Principles and Practice of Stereotactic Radiosurgery
Principles and Practice of Stereotactic Radiosurgery

Author: Lawrence S. Chin

Publisher: Springer

Published: 2015-01-05

Total Pages: 825

ISBN-13: 1461483638

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Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference. Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.

Chess Results, 1951-1955
Chess Results, 1951-1955

Author: Gino Di Felice

Publisher: McFarland

Published: 2010-03-10

Total Pages: 607

ISBN-13: 078645556X

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This comprehensive chronological reference work lists the results of men's chess competitions all over the world--individual and team matches, from 1951 through 1955--with sources. Entries record location and, when available, the group that sponsored the event. First and last names of players are included whenever possible and are standardized for easy reference. Compiled from contemporary sources such as newspapers, periodicals, tournament records and match books, this work contains 1,620 tournament crosstables and 144 match scores. It is indexed by events and by players.

Inhibiting PARP as a Strategic Target in Cancer
Inhibiting PARP as a Strategic Target in Cancer

Author: Christina Annunziata

Publisher: Frontiers Media SA

Published: 2016-08-05

Total Pages: 99

ISBN-13: 288919955X

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Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have specific defects in DNA repair pathways, and that these defects may predispose for sensitivity and resistance to various classes of cytotoxic agents. Breast, ovarian and other cancers develop in the setting of inherited DNA repair deficiency, and these cancers may be more sensitive to cytotoxic agents that induce DNA strand breaks, as well as to inhibitors of PARP activity. A series of recent clinical trials has tested whether PARP inhibitors can achieve synthetic lethality in hereditary DNA repair-deficient tumors. At the current time, mutation of BRCA serves as a potential, but not comprehensive, biomarker to predict response to PARP inhibitor therapy. Mechanisms of resistance to PARP inhibitors are only recently being uncovered. Future studies seek to identify sporadic cancers that harbor genomic instability rendering susceptibility to PARP inhibitors that compound lethal DNA damage.

Handbook of Evidence-Based Radiation Oncology
Handbook of Evidence-Based Radiation Oncology

Author: Eric K. Hansen

Publisher: Springer

Published: 2018-05-07

Total Pages: 946

ISBN-13: 3319626426

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The Third Edition of Handbook of Evidence-Based Radiation Oncology updates and revises the previous successful editions and serves as a key reference for radiation oncology professionals. Organized by body site, concise clinical chapters provide easy access to critical information. Important "pearls" of epidemiology, anatomy, pathology, and clinical presentation are highlighted. The key elements of the work-up are listed, followed by staging and/or risk classification systems. Treatment recommendations are discussed based on stage, histology, and/or risk classification. Brief summaries of key trials and studies provide the rationale for the recommendations. Practical guidelines for radiation techniques are described and complications and follow-up guidelines are outlined. The Third Edition incorporates new key studies and trials to reflect current radiation oncology practice; includes the most recent staging systems; and features new color illustrations and anatomic atlases to aid in treatment planning. This book is a valuable resource for students, resident physicians, fellows, and other practitioners of radiation oncology.

Back to School for Parents
Back to School for Parents

Author: Michael D. Buford BA MEd

Publisher: Xlibris Corporation

Published: 2010-02-03

Total Pages: 83

ISBN-13: 1450020399

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What can I do as a parent to help my child receive the best education in the public school? What proven strategies are available for an ordinary parent to use to help his/her child have greater success in the classroom? Does my child have a better chance in receiving a quality education if I am involved in his day to day education? The answers to these three questions are crucial for parents today if their child is to have success in the classroom and receive a quality education! BACK TO SCHOOL FOR PARENTS addresses each of these questions providing the parent who has limited or advanced education a useful tool to help the school-aged child have greater success in the public school.