Therapy for Ocular Angiogenesis
Therapy for Ocular Angiogenesis

Author: Arup Das

Publisher: Lippincott Williams & Wilkins

Published: 2012-03-28

Total Pages: 896

ISBN-13: 1451148313

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Ocular angiogenesis, or the abnormal growth of blood vessels in the eye, is the cause of major neovascular eye diseases. With the new era of anti-angiogenic therapies, ophthalmologists have started treating many ocular diseases including macular degeneration, diabetic retinopathy, and retinal vascular occlusion using anti-angiogenic drugs. This book covers the basic pathophysiology of ocular angiogenesis and strategies for inhibition. The authors discuss the "Principles" of anti-angiogenic therapy, pre-clinical studies, future drugs on the horizon, drug delivery, and the "Practice" of the therapy in many ocular diseases. The book also includes chapters on diabetic macular edema, and various therapeutic options for this condition. A companion website includes the fully searchable text and an image bank.

Ocular Angiogenesis
Ocular Angiogenesis

Author: Joyce Tombran-Tink

Publisher: Springer Science & Business Media

Published: 2007-11-06

Total Pages: 409

ISBN-13: 1597450472

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Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

Advances in Vision Research, Volume III
Advances in Vision Research, Volume III

Author: Gyan Prakash

Publisher: Springer Nature

Published: 2021-02-18

Total Pages: 478

ISBN-13: 9811591849

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This third volume, with three supporting editors, broadens its focus on genetic eye research from the Asian to the global scale. New efforts and a new awareness have sparked important discussions on genetic eye research, and new plans are being implemented to identify the genes responsible for numerous eye diseases. The book introduces the latest findings on genetics in eye diseases, gene therapy, and genome-wide association analysis, and the efforts of the Global Eye Genetic Consortium (GEGC). The book’s editors have been instrumental in developing strategies for discovering the new genes involved in many eye diseases. All chapters were written by leading researchers working on eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume III is a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases around the globe.

Corneal Angiogenesis
Corneal Angiogenesis

Author: Gordon K. Klintworth

Publisher: Springer

Published: 2011-09-22

Total Pages: 135

ISBN-13: 9781461277873

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In this research monograph, the noted scholar Dr. Gordon K. Klintworth brings together all the available information on the pathogenesis of corneal neovascularization. This book should be a valuable contribution to the medical literature of ophthalmology and clinical pathology. Despite its relatively simple structure the cornea possesses many unique properties. These attributes include its crystal clarity and avascularity in the health state. This normally transparent structure has been the focal point for Dr. Klintworth's research endeavors for more than two decades. This monograph summarizes current knowledge about angiogenesis within this tissue as well as information about the related issue of the cornea's normal avascularity. The text provides a comprehensive overview of the topic based on studies by a large number of investigators who were either concerned with corneal neovascularization in particular or angiogenesis in general.

Anti-Angiogenic Therapy in Ophthalmology
Anti-Angiogenic Therapy in Ophthalmology

Author: Andreas Stahl

Publisher: Springer

Published: 2016-05-13

Total Pages: 198

ISBN-13: 3319240978

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This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.

Retinal and Choroidal Angiogenesis
Retinal and Choroidal Angiogenesis

Author: John Penn

Publisher: Springer Science & Business Media

Published: 2008-01-19

Total Pages: 567

ISBN-13: 1402067801

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This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.

Physiologic and Pathologic Angiogenesis
Physiologic and Pathologic Angiogenesis

Author: Dan Simionescu

Publisher: BoD – Books on Demand

Published: 2017-04-05

Total Pages: 466

ISBN-13: 9535130234

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The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Macular Dystrophies
Macular Dystrophies

Author: Giuseppe Querques

Publisher: Springer

Published: 2016-02-15

Total Pages: 128

ISBN-13: 3319266217

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​This book provides the ophthalmologist with the most recently available data on the macular dystrophies, a group of many different inherited or sporadic eye conditions linked by a problem with photoreceptors or other structures of the central retina. Internationally recognized experts in the field present the latest evidence and discuss their own personal experiences with regard to each of the principal dystrophies as well as some very rare entities. Topics covered include molecular biology, state-of-the-art diagnostic techniques, and the newest treatment options, including still experimental therapies. Attention is also devoted to a range of issues that continue to be debated. The editors have taken care to ensure that chapters are of a uniformly high standard while not sacrificing the originality of the individual authors. Macular Dystrophies will fully acquaint the reader with both the latest research findings and the current and emerging approaches to diagnosis and treatment.

Ocular Drug Delivery: Advances, Challenges and Applications
Ocular Drug Delivery: Advances, Challenges and Applications

Author: Richard T. Addo

Publisher: Springer

Published: 2016-11-16

Total Pages: 190

ISBN-13: 3319476912

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The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Angiogenesis
Angiogenesis

Author: Napoleone Ferrara

Publisher: CRC Press

Published: 2006-08-15

Total Pages: 304

ISBN-13: 1420004379

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Why a new book on angiogenesis and why now? For the first time concepts proposed over 30 years ago have found clinical validation. In the last two years the first antiangiogenic agents have been approved by the FDA for the treatment of cancer and age-related macular degeneration. Not surprisingly, this clinical success has raised a new set of basic