Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography. - Concise overview of various chorioretinal disorders, with special emphasis on choroidal imaging - Written for practitioners and researchers in sensory systems (vision), ophthalmologists, and retina specialists - Covers the most advanced imaging techniques in choroidal disorders, such as enhanced depth imaging OCT, swept source OCT, and OCT angiography
Age-related macular degeneration (AMD) is a disease that causes loss of vision and can lead to central blindness in some patients. Loss of vision from AMD is permanent and has a significant impact on an individual's functioning and quality of life. Currently, there are no effective treatments for the majority of individuals with AMD. Verteporfin photodynamic therapy (PDT) a new treatment for "wet" AMD, the type of AMD responsible for more pronounced vision loss. Evidence from three high-quality RCTs suggests that, compared with placebo, verteporfin PDT treatment for two years reduces the number of cases of central blindness. However, these results apply to a study population with subfoveal neovascularization from AMD, and only a minority of these individuals is likely to qualify for treatment after diagnosis and angiographic assessment. Verteporfin PDT is likely to increase the need for angiographic screening. Treatment is not aimed at restoring vision and the majority of treated individuals will continue to lose visual acuity. Compared to placebo (angiography and sham treatment), verteporfin did not cause an overall increase in serious adverse events and appears to be reasonably well tolerated. The direct impact of this treatment on quality of life and visual function is not known. The two-year incremental costs for this procedure in Canada based on RCT evidence are estimated to be between $10,625 and $14,250.
Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT.
Pathologic Myopia is a major cause of severe vision loss worldwide. The mechanisms for vision loss include cataract, glaucoma, retinal detachment, and above all, myopic maculopathy within the posterior staphyloma. The first edition of Pathologic Myopia is one of the only current books to specifically address this disease and discusses recent developments in imaging technologies and various approaches to treatments, such as laser photocoagulation, photodynamic therapy, pharmaco-therapeutic injections in the vitreous, and surgery. This new edition is a timely update to the standard reference in the field, with new chapters on advanced refractive error correction, genetics, developing a classification system, and special surgical approaches for pathologic myopia. Complete with even more high-quality color images and informative tables, this book is written and edited by leaders in the field and is geared towards ophthalmologists, including residents and fellows in training, glaucoma and cataract specialists, and vitreoretinal macula experts.
Written by an international team of ophthalmic practitioners, this authoritative book is a vital resource not only for ophthalmic professionals, but for any healthcare professional who cares for patients with eye problems. In the ten years since the first edition was published, practice has moved on, as has the evidence for practice. This second edition draws on the passion and goodwill of the original team of authors, complemented by other colleagues, to fully revise and update the text in line with new findings, new practice and new and exciting treatments. The book is broadly divided into three sections. The first section considers the structure and function of the eye, as well as the basic principles of ophthalmology and eye examination. The second section considers patient care in diverse settings, as well as work-related issues and patient education. It also includes two entirely new chapters on eye banking and global eye health. The third section takes a systematic approach to patient care, working from the front to the back of the eye, discussing some of the common disorders affecting each structure (such as the lens or cornea) or group of structures (such as the eyelids or lacrimal drainage system). The book concludes with a very useful glossary of ophthalmic terms. Some aspects of practice discussed in the text are, of necessity, UK based, but these are clearly indicated and, wherever possible, principles (rather than specifics) are addressed and readers are directed to local policies and interpretations. The first edition of this book became a core text for ophthalmic nursing, in particular, and for the education of ophthalmic nurses across the world. This new edition will provide a comprehensive, up-to-date, evidence-based resource for all ophthalmic healthcare professionals. Contents include: • Physiology of vision • Optics • Pharmacology • Examination of the eye • Visual impairment • Patient education • Work and the eye • Care of the adult ophthalmic patient in an inpatient setting • The care of the child undergoing ophthalmic treatment • Developments in day care surgery for ophthalmic patients • Ophthalmic theatre nursing • The care of patients presenting with acute problems • Eye banking • Global eye health • The eyelids and lacrimal drainage system • The conjunctiva • The cornea • The sclera • The lens • The uveal tract • The angle and aqueous • The retina and vitreous • The orbit and extraocular muscles • Visual and pupillary pathways and neuro-ophthalmology • The eye and systemic disease
The book discusses all aspects of choroidal neovascularization (CNV), including the basics, clinical conditions associated with CNV, clinical trials related to CNV, future directions and rehabilitation. The first section covers the pathogenesis, proposed mechanisms, disease models, histopathology and electronmicroscopy. The next section explores CNV secondary to various clinical conditions, such as age-related macular degeneration (AMD), myopia, and less common conditions like choroidal osteoma. The book also covers clinical features, imaging characteristics, and treatment approaches, as well as clinical trials in CNV conditions with recent updates. Lastly, it features chapters on stem cell therapy, gene therapy, new molecules, and lasers, as well as a section on rehabilitation, which addresses home monitoring and low vision aids. This book is intended for retina specialists, retina fellows and general ophthalmologists.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
This is the only text available that is devoted exclusively to the ICG imaging technique, its methods and findings. It provides an invaluable guide to this new diagnostic/research tool.
