Revised and updated for the second edition, this reference volume draws on biosynthetic relationships to describe both the primary and secondary classes of matabolites and the drugs from which they originate.
Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.
This comprehensive textbook primarily aims at fulfilling the syllabus requirements of B.Pharm. students. It is specifically designed to impart knowledge about the alternative systems of medicine and modern pharmacognosy. Additionally, it will also serve as a valuable information resource to other health sciences students and researchers working in the field of herbal technology.
Medicinal Plants: Chemistry, Biology and Omics reviews the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plant tribes and genera, and their relevance to drug efficacy. Medicinal plants provide a myriad of pharmaceutically active components, which have been commonly used in traditional Chinese medicine and worldwide for thousands of years. Increasing interest in plant-based medicinal resources has led to additional discoveries of many novel compounds, in various angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology. Chapters in this book explore the interrelationship within traditional Chinese medicinal plant groups and between Chinese species and species outside of China. Chapters also discuss the incongruence between chemotaxonomy and molecular phylogeny, concluding with chapters on systems biology and "-omics technologies (genomics, transcriptomics, proteomics, and metabolomics), and how they will play an increasingly important role in future pharmaceutical research. - Reviews best practice and essential developments in medicinal plant chemistry and biology - Discusses the principles and applications of various techniques used to discover medicinal compounds - Explores the analysis and classification of novel plant-based medicinal compounds - Includes case studies on pharmaphylogeny - Compares and integrates traditional knowledge and current perception of worldwide medicinal plants
This new edition of the book by Jean Bruneton has been revised and expanded by over 200 pages, to reflect the most recent advances (natural or semisynthetic substances) as well as the most recent contributions to the therapeutic arsenal (antimalarial, antitumor, or antiretroviral agents). Building upon biosynthetic relationships, the author describes the different classes of metabolites and the drugs that produce them. Organized in four parts (primary metabolites, phenolics, shikimates and acetates, terpenes and steroids, alkaloids), the book develops for each class, phytochemical generalities, distribution, biosynthesis, extraction and quantitation methods, and biological aspects. For each raw material, it presents the origin, identity, production, composition, uses, processing and optimization: thus a considerable amount of botanical, chemical, analytical, pharmacological and therapeutic data is gathered into a particularly coherent compilation, for each product, the therapeutic indications and recommended usage are specified. An extensive index (about 3 000 entries) and nearly 500 recent references represent a valuable starting point for the reader's own lietrature research. This encyclopedia of pharmacognosy and phytochemistry is written for students, educators and professionals using plant resources in pharmacy, cosmetology, perfumery, botany, food technology and other fields.
This volume focuses on the importance of therapeutically active compounds of natural origin. Natural materials from plants, microbes, animals, marine organisms and minerals are important sources of modern drugs. Beginning with two chapters on the development and definition of the interdisciplinary field of pharmacognosy, the volume offers up-to-date information on natural and biosynthetic sources of drugs, classification of crude drugs, pharmacognosical botany, examples of medical application, WHO ́s guidelines and intellectual property rights for herbal products.
Textbook of Pharmacognosy and Phytochemistry This comprehensive textbook is primarily aimed at the course requirements of the B. Pharm. students. This book is specially designed to impart knowledge alternative systems of medicine as well as modern pharmacognosy. It would also serve as a valuable resource of information to other allied botanical and alternative healthcare science students as well as researchers and industrialists working in the field of herbal technology. Only Textbook Offering... Recent data on trade of Indian medicinal plants (till 2008) Illustrated biosynthetic pathways of metabolites as well as extraction and isolation methodologies of medicinal compounds Bioactivity determination and synthesis of herbal products of human interest Information on Ayurvedic plants and Chinese system of medicine Simple narrative text that will help the students quickly understand important concepts Over 300 illustrations and 120 tables in order to help students memorize and recall vital concepts making this book a student’s companion cum teacher A must buy for every student of pharmacognosy!
Pengelly's user friendly text will encourage educators in medical science to consider using this material in the complementary medicine/nutraceuticals areas May I congratulate Andrew Pengelly for writing this text as it is going to be very popular with undergraduate students as well as more experienced readers.' D. Green, London Metropolitan University, UK This unique book explains in simple terms the commonly occurring chemical constituents of medicinal plants. The major classes of plant constituents such as phenols, terpenes and polysaccharides, are described both in terms of their chemical structures and their pharmacological activities. Identifying specific chemical compounds provides insights into traditional and clinical use of these herbs, as well as potential for adverse reactions. Features include: * Over 100 diagrams of chemical structures * References to original research studies and clinical trials * References to plants commonly used throughout Europe, North America and Australasia. Written by an experienced herbal practitioner, The Constituents of Medicinal Plants seriously challenges any suggestion that herbal medicine remains untested and unproven, including as it does hundreds of references to original research studies and trials. Designed as an undergraduate text, the first edition of this book became an essential desktop reference for health practitioners, lecturers, researchers, producers and anyone with an interest in how medicinal herbs work. This edition has been extensively revised to incorporate up-to-date research and additional sections, including an expanded introduction to plant molecular structures, and is destined to become a classic in the literature of herbal medicine.
This book details several important medicinal plants, their occurrence, plant compounds and their chemical structures, and pharmacological properties against various human diseases. It also gives information on isolation and structural elucidation of phytocompounds, bio-assays, metabolomic studies, and therapeutical applications of plant compounds.
This unique book is a collaborative effort between researchers at Rutgers University and colleagues from numerous institutions in Uzbekistan and Kyrgyzstan. It will be the first book to document more than 200 of the most important medicinal plants of Central Asia, many whose medicinal uses and activities are being described in English for the first time. The majority of the plants described grow wild in Central Asia with some being endemic, while other species have been introduced to Central Asia but are commonly used in regional plant based medicine. The book contains four introductory chapters. The first and second chapters cover the geography, climate and vegetation of Kyrgyzstan and Uzbekistan, respectively. The third chapter provides a brief history of medicinal plant use and science in Central Asia and the fourth chapter contains general information about phytochemistry. The fifth chapter comprises the bulk of the book and covers 208 medicinal plant species. Nearly all species have one or more high quality, color photographs. Three useful appendices have been included. The first is a glossary of botanical and ecological terms, the second is a glossary of chemistry terms and the third is a glossary of medical terms. During the preparation of this manuscript we found there to be a deficiency in quality reference resources for the translation of many of the technical terms associated with the different branches of science covered in this book. In order to make our job easier we compiled glossaries over the course of preparing the manuscript and have included them feeling that they will be an extremely valuable resource for readers.