Helicobacter pylori in Human Diseases
Helicobacter pylori in Human Diseases

Author: Shigeru Kamiya

Publisher: Springer Nature

Published: 2019-10-22

Total Pages: 297

ISBN-13: 303021916X

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This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.

Proton Pump Inhibitors: A Balanced View
Proton Pump Inhibitors: A Balanced View

Author: T. Chiba

Publisher: Karger Medical and Scientific Publishers

Published: 2013-09-23

Total Pages: 130

ISBN-13: 3318024155

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The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of enormous value in gastroenterology. The authors provide an update on a variety of subjects, starting with an introduction to the discovery and development of PPIs. This is followed by chapters on pharmacokinetics, pharmacodynamics and pharmacogenetics, gastroesophageal reflux disease, gastroprotection, Helicobacter pylori eradication treatment, peptic ulcer disease, functional dyspepsia, acid suppression in exocrine pancreatic insufficiency, and gastrointestinal and systemic side effects. Readers who are interested in a current overview of PPIs and their various applications will find this book of great value.

Helicobacter pylori
Helicobacter pylori

Author: Nayoung Kim

Publisher: Springer

Published: 2016-06-16

Total Pages: 532

ISBN-13: 9812877061

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This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.

Helicobacter Pylori
Helicobacter Pylori

Author: Bruna Maria Roesler

Publisher: BoD – Books on Demand

Published: 2019-09-18

Total Pages: 136

ISBN-13: 183881146X

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Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.

Helicobacter Pylori in the 21st Century
Helicobacter Pylori in the 21st Century

Author: Philip Sutton

Publisher: CABI

Published: 2010

Total Pages: 316

ISBN-13: 1845935942

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This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Pharmacology of Peptic Ulcer Disease
Pharmacology of Peptic Ulcer Disease

Author: Martin J. Collen

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 478

ISBN-13: 3642758584

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In this book the pathophysiology, diagnosis, and therapy of most aspects of peptic ulcer disease are examined in detail. Covered are the pharmacology of the parietal cell and the latest hypotheses for the development of acid-peptic disease including epidermal growth factor, gastrin and other peptide hormones, fatty acids and prostaglandins, helicobacter pylori, and gastric acid hypersecretion including Zollinger-Ellison syndrome. The book also deals with the newer antisecretory medication such as omeprazole with a review of H2-receptor antagonists. Rounding off the subject are chapters on gastroesophageal reflux disease, upper GI endoscopy, and videoendoscopy including digital imaging. This volume addresses a wide range of physicians who are interested in all aspects of acid-peptic disease. What distinguishes this volume from others is the timely update on a number of important issues pertaining to acid-peptic disease. Not only does it review a number of topics that are of great interest at the present time, but it introduces a vast amount of new unpublished data.

Helicobacter pylori
Helicobacter pylori

Author: R.H. Hunt

Publisher: Springer

Published: 2012-10-28

Total Pages: 612

ISBN-13: 9789401046206

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Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture. The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy. The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.

Clinical Periodontology and Implant Dentistry, 2 Volume Set
Clinical Periodontology and Implant Dentistry, 2 Volume Set

Author: Niklaus P. Lang

Publisher: John Wiley & Sons

Published: 2015-04-07

Total Pages: 1480

ISBN-13: 1118940474

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Now in its sixth edition, Clinical Periodontology and Implant Dentistry is the must-have resource for practitioners specialising in periodontal care and implant dentistry. The chapters have been extensively revised with 40% of the content new to this edition. Maintaining the widely praised two-volume format introduced in the previous edition, the editorial team has once again brought together the world’s top international specialists to share their expertise on all aspects of periodontology, periodontal health and the use of implants in the rehabilitation of the periodontally compromised patient. Seamlessly integrating foundational science, practical clinical protocols, and recent advances in the field, Clinical Periodontology and Implant Dentistry, Sixth Edition enhances its stellar reputation as the cornerstone reference work on periodontology.

Helicobacter Pylori
Helicobacter Pylori

Author: Sinead M Smith

Publisher: Humana

Published: 2021-03-26

Total Pages: 234

ISBN-13: 9781071613016

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This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.