Oxford Textbook of Cancer Biology
Oxford Textbook of Cancer Biology

Author: Francesco Pezzella

Publisher: Oxford University Press

Published: 2019-05-02

Total Pages: 505

ISBN-13: 0198779453

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The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Hollywood Highbrow
Hollywood Highbrow

Author: Shyon Baumann

Publisher: Princeton University Press

Published: 2018-06-05

Total Pages: 242

ISBN-13: 0691187282

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Today's moviegoers and critics generally consider some Hollywood products--even some blockbusters--to be legitimate works of art. But during the first half century of motion pictures very few Americans would have thought to call an American movie "art." Up through the 1950s, American movies were regarded as a form of popular, even lower-class, entertainment. By the 1960s and 1970s, however, viewers were regularly judging Hollywood films by artistic criteria previously applied only to high art forms. In Hollywood Highbrow, Shyon Baumann for the first time tells how social and cultural forces radically changed the public's perceptions of American movies just as those forces were radically changing the movies themselves. The development in the United States of an appreciation of film as an art was, Baumann shows, the product of large changes in Hollywood and American society as a whole. With the postwar rise of television, American movie audiences shrank dramatically and Hollywood responded by appealing to richer and more educated viewers. Around the same time, European ideas about the director as artist, an easing of censorship, and the development of art-house cinemas, film festivals, and the academic field of film studies encouraged the idea that some American movies--and not just European ones--deserved to be considered art.

Plasticity in the Adult Brain: From Genes to Neurotherapy
Plasticity in the Adult Brain: From Genes to Neurotherapy

Author: M.A. Hofman

Publisher: Elsevier

Published: 2002-10-23

Total Pages: 497

ISBN-13: 008049773X

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In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.

Understanding Alzheimer's
Understanding Alzheimer's

Author: Prof Ralph Martins

Publisher: Macmillan Publishers Aus.

Published: 2013-09-01

Total Pages: 266

ISBN-13: 1743289510

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Understanding Alzheimer's is a practical guide for the hundreds of thousands of Australians dealing with this extremely challenging condition. Each week, 1500 Australians are diagnosed with Alzheimer's or a dementia-related illness. This timely book answers many of the common questions asked by carers, patients and the public, including: · How is Alzheimer's diagnosed? · Is it possible to prevent and/or slow down the disease? · What are the risk factors for contracting Alzheimer's? · What are the best current treatments, and what is the research telling us about new treatments? · How can diet, physical activity and mental exercise be used to help manage the disease? · What are the emotional and legal issues around caring for someone with Alzheimer's? Drawing on some of Australia's top experts in the field, and containing numerous personal stories and a section on where to get help, this guide offers the best and latest medical information as well as compassionate and reassuring advice for those whose lives are affected by Alzheimer's.