Process Development in Antibiotic Fermentations

Process Development in Antibiotic Fermentations

Author: C. T. Calam

Publisher: Cambridge University Press

Published: 1987-07-31

Total Pages: 232

ISBN-13: 9780521304900

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Process development in antibiotic fermentation is of microbiological and commercial importance and this book gives a consistent treatment of the area.


Microbial Process Development

Microbial Process Development

Author: H. W. Doelle

Publisher: World Scientific

Published: 1994

Total Pages: 332

ISBN-13: 9789810215156

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This book outlines the vast potential of the microbial catalyst for present and future microbial process development without waste formation, leading to a clean environment. It is intended to inspire scientists and biochemical engineers to isolate new microorganisms from nature and to explore the optimal potential of the genotype before altering its code through genetical engineering. This book is structured to encourage the reader to use basic scientific and biochemical engineering concepts for the development of new and improved fermentation technology industries. It leads the reader from aspects of isolation, identification and preservation of microbial strains to the use of thermodynamics and their biochemistry to the final endproducts and their purification. Special emphasis is given to the restoration of our present and the preservation of our future environment using socioecological and biotechnological concepts. Drawing on many years of experience teaching and working in the Asia-Pacific and Africa, the author presents an interesting, informative and enlightening account of his knowledge in this field.


Basic Biotechnology

Basic Biotechnology

Author: Colin Ratledge

Publisher: Cambridge University Press

Published: 2006-05-25

Total Pages: 653

ISBN-13: 0521840317

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Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. A distinctive feature of this text are the discussions of the public perception of biotechnology and the business of biotechnology, which set the science in a broader context. This comprehensive textbook is essential reading for all students of biotechnology and applied microbiology, and for researchers in biotechnology industries.


Applications of Biotechnology in Traditional Fermented Foods

Applications of Biotechnology in Traditional Fermented Foods

Author: National Research Council

Publisher: National Academies Press

Published: 1992-02-01

Total Pages: 208

ISBN-13: 0309046858

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In developing countries, traditional fermentation serves many purposes. It can improve the taste of an otherwise bland food, enhance the digestibility of a food that is difficult to assimilate, preserve food from degradation by noxious organisms, and increase nutritional value through the synthesis of essential amino acids and vitamins. Although "fermented food" has a vaguely distasteful ring, bread, wine, cheese, and yogurt are all familiar fermented foods. Less familiar are gari, ogi, idli, ugba, and other relatively unstudied but important foods in some African and Asian countries. This book reports on current research to improve the safety and nutrition of these foods through an elucidation of the microorganisms and mechanisms involved in their production. Also included are recommendations for needed research.


Fermentation Processes: Emerging and Conventional Technologies

Fermentation Processes: Emerging and Conventional Technologies

Author: Mohamed Koubaa

Publisher: John Wiley & Sons

Published: 2021-02-11

Total Pages: 240

ISBN-13: 1119505844

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Explores the use of conventional and novel technologies to enhance fermentation processes Fermentation Processes reviews the application of both conventional and emerging technologies for enhancing fermentation conditions, examining the principles and mechanisms of fermentation processes, the microorganisms used in bioprocesses, their implementation in industrial fermentation, and more. Designed for scientists and industry professionals alike, this authoritative and up-to-date volume describes how non-conventional technologies can be used to increase accessibly and bioavailability of substrates by microorganisms during fermentation, which in turn promotes microbial growth and can improve processes and productivity across the agri-food, nutraceutical, pharmaceutical, and beverage industries. The text begins by covering the conventional fermentation process, discussing cell division and growth kinetics, current technologies and developments in industrial fermentation processes, the parameters and modes of fermentation, various culture media, and the impact of culture conditions on fermentation processes. Subsequent chapters provide in-depth examination of the use of emerging technologies—such as pulsed electric fields, ultrasound, high-hydrostatic pressure, and microwave irradiation—for biomass fractionation and microbial stimulation. This authoritative resource: Explores emerging technologies that shorten fermentation time, accelerate substrate consumption, and increase microbial biomass Describes enhancing fermentation at conventional conditions by changing oxygenation, agitation, temperature, and other medium conditions Highlights the advantages of new technologies, such as reduced energy consumption and increased efficiency Discusses the integration and implementation of conventional and emerging technologies to meet consumer and industry demand Offers perspectives on the future direction of fermentation technologies and applications Fermentation Processes: Emerging and Conventional Technologies is ideal for microbiologists and bioprocess technologists in need of an up-to-date overview of the subject, and for instructors and students in courses such as bioprocess technology, microbiology, new product development, fermentation, food processing, biotechnology, and bioprocess engineering.


