Perspectives In Human Biology: Genes, Ethnicity And Ageing
Perspectives In Human Biology: Genes, Ethnicity And Ageing

Author: Linc H Schmitt

Publisher: World Scientific

Published: 1995-11-27

Total Pages: 109

ISBN-13: 9814499390

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This volume takes its subtitle from the theme of the ASHB meeting for 1994 “Genes, Ethnicity and Ageing”. The first paper is the annual conference lecture as delivered by the Honourable Fred Chaney, formerly Minister for Aboriginal Affairs in the Federal Government of Australia. It considers some of the difficulties in delivering government services to indigenous peoples. Jim Chisholm puts an evolutionary perspective on some aspects of human behaviour, life history and Darwinian approaches to medicine. Carol Bower reviews the value of the Western Australian Birth Defects Registry and the contributions of registries to improved health care. Alexandra Brewis and Gokarna Regmi document determinants of fertility in a Pacific Island population. There are two papers from a special symposium on Ageing and the Aged held within the meeting: George Broe and Helen Creasey consider some of the social issues associated with an ageing society, and Alan Hipkiss and colleagues take a biochemist's look at possibilities for extending the human life cycle.There are two additional papers. One by Alan Bittles documents consanguinity in the Middle East. The second, by Tsunehiko Hanihara and Hajime Ishida describes the results of their studies of Australian Aboriginals and neighbouring populations.“Understanding Ageing”, by Robin Holliday, Cambridge University Press is reviewed by Anne Mitchell.

Genes, Ethnicity, and Ageing
Genes, Ethnicity, and Ageing

Author: Lincoln Heinze Schmitt

Publisher: World Scientific

Published: 1995

Total Pages: 116

ISBN-13: 9789810225513

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This volume takes its subtitle from the theme of the ASHB meeting for 1994 ?Genes, Ethnicity and Ageing?. The first paper is the annual conference lecture as delivered by the Honourable Fred Chaney, formerly Minister for Aboriginal Affairs in the Federal Government of Australia. It considers some of the difficulties in delivering government services to indigenous peoples. Jim Chisholm puts an evolutionary perspective on some aspects of human behaviour, life history and Darwinian approaches to medicine. Carol Bower reviews the value of the Western Australian Birth Defects Registry and the contributions of registries to improved health care. Alexandra Brewis and Gokarna Regmi document determinants of fertility in a Pacific Island population. There are two papers from a special symposium on Ageing and the Aged held within the meeting: George Broe and Helen Creasey consider some of the social issues associated with an ageing society, and Alan Hipkiss and colleagues take a biochemist's look at possibilities for extending the human life cycle.There are two additional papers. One by Alan Bittles documents consanguinity in the Middle East. The second, by Tsunehiko Hanihara and Hajime Ishida describes the results of their studies of Australian Aboriginals and neighbouring populations.?Understanding Ageing?, by Robin Holliday, Cambridge University Press is reviewed by Anne Mitchell.

Understanding Racial and Ethnic Differences in Health in Late Life
Understanding Racial and Ethnic Differences in Health in Late Life

Author: National Research Council

Publisher: National Academies Press

Published: 2004-09-08

Total Pages: 184

ISBN-13: 0309165865

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As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.

In the Light of Evolution
In the Light of Evolution

Author: National Academy of Sciences

Publisher:

Published: 2007

Total Pages: 388

ISBN-13:

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The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Epigenetics of Aging
Epigenetics of Aging

Author: Trygve O. Tollefsbol

Publisher: Springer Science & Business Media

Published: 2009-11-11

Total Pages: 462

ISBN-13: 1441906398

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Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Ageless Quest
Ageless Quest

Author: Leonard Guarente

Publisher: CSHL Press

Published: 2003

Total Pages: 172

ISBN-13: 9780879696528

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Ageless Questis a personal, sometimes controversial, account of the pursuit of a genetic †̃cure' for aging by an expert in the field. The author is the Novartis Professor of Biology at the Massachusetts Institute of Technology. Aging has always been regarded as a highly complex process with many degenerative changes leading to the cessation of life. But recent research has identified a relatively simple mechanism that governs the pace of aging. Lenny Guarente's Ageless Questis a scientific detective story for the baby boom generation. It offers an insider's view of an area of potentially astonishing high reward—and equally high risk.

The Gerontological Imagination
The Gerontological Imagination

Author: Kenneth F. Ferraro

Publisher: Oxford University Press

Published: 2018

Total Pages: 225

ISBN-13: 0190665343

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The power of the gerontological imagination -- Causality -- Life course analysis -- Multifaceted change -- Heterogeneity -- Accumulation process -- Ageism -- The gerontological imagination at work in scientific communities

Critical Perspectives on Racial and Ethnic Differences in Health in Late Life
Critical Perspectives on Racial and Ethnic Differences in Health in Late Life

Author: National Research Council

Publisher: National Academies Press

Published: 2004-10-16

Total Pages: 753

ISBN-13: 0309092116

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In their later years, Americans of different racial and ethnic backgrounds are not in equally good-or equally poor-health. There is wide variation, but on average older Whites are healthier than older Blacks and tend to outlive them. But Whites tend to be in poorer health than Hispanics and Asian Americans. This volume documents the differentials and considers possible explanations. Selection processes play a role: selective migration, for instance, or selective survival to advanced ages. Health differentials originate early in life, possibly even before birth, and are affected by events and experiences throughout the life course. Differences in socioeconomic status, risk behavior, social relations, and health care all play a role. Separate chapters consider the contribution of such factors and the biopsychosocial mechanisms that link them to health. This volume provides the empirical evidence for the research agenda provided in the separate report of the Panel on Race, Ethnicity, and Health in Later Life.

Human Adaptability: Future Trends And Lessons From The Past, Perspective In Human Biology, Vol 3
Human Adaptability: Future Trends And Lessons From The Past, Perspective In Human Biology, Vol 3

Author: Charles Oxnard

Publisher: World Scientific

Published: 1998-01-22

Total Pages: 128

ISBN-13: 9814496561

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This volume takes its subtitle from the theme of the ASHB meeting for 1996 “Human Adaptibility: Future Trends and Lessons from the Past”. The first paper is the annual conference lecture ‘Human Evolution Today: Which Way Next?’ delivered by Professor Maciej Hennenberg, the newly appointed Wood Jones Professor at the University of Adelaide. This is followed by the transcripts of two papers resulting from a debate on ‘Species and Human Evolution,’ also from the meeting. The first is ‘Species Concept in Palaeoanthropology’ by Colin Groves and the second, ‘The Problem of Species in Hominid Evolution’ by Maciej Hennenberg.There are also a series of individual papers. Two of these are shorter integrative pieces: ‘Philosophical Problems in Palaeoanthropology’ by Darren Curnoe, and ‘A Biological Basis for Generative Learning in Science’ by Lynette Schavieren and Mark Cosgrove.These are followed in turn by two proffered papers on specific problems: ‘Patterns of Morphological Discrimination in the Human Talus: a Consideration of the Case for Negative Function’, by Robert Kidd and Charles Oxnard, and ‘The Specific Status of a new Siwalik Sivapithecine Specimen’ by David Cameron, Rajeev Patnaik and Michelle Stevens.The final contribution is one of the longer integrative papers which has characterised each of the prior volumes: ‘The Interface of Function, Genes, Development and Evolution: Insights from Primate Morphometrics’ by Charles Oxnard.