Patient Specific Bone Remodeling and Finite Element Analysis of the Lumbar Spine

Patient Specific Bone Remodeling and Finite Element Analysis of the Lumbar Spine

Author: Ferris M. Pfeiffer

Publisher:

Published: 2007

Total Pages:

ISBN-13:

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The body of work outlined here relates generally to mechanical engineering research in the area of biomechanics. More specifically this work focuses on numerical evaluation of lumbar spine mechanics and bone reactions as they relate to patient specific computer models. Much of this work is accomplished through the use of finite element (FE) modeling. The work is driven by the desire of surgeons to answer biomechanical and physiological questions about patient response to treatment in a noninvasive way. This work is also motivated by the need of researchers to improve upon current solution techniques to the equations of bone remodeling. The objectives of this work are to develop patient specific finite element models of patient anatomy so that patient variation can be examined, adapt current bone remodeling algorithms to address the motivation of the current study, simulate bone remodeling that occurs in the facet joint post operative to spinal fusion surgery, and to evaluate vascularization effects on bone graft growth.


Finite Element Method and Medical Imaging Techniques in Bone Biomechanics

Finite Element Method and Medical Imaging Techniques in Bone Biomechanics

Author: Rabeb Ben Kahla

Publisher: John Wiley & Sons

Published: 2020-01-02

Total Pages: 200

ISBN-13: 1786305186

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Digital models based on data from medical images have recently become widespread in the field of biomechanics. This book summarizes medical imaging techniques and processing procedures, both of which are necessary for creating bone models with finite element methods. Chapter 1 introduces the main principles and the application of the most commonly used medical imaging techniques. Chapter 2 describes the major methods and steps of medical image analysis and processing. Chapter 3 presents a brief review of recent studies on reconstructed finite element bone models, based on medical images. Finally, Chapter 4 reveals the digital results obtained for the main bone sites that have been targeted by finite element modeling in recent years.


Elastic Properties of the Human Femur

Elastic Properties of the Human Femur

Author: Annette Bretin

Publisher:

Published: 2019-02-04

Total Pages: 242

ISBN-13: 9783945954553

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Patient-specific finite element modelling of bone is a promising method for surgical planning, implant design and the prediction of bone remodelling or fracture risks, yet the assignment of material properties is challenging. Bone is a complicated structure with direction-dependent, inhomogeneous material properties, influenced by compositional, geometrical and architectural aspects. This volume focuses on a density-based assignment of orthotropic bone properties. Elasticity-density relationships in homogenized femoral zones were examined to evaluate the orthotropic density-dependence of the nine elastic material constants locally. Cortical bone samples were tested in compression and torsion tests using videoextensometry to determine the elastic constants. The elastic properties of cancellous bone were predicted by micro finite element analysis. All determined constants were correlated to the radiological bone mineral density of each sample, which was determined by quantitative computed tomography. The trabecular eigensystem was investigated for each cancellous zone to assign the mean directionality of trabecular fabric. The results can be beneficial for density-based orthotropic material assignment in femoral patient-specific finite element models.


Patient-Specific Modeling in Tomorrow's Medicine

Patient-Specific Modeling in Tomorrow's Medicine

Author: Amit Gefen

Publisher: Springer Science & Business Media

Published: 2012-01-05

Total Pages: 524

ISBN-13: 3642246176

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This book reviews the frontier of research and clinical applications of Patient Specific Modeling, and provides a state-of-the-art update as well as perspectives on future directions in this exciting field. The book is useful for medical physicists, biomedical engineers and other engineers who are interested in the science and technology aspects of Patient Specific Modeling, as well as for radiologists and other medical specialists who wish to be updated about the state of implementation.


Encyclopedia of Biomaterials and Biomedical Engineering

Encyclopedia of Biomaterials and Biomedical Engineering

Author: Gary Wnek

Publisher: CRC Press

Published: 2008-05-28

Total Pages: 3145

ISBN-13: 1498761437

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Written by more than 400 subject experts representing diverse academic and applied domains, this multidisciplinary resource surveys the vanguard of biomaterials and biomedical engineering technologies utilizing biomaterials that lead to quality-of-life improvements. Building on traditional engineering principles, it serves to bridge advances in materials science, life sciences, nanotechnology, and cell biology to innovations in solving medical problems with applications in tissue engineering, prosthetics, drug delivery, biosensors, and medical devices. In nearly 300 entries, this four-volume Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition, covers: essential topics integral to tissue engineering research: bioreactors, scaffolding materials and fabrication, tissue mechanics, cellular interaction, and development of major tissues and organs being attempted by researchers worldwide; artificial lungs and muscles, bio-artificial livers, and corneal, dental, inner ear, and total hip implants; tissue engineering of blood vessels, heart valves, ligaments, microvascular networks, skeletal muscle, and skin; bone remodeling, bone cement, and bioabsorbable bone plates and screws; controlled drug delivery, insulin delivery, and transdermal and ocular implant-based drug delivery; endovascular stent grafts, vascular grafts, and xenografts; 3-D medical imaging, electrical impedance imaging, and intravascular ultrasound; biomedical, protein adsorption, and in vivo cardiovascular modeling; polymer foams, biofunctional and conductive polymers, and electroactive polymeric materials; blood–material interactions, the bone–implant interface, host reactions, and foreign body responses and much more.


Spinal Instability

Spinal Instability

Author: Robert N.N. Holtzman

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 537

ISBN-13: 1461393264

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In this volume, world authorities on spinal surgery from the fields of Neurosurgery, Orthopaedic Surgery, and Neuroscience present current data on the basic science and clinical management of the unstable spine. Unique to this book: a frank presentation of controversies in the field.