social games. Indeed, society itself is a game with rules, and politics is the arena in which we affirm and change these rules. Individuality is central to our species because the rules do not change through inexorable macrosocial forces. Rather, individuals band together to change the rules. Our minds are also socially entangled, producing behavior that is socially rational, although it violates the standard rules of individually rational choice. Finally, a moral sense is essential for playing games with socially constructed rules. People generally play by the rules, are ashamed when they break the rules, and are offended when others break the rules, even in societies that lack laws, government, and jails. Throughout the book, Gintis shows that it is only by bringing together the behavioral sciences that such basic aspects of human behavior can be understood.

Expectation, Enterprise and Profit
Expectation, Enterprise and Profit

Author: G. L. S. Shackle

Publisher: Transaction Publishers

Published: 2007-05-01

Total Pages: 162

ISBN-13: 9780202365985

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Production is a complex system of interdependent activities, necessary to the system as a whole, which itself depends on the continuance of each individual activity that composes it. In such a system, resources must be committed to specific technological purposes long in advance to the ultimate sale of goods to the consumer. The success of such an enterprise system rests on the durability of the instruments it uses. These are so complex, sensitive, and powerful that their huge expense can be recovered only if they can be used for many years. Yet when the decision is made to invest in them, those years of use are in the future and the conditioning circumstances are unobservable and unknown. The firm in Western economies is the essential institutional means of confronting this problem of uncertainty, Expectation, Enterprise and Profit: The Theory of the Firm is concerned with the nature and mode of life of the firm as a means of policy formation in the face of uncertainty. This book offers a concise treatment and excellent analysis of the major concepts studied in a first course in the theory of the firm. G. L. S. Shackle (1903-1992) was Brunner Professor of Economic Science at the University of Liverpool and was widely known for a succession of major contributions to economic studies, including Expectation in Economics, Economics for Pleasure, A Scheme of Economic Theory, and The Years of High Theory.