Introduction to Electrophysiological Methods and Instrumentation
Introduction to Electrophysiological Methods and Instrumentation

Author: Franklin Bretschneider

Publisher: Academic Press

Published: 2018-11-13

Total Pages: 372

ISBN-13: 0128142111

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Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals. - Introduces possibilities and solutions, along with the problems, pitfalls, and artefacts of equipment and electrodes - Discusses the particulars of recording from brain tissue slices, oocytes and planar bilayers - Describes optical methods pertinent to electrophysiological practice - Presents the fundamentals of signal processing of analogue signals, spike trains and single channel recordings, along with procedures for signal recording and processing - Includes appendices on electrical safety and foundations of useful mathematical tools

Basic Electrophysiological Methods
Basic Electrophysiological Methods

Author: Ellen Covey

Publisher: Oxford University Press

Published: 2015-02-25

Total Pages: 241

ISBN-13: 0199342547

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Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.

Electrophysiological Recording Techniques
Electrophysiological Recording Techniques

Author: Robert P. Vertes

Publisher: Humana Press

Published: 2010-11-19

Total Pages: 0

ISBN-13: 9781603272018

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Applying neurophysiological methods to the study of brain-behavior relationships proved to be a major advance in the early days of neuroscience research. Considerable technological progress has been made very recently, and the impact on modern neuroscience will be invaluable. In Electrophysiological Recording Techniques, experts in the field present a current view of the widespread application of electrophysiological methods to the study of the brain and to the problem of brain-behavior relationships. The book has been organized to display the range of modern neurophysiological methods ranging from the recordings of single neurons and neuronal ensembles to recordings of field potentials within discrete brain regions and across multiple brain areas. Many of the chapters also address the major challenge of applying the appropriate methods to analyze and interpret neurophysiological recording data. As a volume in the popular Neuromethods series, the chapters provide authoritative reviews of many commonly used approaches in the field today in both the basic research level and in clinical settings. Practical and up-to-date, Electrophysiological Recording Techniques serves as a key reference volume for researchers working in this ever-changing and vital field.

Principles and Practice of Clinical Electrophysiology of Vision, second edition
Principles and Practice of Clinical Electrophysiology of Vision, second edition

Author: John R. Heckenlively

Publisher: MIT Press

Published: 2006-04-07

Total Pages: 1033

ISBN-13: 0262083469

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The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

Cardiac Electrophysiology Methods and Models
Cardiac Electrophysiology Methods and Models

Author: Daniel C. Sigg

Publisher: Springer Science & Business Media

Published: 2010-09-11

Total Pages: 490

ISBN-13: 1441966587

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Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Practical Methods in Cardiovascular Research
Practical Methods in Cardiovascular Research

Author: Stefan Dhein

Publisher: Springer

Published: 2006-02-28

Total Pages: 1011

ISBN-13: 3540265740

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Scientists working or planning to work in the field of cardiovascular research will welcome Methods in Cardiovascular Research as the reference book they have been waiting for. Not only general aspects of cardiovascular research are well presented but also detailed descriptions of methods, protocols and practical examples. Written by leading scientists in their field, chapters cover classical methods such as the Langendorff heart or working heart models as well as numerous new techniques and methods. Newcomers and experienced researchers alike will benefit from the troubleshooting guide in each chapter, the extensive reference lists for advanced reading and the great practical experience of the authors. Methods in Cardiovascular Research is a "must have" for anybody with an interest in cardiovascular research.

Handbook of Cardiac Electrophysiology
Handbook of Cardiac Electrophysiology

Author: Francis D. Murgatroyd

Publisher: Remedica

Published: 2002

Total Pages: 230

ISBN-13: 1901346374

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This text is a comprehensive introductory-level guide to invasive cardiac EP studies. Its focus is to enable the reader to understand and interpret the recording and stimulation techniques used during an EP study.

Computer Analysis of Electrophysiological Signals
Computer Analysis of Electrophysiological Signals

Author: John Dempster

Publisher:

Published: 1993-01-01

Total Pages: 228

ISBN-13: 9780122089404

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A Volume in the Biological Techniques Series. This essential bench-top manual is the first comprehensive introduction to the principles and practice of the analysis of electrophysiological signals. The text describes hardware and software, including specific techniques for the analysis of single ion channels, noise analysis, and voltage-clamped whole cell currents. Rather than simply providing a manual describing how to use computer programs, this book provides insight into why programs operate in particular ways, the pitfalls awaiting the unwary, and the general philosophy behind signal analysis techniques. Examples of program source code are included. Key Features * Explains the principles of the digitization of analog signals * Provides practical examples for hardware in common use in the electrophysiological laboratory

Electrophysiological Maneuvers for Arrhythmia Analysis
Electrophysiological Maneuvers for Arrhythmia Analysis

Author: George J. Klein MD

Publisher: Cardiotext Publishing

Published: 2014-05-01

Total Pages: 211

ISBN-13: 1935395157

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From senior electrophysiologist and world-class educator George Klein, a fully illustrated guide with over 100 intracardiac tracings and figures that allow the physician to approach electrophysiologic problems effectively and systematically. The book is especially focused on electrophysiological maneuvers and provides a clear and understandable guide to their proper selection and interpretation using abundant clinical examples. Defines the integral role for "traditional" electrogram (EGM) analysis in order to understand the mechanism of a tachycardia. It goes without saying that a correct arrhythmia diagnosis is a prerequisite to catheter ablation regardless of the presence of sophisticated mapping and imaging technologies. Electrophysiological maneuvers are fundamental to this process, and proper selection and interpretation of maneuvers constitute a core skill of the electrophysiologist. In this volume, we make the case that most maneuvers are fundamentally similar in principle and can be understood by appreciating a few basic physiological and anatomical principles. The art lies not in a comprehensive knowledge by rote of every maneuver or its application, but rather a systematic approach using common principles. We illustrate this by showing abundant examples and emphasizing the "game plan," including checklists that can be applied to virtually any maneuver. —George J. Klein In my opinion, this book should be on the shelf of every electrophysiologist trainee as well as every clinical cardiac electrophysiologist. It is a classic, like its editor. Dr. Klein deserves high praise for organizing his and his colleagues’ clinical experiences and thought processes into a concise, practical text that should be part of all training programs in electrophysiology. —From the foreword by Mark E. Josephson, MD

Practical Intracardiac Echocardiography in Electrophysiology
Practical Intracardiac Echocardiography in Electrophysiology

Author: Jian-Fang Ren

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 256

ISBN-13: 0470994967

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Tremendous advances in intracardiac echocardiography (ICE) have coincided with the evolution of interventional electrophysiology. This book is designed to provide both the electrophysiologist and echocardiographer with an in-depth view of the role and value of ICE during electrophysiologic procedures. A guide to techniques used for optimal ICE imaging in cardiac electrophysiology is provided. In addition, new and less-recognized uses of ICE in electrophysiological procedures are described and their clinical applications are presented. Illustrated with over 500 images, many of which are in color, the book can also be used as a practical atlas. Readers need not be experts in the field of echocardiography to benefit from this practical approach to intracardiac imaging in electrophysiology.