Advances and Challenges in Pharmaceutical Technology
Advances and Challenges in Pharmaceutical Technology

Author: Amit Kumar Nayak

Publisher: Academic Press

Published: 2021-02-09

Total Pages: 572

ISBN-13: 0128203005

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Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. - Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology - Includes contributions from global leaders and experts in academia, industry and regulatory agencies - Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Current Research in Pharmaceutical Technology
Current Research in Pharmaceutical Technology

Author: Sabine Globig

Publisher: CRC Press

Published: 2011-12-15

Total Pages: 296

ISBN-13: 1926692683

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Pharmaceutical technology deals with the discovery, production, processing, and safe and effective delivery of medications to patients. Technologies involved include computer modeling for research, bioengineering for research instrumentation, processes and methods for increasing production, and computing technology and biosystematics for the management and analysis of data. This new book covers a wide range of important topics on today’s pharmaceutical technology, such as in vitro drug release and controlled drug delivery, the use of nanotechnology in pharmaceuticals, quantum dot imaging, assessment and efficacy of pharmaceuticals, and much more.

Pharmaceutical Technology: Concepts and applications
Pharmaceutical Technology: Concepts and applications

Author: S. Bharath

Publisher: Pearson Education India

Published: 2013

Total Pages: 345

ISBN-13: 9332520240

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Pharmaceutical Technology – Concepts and Applications articulates on the various pharmaco-technological concepts associated with industrial pharmacy. The book not only focuses on providing comprehensive information on formulation development and affiliated areas but also emphasizes on their industrial applications. With a plethora of examples that illustrate important concepts, the book equips students of pharmacy to rise to the requirements of the industry.

Pharmaceutical Technology And Process
Pharmaceutical Technology And Process

Author: Dr. Abhinandan Ravsaheb Patil

Publisher: AG Publishing House (AGPH Books)

Published: 2022-09-12

Total Pages: 224

ISBN-13: 9395468807

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Recent materials, process development, and drug delivery strategies are explored through the Challenges faced by Pharmaceutical Technology. Techniques for the statistical formulation optimization, the Quality by design along with process analytical technologies, and the use of a wide range of pharmaceutical biomaterials—from natural polymers and synthetic polymers to modified-natural polymers, bioceramics, as well as other bioinorganica—are all covered in detail. As the area of pharmaceuticals continues to expand at a fast pace, this book provides a comprehensive overview of the procedures, formulation innovations, investigations, and exploitation of pharmaceutical biomaterials used in the production of pharmacological dosage forms. From the first stages of medication development to production, methods and technology, rules and regulations, and finally, marketing, this book covers it all. Everything an undergraduate student of pharmacy or pharmaceutical sciences needs to know about pharmaceuticals is covered in this book, from active pharmaceutical components through the manufacture of different dosage forms and the associated chemistry. This book details the process through which a certain medicine was developed, tested, and ultimately brought to market. It describes all drugs that are discovered, how they work, the challenges of experimenting with them, why different dosages work, how quality is ensured, and the responsibilities of regulatory organizations. Quality assurance, product security, medicine counterfeiting and misuse, and pharmaceuticals' potential for the future are all discussed in depth.

Pharmaceutical Process Development
Pharmaceutical Process Development

Author: John Blacker

Publisher: Royal Society of Chemistry

Published: 2011-08-17

Total Pages: 375

ISBN-13: 1849733074

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Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.

Continuous Manufacturing of Pharmaceuticals
Continuous Manufacturing of Pharmaceuticals

Author: Peter Kleinebudde

Publisher: John Wiley & Sons

Published: 2017-09-05

Total Pages: 645

ISBN-13: 1119001323

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A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.

Voigt's Pharmaceutical Technology
Voigt's Pharmaceutical Technology

Author: Alfred Fahr

Publisher: John Wiley & Sons

Published: 2018-01-17

Total Pages: 885

ISBN-13: 1118972430

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A textbook which is both comprehensive and comprehensible and that offers easy but scientifically sound reading to both students and professionals Now in its 12th edition in its native German, Voigt's Pharmaceutical Technology is an interdisciplinary textbook covering the fundamental principles of pharmaceutical technology. Available for the first time in English, this edition is produced in full colour throughout, with a concise, clear structure developed after consultation with students, instructors and researchers. This book: Features clear chapter layouts and easily digestible content Presents novel trends, devices and processes Discusses classical and modern manufacturing processes Covers all formulation principles including tablets, ointments, capsules, nanosystems and biopharmaceutics Takes account of legal requirements for both qualitative and quantitative composition Addresses quality assurance considerations Uniquely relates contrasting international pharmacopeia from EU, US and Japan to formulation principles Includes examples and text boxes for quicker data assimilation Written for both students studying pharmacy and industry professionals in the field as well as toxicologists, biochemists, medical lab technicians, Voigt’s Pharmaceutical Technology is the essential resource for understanding the various aspects of pharmaceutical technology.

Process Analytical Technology
Process Analytical Technology

Author: Katherine A. Bakeev

Publisher: John Wiley & Sons

Published: 2010-04-01

Total Pages: 576

ISBN-13: 0470689609

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Process Analytical Technology explores the concepts of PAT and its application in the chemical and pharmaceutical industry from the point of view of the analytical chemist. In this new edition all of the original chapters have been updated and revised, and new chapters covering the important topics of sampling, NMR, fluorescence, and acoustic chemometrics have been added. Coverage includes: Implementation of Process Analytical Technologies UV-Visible Spectroscopy for On-line Analysis Infrared Spectroscopy for Process Analytical Applications Process Raman Spectroscopy Process NMR Spectrscopy: Technology and On-line Applications Fluorescent Sensing and Process Analytical Applications Chemometrics in Process Analytical Technology (PAT) On-Line PAT Applications of Spectroscopy in the Pharmaceutical Industry Future Trends for PAT for Increased Process Understanding and Growing Applications in Biomanufacturing NIR Chemical Imaging This volume is an important starting point for anyone wanting to implement PAT and is intended not only to assist a newcomer to the field but also to provide up-to-date information for those who practice process analytical chemistry and PAT. It is relevant for chemists, chemical and process engineers, and analytical chemists working on process development, scale-up and production in the pharmaceutical, fine and specialty chemicals industries, as well as for academic chemistry, chemical engineering, chemometrics and pharmaceutical science research groups focussing on PAT. Review from the First Edition “The book provides an excellent first port of call for anyone seeking material and discussions to understand the area better. It deserves to be found in every library that serves those who are active in the field of Process Analytical Technology.”—Current Engineering Practice

Pharmaceutical Extrusion Technology
Pharmaceutical Extrusion Technology

Author: Isaac Ghebre-Selassie

Publisher: CRC Press

Published: 2003-05-14

Total Pages: 383

ISBN-13: 0824755200

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Pharmaceutical Extrusion Technology is the only resource to provide in-depth descriptions and analyses of the key parameters of extruders and extrusion processes. The book highlights the applicability of melt extrusion in pharmaceutical drug development and product manufacturing, including controlled release, dissolution rate and bioavailability enhancement, and granulation technology. It brings together the technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements and details extruder hardware and controls, process definition and troubleshooting of single and twin screw extrusion processes, and more.

Encyclopedia of Pharmaceutical Technology
Encyclopedia of Pharmaceutical Technology

Author:

Publisher:

Published: 1988

Total Pages:

ISBN-13:

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Covers the discovery development,regulation, manufacturing, and commercialization of drugs and dosage forms. Includes pharmaceuticals,pharmacokinetics, analytical chemistry, quality assurance, toxicology and the manufacturing process.