High Value Fermentation Products, Volume 1

High Value Fermentation Products, Volume 1

Author: Saurabh Saran

Publisher: John Wiley & Sons

Published: 2019-03-12

Total Pages: 548

ISBN-13: 1119460069

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Green technologies are no longer the “future” of science, but the present. With more and more mature industries, such as the process industries, making large strides seemingly every single day, and more consumers demanding products created from green technologies, it is essential for any business in any industry to be familiar with the latest processes and technologies. It is all part of a global effort to “go greener,” and this is nowhere more apparent than in fermentation technology. This book describes relevant aspects of industrial-scale fermentation, an expanding area of activity, which already generates commercial values of over one third of a trillion US dollars annually, and which will most likely radically change the way we produce chemicals in the long-term future. From biofuels and bulk amino acids to monoclonal antibodies and stem cells, they all rely on mass suspension cultivation of cells in stirred bioreactors, which is the most widely used and versatile way to produce. Today, a wide array of cells can be cultivated in this way, and for most of them genetic engineering tools are also available. Examples of products, operating procedures, engineering and design aspects, economic drivers and cost, and regulatory issues are addressed. In addition, there will be a discussion of how we got to where we are today, and of the real world in industrial fermentation. This chapter is exclusively dedicated to large-scale production used in industrial settings.


Annual Reports on Fermentation Processes

Annual Reports on Fermentation Processes

Author: D. Perlman

Publisher: Elsevier

Published: 2014-12-01

Total Pages: 399

ISBN-13: 148321379X

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Annual Reports on Fermentation Processes, Volume 1 furnishes a critical account of significant developments concerning fermentation processes. This book discusses the mutation, selection, and optimization of mutagenesis; fermentation substrates; and published accounts of computer-coupled fermentation systems. The waste materials as SCP substrates, immobilized cell processes, and microbial transformations of organic compounds are also elaborated. This publication likewise covers the microbiological and enzymatic conversion of ß-lactam antibiotics, microbiological production of chemical feedstocks, and aeration systems and their performance. Other topics include the toxicology and regulation of enzyme use, general considerations of immobilized enzyme systems, mutational biosynthesis, and biotransformations and the role of precursors. This volume is a good reference for students and researchers interested in fermentation research and developments.


Fermentation and Biochemical Engineering Handbook

Fermentation and Biochemical Engineering Handbook

Author: Henry C. Vogel

Publisher: William Andrew

Published: 1996-12-31

Total Pages: 831

ISBN-13: 0815517130

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This is a well-rounded handbook of fermentation and biochemical engineering presenting techniques for the commercial production of chemicals and pharmaceuticals via fermentation. Emphasis is given to unit operations fermentation, separation, purification, and recovery. Principles, process design, and equipment are detailed. Environment aspects are covered. The practical aspects of development, design, and operation are stressed. Theory is included to provide the necessary insight for a particular operation. Problems addressed are the collection of pilot data, choice of scale-up parameters, selection of the right piece of equipment, pinpointing of likely trouble spots, and methods of troubleshooting. The text, written from a practical and operating viewpoint, will assist development, design, engineering and production personnel in the fermentation industry. Contributors were selected based on their industrial background and orientation. The book is illustrated with numerous figures, photographs and schematic diagrams.


Current Developments in Solid-state Fermentation

Current Developments in Solid-state Fermentation

Author: Ashok Pandey

Publisher: Springer Science & Business Media

Published: 2008-09-16

Total Pages: 521

ISBN-13: 0387752137

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Over the period of last two decades, there has been significant resurgence in solid-state fermentation due to the numerous benefits it offers, especially in the engineering and environmental aspects. SSF has shown much promise in the development of several bioprocesses and products. This resurgence gained further momentum during the last 5-6 years with the developments in fundamental and applied aspects. A good deal of information has been generated in published literature and patented information. Several commercial ventures have come up based on SSF in different parts of the world. The contents are organized into four parts: Part 1 deals with the General and Fundamentals aspects of SSF; Part 2 deals with the production of bulk chemicals and products such as enzymes, organic acids, spores and mushrooms in SSF; Part 3 is on the use of SSF for specialty chemicals such as gibberellic acid, antibiotics and other pharmaceutically valuable secondary metabolites, pigments, and aroma compounds; Part 4 deals with the use of SSF miscellaneous application such as SSF for food and feed applications, agro-industrial residues as substrates in SSF and the production of silage and vermicompost.