This book is an original text written in Chinese for Paradigm Publications and translated to English. The text is drawn from many classical texts to reinforce the primary material. The Pathomechanisms series offers an in-depth analysis of the origins and disease progression for each of the zang organs of the body. These books not only lay the theoretical ground work, they are also supported by appropriate investigations of historical texts and modern medical research. To facilitate comprehension, sample formulas and herbs appropriate to each section of discussion are included. The understanding of pathomechanisms of different organs is crucial to an understanding prognosis in TCM.
A thorough glimpse into the various manifestations of spleen disease in Chinese medicine. Part 1 discusses repletion conditions of the spleen, including spleen qi depression, thought and preoccupation stagnating in the spleen, cold-damp encumbering the spleen, phlegm turbidity obstructing the spleen, food and drink damaging the spleen, and static blood accumulating in the spleen - and spleen fire (yang) exuberance - including spleen channel repletion fire and damp-heat brewing in the spleen. The second section presents vacuity conditions, including vacuity of spleen qi, spleen yang, and spleen yin.
Pathomechanisms of the Kidney describes the repletion conditions of the kidney, including kidney-channel wind-cold, wind-heat, wind-damp, cold-damp, damp-heat, repletion fire, static blood, phlegm turbidity, stones in the kidney channel, and kidney channel qi stagnation. The second section presents vacuity conditions, including vacuity of kidney yang, of kidney qi, and of kidney yin, insufficiency of kidney essence, dual vacuity of kidney yin and kidney yang, and kidney vacuity verging on desertion.
The first section discusses repletion conditions of the liver, which include: qi stagnation, phlegm obstruction, blood stasis, liver repletion cold, liver repletion heat, dampness encumbering the liver, water assailing the liver. The second section covers vacuity cold conditions, including: vacuity of liver qi, liver yang vacuity, liver blood vacuity, liver yin vacuity.
Cardiovascular Pathology, Fifth Edition provides a comprehensive treatise on the pathology of cardiovascular diseases, combining presentations of detailed pathology of cardiovascular diseases coupled with contemporary insights into etiology and pathogenesis. Twenty-two chapters cover general topics, including cardiovascular genetics, heart failure, and transplantation, and specific congenital and acquired cardiovascular diseases, therapeutic interventions, and forensic aspects. New chapters address the scope of practice and training in cardiovascular pathology, with a focus on major diagnostic approaches used in contemporary practice and research in cardiovascular pathology, and a perspective on the field of cardiovascular regenerative medicine linked to the basic pathobiology of cell-based therapy. The book provides a unique combination of details of pathological anatomy essential for pathologists involved in the evaluation of cardiovascular specimens and cardiovascular diseases, and is an excellent reference for anyone interested in the natural history and therapeutic advances in the cardiovascular field. - Includes expanded coverage of diagnostic guidelines, standards and normal values - Provides a summary of cardiac catheterization laboratory and diagnostic imaging tests to guide pathologists in clinicopathological correlation - Presents a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows in pathology, cardiology, cardiac surgery, and internal medicine - Provides comprehensive coverage, including, when appropriate, Central Concept Figure, Definition, Epidemiology, Clinical Presentation, Pathogenesis, Molecular Genetics, Light and Electron Microscopy, Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications, and a Bulleted Summary
The neuronal ceroid lipofuscinoses are an extremely rare group of inherited neurodegenerative diseases that primarily affect children. Core symptoms of these conditions typically include epilepsy, cognitive decline and visual failure. These diseases are so rare that professionals who come into contact with them need a consultative reference work that enables them to become expert, or identify who to contact for more details. Fully updated and revised, this second edition continues to be the definitive volume on this devastating group of disorders. Written by an international collection of authorities in the field, it provides invaluable advice on their diagnosis, patient care, and new treatments that are available. This new edition of the definitive reference text on the neuronal ceroid lipofuscinoses will prove useful for clinicians, family physicians, research scientists, diagnostic laboratories, families affected by the disease as well as by workers in industry planning translational research.
Knowledge of the basic mechanisms of human disease is essential for any student or professional engaged in drug research and development. Functional gene analysis (genomics), protein analysis (proteomics), and other molecular biological techniques have made it possible to understand these cellular processes, opening up exciting opportunities for no
When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as “Exosomes, naturally occurring minimal antigen presenting units” and “Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.” The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic u- ally confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease.
The ESC Textbook of Heart Failure is the latest addition to the European Society of Cardiology (ESC) publications portfolio and is fully supported by the European Heart Failure Association. The textbook brings together internationally renowned experts in the field of heart failure to present an up-to-date understanding of all aspects of this chronic condition that worsens with time. It is estimated that the worldwide population of patients suffering from heart failure is approximately 26 million. This clinically oriented work reflects contemporary European guidelines from the ESC and the European Heart Failure Association and summarizes the latest evidence from clinical trials. Made up of eighteen different sections the textbook covers the epidemiology, etiology, prevention, pathophysiology, and clinical phenotypes of heart failure. The assessment and management of chronic, acute, and advance heart failure are all discussed in detail. As well as chapters dedicated to self-care and patient education, the multidisciplinary approach to heart failure management, and clinical trial design and interpretation. The future direction of the field is discussed throughout with separate chapters on digital health, big data, and telemedicine/remote monitoring in heart failure also included. A must read for cardiovascular healthcare specialists in Europe and across the world it should also appeal to those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, and specialist nurses too.
