Pathway Design for Industrial Fermentation
Pathway Design for Industrial Fermentation

Author: Walter Koch

Publisher: John Wiley & Sons

Published: 2024-01-16

Total Pages: 501

ISBN-13: 3527352759

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Pathway Design for Industrial Fermentation Explore the industrial fermentation processes of chemical intermediates In Pathway Design for Industrial Fermentation, distinguished researcher Dr. Walter Koch delivers an expert overview on industrial fermentation production technology as compared with natural extraction, organic chemistry, and biocatalysis. The book offers key insights for professionals designing and monitoring fermentation processes. The author explores the applications, alternative production, biochemical pathways, metabolic engineering strategy, and downstream processing of various products—including C1 to C6 products—with a focus on low-value products with market prices below 4€ per kilogram. Products will include methane, ethane, acetate, lactic acid, alanine, and others. With specific commentary and insightful perspectives on the cost drivers and technological aspects critical to commercially successful applications, the book also includes: Thorough introductions to methane, ethanol, acetate, lactic acid, alanine, and 3-Hydroxypropionic acid Comprehensive explorations of 1,3-Propanediol, butanol, isobutanol, and isobutene Practical discussions of 1,4-butanediol, succinic acid, itaconic acid, and glutamic acid Fulsome treatments of isoprene, pentamethylenediamine, lysine, citric acid, and adipic acid Perfect for process engineers, biotechnologists, and chemical engineers, Pathway Design for Industrial Fermentation will also benefit biochemists and professionals working in the chemical and food industries.

Industrialization of Biology
Industrialization of Biology

Author: National Research Council

Publisher: National Academies Press

Published: 2015-06-29

Total Pages: 158

ISBN-13: 0309316553

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The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

The Oxford Handbook of Food Fermentations
The Oxford Handbook of Food Fermentations

Author: Charles W. Bamforth

Publisher: Oxford Handbooks

Published: 2014

Total Pages: 833

ISBN-13: 0199742707

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Fermentation, as a chemical and biological process, is everywhere. Countless societies throughout history have used it to form a vast array of foods and drinks, many of which were integral and essential to those cultures; it could be argued that the production of beer and bread formed the basis of many agriculture-based civilizations. Today, nearly every person on the planet consumes fermented products, from beer and wine, to bread and dairy products, to certain types of meat and fish. Fermentation is a nearly ubiquitous process in today's food science, and an aspect of chemistry truly worth understanding more fully. In The Oxford Handbook of Food Fermentations, Charles W. Bamforth and Robert E. Ward have collected and edited contributions from many of the world's experts on food fermentation, each focused on a different fermentation product. The volume contains authoritative accounts on fermented beverages, distilled beverages, and a diverse set of foods, as well as chapters on relevant biotechnology. Each chapter embraces the nature of the product, its production, and its final composition. The text also touches on the raw materials and processes involved in producing packaged foodstuff, and the likely future trends in each area. In the conclusion, Bamforth and Ward present a comparison between the various products and the diverse technologies employed to produce them. Fermentation is a multifaceted process that affects a wide variety of products we consume, and The Oxford Handbook of Food Fermentations is the definitive resource that captures the science behind fermentation, as well as its diverse applications.

Industrial Microbiology
Industrial Microbiology

Author: David B. Wilson

Publisher: John Wiley & Sons

Published: 2020-03-09

Total Pages: 418

ISBN-13: 3527340351

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Focusing on current and future uses of microbes as production organisms, this practice-oriented textbook complements traditional texts on microbiology and biotechnology. The editors have brought together leading researchers and professionals from the entire field of industrial microbiology and together they adopt a modern approach to a well-known subject. Following a brief introduction to the technology of microbial processes, the twelve most important application areas for microbial technology are described, from crude bulk chemicals to such highly refined biomolecules as enzymes and antibodies, to the use of microbes in the leaching of minerals and for the treatment of municipal and industrial waste. In line with their application-oriented topic, the authors focus on the "translation" of basic research into industrial processes and cite numerous successful examples. The result is a first-hand account of the state of the industry and the future potential for microbes in industrial processes. Interested students of biotechnology, bioengineering, microbiology and related disciplines will find this a highly useful and much consulted companion, while instructors can use the case studies and examples to add value to their teaching.

