This book provides an introduction to physical chemistry that is directed toward applications to the biological sciences. Advanced mathematics is not required. This book can be used for either a one semester or two semester course, and as a reference volume by students and faculty in the biological sciences.
Physical Techniques in Biological Research, Second Edition, Volume II, Part B: Physical Chemical Techniques covers physical chemical techniques that have been most widely employed in the investigation of molecules of biological significance. The book discusses the measurement and properties of ionizing radiations; magnetic resonance and related techniques in magnetic susceptibility measurements; and chromatographic methods and applications of chromatography to steroid research. The text then describes the phenomenon of centrifugation, including the techniques for studying density gradient centrifugation; the formation of gradient column in swinging-bucket tubes; gradient materials; density gradient centrifugation in heavy salt; some factors influencing the distribution of sedimenting particles; and the recovery of samples. Biological investigators and students of biophysics or biochemistry will find the book invaluable.
This text provides detailed coverage of physical methods used in bioinorganic chemistry. By integrating theory with experimentation, and providing a more biological orientation, the book aims to serve as a major textbook for students of bioinorganic chemistry.
Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.
Physical Techniques in Biological Research, Second Edition, Volume II, Part B: Physical Chemical Techniques covers physical chemical techniques that have been most widely employed in the investigation of molecules of biological significance. The book discusses the measurement and properties of ionizing radiations; magnetic resonance and related techniques in magnetic susceptibility measurements; and chromatographic methods and applications of chromatography to steroid research. The text then describes the phenomenon of centrifugation, including the techniques for studying density gradient cent ...
Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)