Progress in Parkinson Research

Progress in Parkinson Research

Author: Franz Hefti

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 225

ISBN-13: 1461307597

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In the past five years significant progress has been made in our basic and clinical under standing of Parkinson's disease. The discovery that MPTP, a relatively simple molecule, is able to induce parkinsonism in otherwise healthy adult humans, and the recent interest in the possibility of "transplantation" procedures as a therapeutic modality in the treatment of Parkin son's disease have generated enormous interest in research related to Parkinson's disease. In this setting, the National Parkinson Foundation decided to organize a research meeting to bring together scientists actively engaged in research relevant to the study of Parkinson's disease, to accelerate its progress and to promote an exchange of ideas. This meeting took place in Janu ary 1988 at Key Biscayne, Florida. It was decided to publish the proceedings ofthis meeting to allow rapid documentation of the participants current findings and views regarding this rapidly of this volume follows the organization of the meeting and begins evolving field. The structure with a clinical and neuropathological review of current knowledge regarding Parkinson's dis ease. Since dopaminergic neurons playa major role in the pathophysiology of the disease, many of the contributions relate to some aspects of dopaminergic function including localiza tion, regulation, and pharmacology of dopamine receptors. A special effort has been made to provide a summary of the present knowledge of the cellular biology of the dopaminergic neurons.


Progress in Parkinson's Disease Research--2

Progress in Parkinson's Disease Research--2

Author: Franz Hefti

Publisher: Wiley-Blackwell

Published: 1992-01-01

Total Pages: 503

ISBN-13: 9780879935306

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There has been a surge of progress made in recent years in Parkinson′s research. The cloning of receptors for dopamine has been realized, and significant advances have been made in understanding the molecular nature of the interaction between dopamine and mediation of its actions in the brain. In addition, the mechanisms of action of MPTP, a toxin producing parkinsonism in humans and animals, has been further elucidated and is now largely understood. With many contributions on the loss of dopaminergic neurons, the hallmark of Parkinson′s disease, Progress in Parkinson′s Disease Research – 2 reports on current progress with the hope of accelerating future research efforts in the field. This book brings together top scientists actively engaged in research relevant to Parkinson′s disease.


Etiology of Parkinson's Disease

Etiology of Parkinson's Disease

Author: Jonas H. Ellenberg

Publisher: CRC Press

Published: 1995-03-01

Total Pages: 600

ISBN-13: 9780824788230

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This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.


Recent Advances in Parkinsons Disease

Recent Advances in Parkinsons Disease

Author:

Publisher: Elsevier

Published: 2010-09-29

Total Pages: 333

ISBN-13: 0444536140

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This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research All chapters include comprehensive background information and are written in a clear form that is accessible also to the non-specialist


Rating Scales in Parkinson's Disease

Rating Scales in Parkinson's Disease

Author: Cristina Sampaio

Publisher: Oxford University Press

Published: 2012-06-28

Total Pages: 342

ISBN-13: 0199783101

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For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another.


Mapping the Progress of Alzheimer’s and Parkinson’s Disease

Mapping the Progress of Alzheimer’s and Parkinson’s Disease

Author: Yoshikuni Mizuno

Publisher: Springer Science & Business Media

Published: 2002-03-31

Total Pages: 596

ISBN-13: 9780306467639

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1h The 5 International Conference on the Progress in Alzheimer's Disease and Parkinson's 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a joint Congress with the 9 International Catecholamine Symposium. A total of 1258 clinicians and researchers participated in this joint congress 1h from 38 countries in the world. This book represents the proceedings of the 5 Conference on Alzheimer's and Parkinson's disease. The International Conference on the Progress in Alzheimer's and Parkinson's disease was first launched by Professor Abraham Fisher of Israel and Professor Israel Hanin of USA. The first conference was held in Eilat, Israel in 1985. The second conference was organized in Kyoto, Japan in 1989; the third one in Chicago, USA, in 1993, and the fourth one in Eilat, Israel in 1997. The International Catecholamine Symposium (ICS) is an international meeting devoted to the development of basic as well as clinical research on catecholamines. The first Catecholamine Symposium was held in Bethesda, USA in 1958. Since then this symposium has occurred every 5 years. Professor Toshiharu Nagatsu was appointed as 1h the president of the 9 International Catecholamine Symposium, which was to be held in 200 I also in Japan. Therefore, we decided to organize a joint congress of the two meetings, because there is much overlap in research between Alzheimer's disease, Parkinson's disease, and catecholamines. We thank Professor Nagatsu very much for agreeing to organizing this joint congress.