Industrial Biorenewables
Industrial Biorenewables

Author: Pablo Domínguez de María

Publisher: John Wiley & Sons

Published: 2016-05-20

Total Pages: 576

ISBN-13: 111884422X

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This book provides a state-of-the-art perspective on industrial biorenewables. A selection of industries dealing with biomass as raw materials present their activities and industrial processes. Emphasis on each chapter includes, and is not limited to: discussion of the motivation of that specific industry to use biorenewables; a short history of their expertise and developments in the field; selected current R&D activities using biomass, the aim of the research, type of biomass used, catalysts, achieved products, economics, etc.; detailed discussions of the type of biomass, indicating 1st or 2nd generation, and options to substitute 1st generation raw materials for more sustainable 2nd generation ones; current processes that have been or are about to be implemented at industrial and commercial scales; expectations such as where potential improvements could be made and where academic research groups could help provide pre-competitive and industrially-sound insights and research; and finally, conclusions, prospects, and recommendations for future directions of research.

Microbial Bioprocesses
Microbial Bioprocesses

Author: Pratyoosh Shukla

Publisher: Elsevier

Published: 2023-04-20

Total Pages: 392

ISBN-13: 0323953336

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Microbial processes are involved in food, chemical, pharmaceutical, cosmetics, energy, and new-material industries. Over the past 2 decades, new or more efficient industrial processes involving microorganisms have been launched, yielding purer, less expensive products or substances not available using classical chemical methods. Microbial Bioprocesses aims to give an overview of established and successful processes and discusses the trends and perspectives in industrial microbiology which, along with tremendous progress in genetic and metabolic engineering in recent years, are once again becoming an area of innovation and emerging technologies. Microbial Bioprocesses covers the unique areas like microbial volatiles (MVOCs), microbial bioinoculant development, bacterial nanocelluloses production, and processes for remediation by fungi and actinobacteria. - Provides an innovative description of emerging bioprocesses for biotechnological gains - Provides a broad cross section of microbial bioprocess that covers several sustainability applications - Gives general insights about how microorganisms can be utilized in production of various chemicals

Advances in Yeast Biotechnology for Biofuels and Sustainability
Advances in Yeast Biotechnology for Biofuels and Sustainability

Author: Achlesh Daverey

Publisher: Elsevier

Published: 2023-05-23

Total Pages: 630

ISBN-13: 0323954502

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Advances in Yeast Biotechnology for Biofuels and Sustainability: Value-Added Products and Environmental Remediation Applications showcases the uses for engineered yeast in environmental applications, especially as an innovative source of biofuels. Beginning with a thorough review of recent advances and future potential for yeast biotechnology, the book proceeds to outline several options for biofuels, including lignocellulosic biofuels and alternative feedstock production through hydrolysis and alternative value-added products, including industrial acids and bioplastics and applications in agriculture and environmental remediation. Placing case studies at the center of each chapter, this book presents a future-focused perspective on the potential of yeast biotechnologies to support sustainability. - Lays out methods, including multiple options for generating biofuels from engineered yeast and several additional value-added products - Presents a wide variety of real-world sustainable applications for engineered yeast, with a focus on biofuels production - Provides a selection of case studies in other value-added products and applications, including bioremediation, pollution remediation, and biofertilizers in sustainable agriculture

Biomanufacturing for Sustainable Production of Biomolecules
Biomanufacturing for Sustainable Production of Biomolecules

Author: Vijai Singh

Publisher: Springer Nature

Published: 2023-01-26

Total Pages: 368

ISBN-13: 9811979111

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This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules. ​This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.

Synthetic biology applications in industrial microbiology
Synthetic biology applications in industrial microbiology

Author: Weiwen Zhang

Publisher: Frontiers E-books

Published: 2014-12-03

Total Pages: 130

ISBN-13: 288919342X

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Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.

Industrial Biotechnology
Industrial Biotechnology

Author: Christoph Wittmann

Publisher: John Wiley & Sons

Published: 2017-03-15

Total Pages: 862

ISBN-13: 3527807802

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The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.