Platelet-Rich Plasma
Platelet-Rich Plasma

Author: José Fábio Santos Duarte Lana

Publisher: Springer Science & Business Media

Published: 2013-10-29

Total Pages: 368

ISBN-13: 3642401171

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Platelet-Rich Plasma (PRP) has gained tremendous popularity in recent years as a treatment option for specialties including Orthopedics, Dentistry, Sports Medicine, Otorhinolaryngology, Neurosurgery, Ophthalmology, Urology, Vascular, Cardiothoracic and Maxillofacial Surgery, and Veterinarian Medicine. Nowadays, PRP and Stem Cell Science have added an exciting dimension to tissue repair. This book begins by giving the reader a broad overview of current progress as well as a discussion of the technical aspects of preparation and therapeutic use of autologous PRP. It is followed by a review of platelet structure, function and major growth factors in PRP (PDGF and TGFβ).The third chapter outlines the basic principles of biochemical cellular metabolism that increases the efficacy of PRP. Analogous to the preparation of soil for a garden, restoring cellular health should be the first consideration in Regenerative Medicine. Standardization of PRP preparation to clinical use still remains a challenging prospect. In this sense, a feasible strategy for studying PRP preparation is illustrated, which also allows to modulate and tailor the quality of PRP for further clinical applications. The science behind PRP and stem cells, on tissue regeneration, cell proliferation and mesenchyme stem-cells are emphasized and reviewed. Various specific uses of PRP are described with detailed illustrations of various personal experiences mainly in orthopedic injuries, ligament and tend on repair, degenerative diseases, sports medicine, chronic wound healing as well as rehabilitation aspects in tendinopathy. Expertly written by leading scientists in the field, this book provides for beginners and experienced readers scientific fundamentals, the state of art of PRP, specific uses and personal experiences with a practical approach and reference for current trends in use. Finally, this book paves the way for future developments.

Platelet Rich Plasma in Orthopaedics and Sports Medicine
Platelet Rich Plasma in Orthopaedics and Sports Medicine

Author: Eduardo Anitua

Publisher: Springer

Published: 2018-03-28

Total Pages: 269

ISBN-13: 3319637304

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This book provides a comprehensive, state-of-the art summary of platelet rich plasmas (PRPs) in the field of regenerative medicine. The book begins with an overview of the basic science behind PRP, describing the role of platelets and growth factors followed by the most important biological effects expected from the use of PRPs. Platelet Rich Plasma in Orthopaedics, Sports Medicine and Maxillofacial Surgery includes numerous contributions detailing the current use of PRPs in clinical practice. From the origins in oral and maxillofacial surgery, to the latest advances in orthopaedics and sports medicine including the use of Platelet Rich Growth Factors (PRGF) in muscle, bone, tendon, ligament and nerve injuries, this book provides a wide scope of the topic. The volume concludes with chapters from experts in biology, orthopaedics, oral and maxillofacial surgery, where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of PRGF. This book will provide a useful resource for physicians and researchers interested in learning more about this rapidly growing area of biomedical treatment.

Articular Cartilage
Articular Cartilage

Author: Kyriacos A. Athanasiou

Publisher: CRC Press

Published: 2013-03-21

Total Pages: 442

ISBN-13: 143985324X

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Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.

Sports Injuries
Sports Injuries

Author: Mahmut Nedim Doral

Publisher: Springer Nature

Published: 2015-06-29

Total Pages: 3295

ISBN-13: 3642365698

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Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.

Biotechnology
Biotechnology

Author: Deniz Ekinci

Publisher: BoD – Books on Demand

Published: 2015-04-15

Total Pages: 244

ISBN-13: 9535120409

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Over the recent years, biotechnology has become responsible for explaining interactions of biological tools and processes so that many scientists in the life sciences from agronomy to medicine are engaged in biotechnological research. This book contains an overview focusing on the research area of molecular biology, molecular aspects of biotechnology, synthetic biology and agricultural applications in relevant approaches. The book deals with basic issues and some of the recent developments in biotechnological applications. Particular emphasis is devoted to both theoretical and experimental aspect of modern biotechnology. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in associated areas. The book is written by international scientists with expertise in chemistry, protein biochemistry, enzymology, molecular biology and genetics, many of which are active in biochemical and biomedical research. We hope that the book will enhance the knowledge of scientists in the complexities of some biotechnological approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications.

Cosmetic Dermatology
Cosmetic Dermatology

Author: Zoe Diana Draelos

Publisher: John Wiley & Sons

Published: 2015-10-14

Total Pages: 34

ISBN-13: 111865546X

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Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Musculoskeletal Tissue Regeneration
Musculoskeletal Tissue Regeneration

Author: William S. Pietrzak

Publisher: Springer Science & Business Media

Published: 2008-04-11

Total Pages: 647

ISBN-13: 1597452394

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The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

PRP and Microneedling in Aesthetic Medicine
PRP and Microneedling in Aesthetic Medicine

Author: Amelia K. Hausauer

Publisher: Thieme

Published: 2019-05-31

Total Pages: 258

ISBN-13: 1626239053

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State-of-the-art PRP and microneedling aesthetic procedures from internationally renowned experts Platelet rich plasma (PRP) and microneedling are two increasingly popular off-label modalities intended to harness the body's self-rejuvenation and repair abilities. PRP and Microneedling in Aesthetic Medicine is the most comprehensive, clinically informed resource available today on these two techniques. Internationally renowned, minimally invasive facial aesthetics experts Amelia K. Hausauer, Derek H. Jones, and a cadre of esteemed contributors have written the definitive guide on this topic. Readers will learn how to evaluate and critically appraise various approaches and leverage evidence-based methods to guide best practices. Divided into three parts, the first chapters on PRP and microneedling lay a solid foundation, covering basic science, mechanism of action, preparation, and practical considerations. Each chapter includes in-depth discussion, technical pearls, and practical tips for incorporating specific techniques into clinical practice. Part three focuses on special topics including applications and safety in skin of color, combination therapies, and managing complications. Key Highlights Applications for PRP including chronic wound healing, scars and scar revision, aesthetic rejuvenation and augmentation, and alopecia and hair restoration Microneedling for the treatment of acne and other scars, striae, melasma and dyschromia, skin rejuvenation, hyperhidrosis, and photodamage The concurrent use of PRP and microneedling; PRP and laser resurfacing, rhitidectomy, and ultrasound; and microneedling with radiofrequency and drug-assisted delivery About 100 images elucidate impacted anatomy and techniques; and 10 short online videos provide enhanced procedural guidance This is an essential resource for practitioners and training providers in dermatology and plastic surgery, particularly those specializing in facial and oculoplastic sub-specialties. It is a must-have for all aesthetic physicians seeking to expand their repertoire of minimally invasive facial surgery approaches.

Orthobiologics
Orthobiologics

Author: Giuseppe Filardo

Publisher: Springer Nature

Published: 2021-12-02

Total Pages: 394

ISBN-13: 3030847446

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This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.