Antiviral Chemotherapy 4

Antiviral Chemotherapy 4

Author: John Mills

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 432

ISBN-13: 1475792093

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The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the late stages of clinical trials. d4T is now licensed for HIV infection, famciclovir and the oral pro-drug of acyclovir, valacyclovir, are now licensed for VZV infections in some countries. Moreover. oral ganciclovir, cidofovir, and sorivudine are not far behind. Clinical trials with the second-site reverse transcriptase inhibitors and the protease inhibitors for HlV infection are proceeding rapidly and on a broad scale, and the preliminary results would suggest that several of these classes of drugs will be licensed as well. Despite this optimism, however, there is increasing evidence that antiviral-resistant strains of pathogenic viruses will be a significant problem, perhaps especially with therapy of HIV infection, and there remains a desperate need for improved drugs (with either improved efficacy or decreased toxicity, or both) for CMV and HIV infections. This book is the edited proceedings of the Fourth Triennial Conference on Antiviral Chemotherapy, held in San Francisco, in November 1994. The conference was sponsored by the University of California, San Francisco, and co-sponsored by the International Society for Antiviral Research (ISAR), the Macfarlane Burnet Centre for Medical Research in Melbourne, Australia, and the Australian National Centre for HIV Virology Research. The conference had been organized to present an overview of the field of antiviral chemotherapy.


Pocket Guide to GastrointestinaI Drugs

Pocket Guide to GastrointestinaI Drugs

Author: M. Michael Wolfe

Publisher: John Wiley & Sons

Published: 2014-01-02

Total Pages: 222

ISBN-13: 1118481550

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Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: Introduction of drug class Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations Dosing information for each GI condition and on- and off-label use Consistent use of both generic and trade names throughout Specific reference to drug use in pediatric patients and during pregnancy Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists.


Practical Guidelines in Antiviral Therapy

Practical Guidelines in Antiviral Therapy

Author: G.J. Galasso

Publisher: Elsevier

Published: 2002-01-21

Total Pages: 353

ISBN-13: 0080539378

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This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.


Hepatitis C

Hepatitis C

Author: Fred Askari

Publisher: Da Capo Press

Published: 2007-10-09

Total Pages: 202

ISBN-13: 0738211974

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Four million Americans have been stricken by Hepatitis C, and the numbers continue to grow. Covering every aspect of this serious liver disease, Dr. Fred Askari provides a clear and compassionate description of the complex medical issues that many doctors fail to adequately explain to their patients. Complete with a targeted resource list of support groups and organizations, Hepatitis C: The Silent Epidemic delivers the facts on the symptoms as well as up-to-the-minute news on drug and transplant treatment options.


Clinical Dilemmas in Viral Liver Disease

Clinical Dilemmas in Viral Liver Disease

Author: Graham Foster

Publisher: John Wiley & Sons

Published: 2011-09-22

Total Pages: 272

ISBN-13: 1444319604

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Clinical Dilemmas in Viral Liver Disease is a practicalup-to-date handbook providing answers to the questions andchallenges that arise in day-to-day practice. Each short chapter addresses a different topic and providesevidence-based guidance on subjects ranging from optimizing currentmanagement through to special management problems and noveltreatments. This book is suitable for all medical professionals involved inthe care of patients with viral liver disease: established andtrainee hepatologists, pediatric hepatologists, pathologists,radiologists, transplant surgeons and nurse specialists


HCV: The Journey from Discovery to a Cure

HCV: The Journey from Discovery to a Cure

Author: Michael J. Sofia

Publisher: Springer Nature

Published: 2019-11-23

Total Pages: 457

ISBN-13: 3030282074

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Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study the virus spurred the search for novel direct acting antiviral drugs to cure this disease. This global effort culminated in the development of direct acting antiviral drugs that led to cure rates approaching 100% in all patient populations after only 8-12 weeks of therapy. These efforts resulted in one of the greatest achievements in public health and provides the potential for eliminating HCV as a major disease worldwide. This volume is aimed at a broad audience of academic and industrial scientists interested in the discovery and development of drugs to treat viral diseases and those interested in reading about one of the most unique accomplishments in biomedical research. The volume will provide a one of a kind reference work that highlights the many efforts, from the discovery of the HCV virus, to the invention of breakthrough medicines and their use in the real world to cure patients. It is the companion book to the volume "HCV: The Journey from Discovery to a Cure - Volume II".


Malignant Lymphomas

Malignant Lymphomas

Author: Michael L. Grossbard

Publisher: PMPH-USA

Published: 2002

Total Pages: 488

ISBN-13: 9781550091526

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Malignant Lymphomas ACS American Cancer Society Atlas of Clinical Oncology Malignant Lymphomas is a volume in the acclaimed American Cancer Society Atlas of Clinical Oncology series. Dr. Grossbard and his team have summarized current knowledge on the pathology, epidemiology, molecular biology, presentation and management of ......