Reactive Intermediates in Organic Chemistry
Reactive Intermediates in Organic Chemistry

Author: Maya Shankar Singh

Publisher: John Wiley & Sons

Published: 2014-01-22

Total Pages: 362

ISBN-13: 3527678271

DOWNLOAD EBOOK

Most reactions in organic chemistry do not proceed in a single step but rather take several steps to yield the desired product. In the course of these multi-step reaction sequences, short-lived intermediates can be generated that quickly convert into other intermediates, reactants, products or side products. As these intermediates are highly reactive, they cannot usually be isolated, but their existence and structure can be proved by theoretical and experimental methods. Using the information obtained, researchers can better understand the underlying reaction mechanism of a certain organic transformation and thus develop novel strategies for efficient organic synthesis. The chapters are clearly structured and are arranged according to the type of intermediate, providing information on the formation, characterization, stereochemistry, stability, and reactivity of the intermediates. Additionally, representative examples and a problem section with different levels of difficulty are included for self-testing the newly acquired knowledge. By providing a deeper understanding of the underlying concepts, this is a musthave reference for PhD and Master Students in organic chemistry, as well as a valuable source of information for chemists in academia and industry working in the field. It is also ideal as primary or supplementary reading for courses on organic chemistry, physical organic chemistry or analytical chemistry.

Reviews of Reactive Intermediate Chemistry
Reviews of Reactive Intermediate Chemistry

Author: Matthew S. Platz

Publisher: John Wiley & Sons

Published: 2007-04-20

Total Pages: 492

ISBN-13: 0470120819

DOWNLOAD EBOOK

The chemistry of reactive intermediates is central to a modern mechanistic and quantitative understanding of organic chemistry. Moreover, it underlies a significant portion of modern synthetic chemistry and is integral to a molecular view of biological chemistry. Reviews in Reactive Intermediate Chemistry presents an up-to-date, authoritative guide to this fundamental topic. Although it follows Reactive Intermediate Chemistry by the same authors, it serves as a free-standing resource for the entire chemical and biochemical community. The book includes: Relevant, practical applications Coverage of such topics as mass spectrometry methods, reactive intermediates in interstellar medium, quantum mechanical tunnelling, solvent effects, reactive intermediates in biochemical processes, and excited state surfaces Discussions of emerging areas, particularly those involving dynamics and theories Concluding sections identifying key directions for future research are provided at the end of each chapter

Organic reactive intermediates
Organic reactive intermediates

Author: Samuel McManus

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 552

ISBN-13: 0323146279

DOWNLOAD EBOOK

Organic Chemistry: A Series of Monographs, Volume 26: Organic Reactive Intermediates focuses on the study of reactive intermediates. This book discusses the methods of formation and investigation, factors affecting the stability, and reactions of the intermediate. Other topics include the formation and reaction of free radicals; kinetic aspects of free-radical chain reactions; electronic states and structures of carbenes; and formation of transient carbenes and carbenoids in solution. The intermediacy of nitrenes in reactions; electronic structure and spectra; methods of investigating carbonium ions; and reactions of carbonium ions are also elaborated. This publication likewise covers the preparation of carbanions; factors affecting the stability of carbanions; reactions involving radical ions; and methods of investigating arynes. This volume serves as a textbook for the first graduate-level course, as well as a reference for industrial chemists interested in organic reaction mechanisms.

Reactive Molecules
Reactive Molecules

Author: Curt Wentrup

Publisher: Wiley-Interscience

Published: 1984-03-21

Total Pages: 360

ISBN-13:

DOWNLOAD EBOOK

Designed for advanced undergraduate and graduate organic chemistry students, here's an up-to-date, in-depth textbook on the chemistry of neutral reactive intermediates--free radicals, diradicals, carbenes, nitrenes, strained rings, and antiaromatics. Includes numerous tables of physical data and extensive references to present day research in the field.

Reactive Intermediate Chemistry
Reactive Intermediate Chemistry

Author: Robert A. Moss

Publisher: John Wiley & Sons

Published: 2004-01-07

Total Pages: 1088

ISBN-13: 9780471233244

DOWNLOAD EBOOK

Reactive Intermediate Chemistry presents a detailed and timely examination of key intermediates central to the mechanisms of numerous organic chemical transformations. Spectroscopy, kinetics, and computational studies are integrated in chapters dealing with the chemistry of carbocations, carbanions, radicals, radical ions, carbenes, nitrenes, arynes, nitrenium ions, diradicals, etc. Nanosecond, picosecond, and femtosecond kinetic realms are explored, and applications of current dynamics and electronic structure calculations are examined. Reactive Intermediate Chemistry provides a deeper understanding of contemporary physical organic chemistry, and will assist chemists in the design of new reactions for the efficient synthesis of pharmaceuticals, fine chemicals, and agricultural products. Among its features, this authoritative volume is: Edited and authored by world-renowned leaders in physical organic chemistry. Ideal for use as a primary or supplemental graduate textbook for courses in mechanistic organic chemistry or physical chemistry. Enhanced by supplemental reading lists and summary overviews in each chapter.

Intermediates for Organic Synthesis
Intermediates for Organic Synthesis

Author: V. K. Ahluwalia

Publisher: I. K. International Pvt Ltd

Published: 2013-12-30

Total Pages: 372

ISBN-13: 8188237337

DOWNLOAD EBOOK

The intermediates described in this book include different types of phenols, aldehydes, carboxylic acids and ketones (acetophenones, w-substituted acetophenones, propiophenones, butyrophenones, benzophenones, phenyl ketones and some miscellaneous ketones). The preparation of heterocyclic compounds (O-containing, S-containing, N-containing, N & S-containing) is also described. The synthesis of certain miscellaneous compounds of the type benzyl cyanides, b-ketoesters, chalcones, naphthaquinones, benzoquinones, stilbene and certain catalysts and reagents required for organic synthesis are also described. The present book aims to make available detailed procedures for the synthesis of various intermediates, which are generally required by organic chemists working in various universities, industries and by the research scholars at different levels. No single publication is available describing the intermediates required for organic synthesis. Attempt has been made to describe the best possible procedures with ample experimental details keeping in mind the maximum yield. The authors and their associates have verified all the procedures described.

Organometallic Mechanisms and Catalysis
Organometallic Mechanisms and Catalysis

Author: Jay Kochi

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 642

ISBN-13: 0323144101

DOWNLOAD EBOOK

Organometallic Mechanisms and Catalysis: The Role of Reactive Intermediates in Organic Processes covers the mechanistic delineation of organometallic chemistry and catalysis. This book is organized into three parts encompassing 18 chapters. The first part describes first the oxidation-reduction process of organometals, followed by discussions on the catalytic reactions of peroxides, metal-catalyzed addition to olefins, and reduction of organic halides. This part also explores other reactions involving transition metal carbonyls and metal-catalyzed reactions of aromatic diazonium salts. The second part deals with some chemical aspects of organometals, such as their stability, thermochemistry, decomposition, hemolytic pathways, and the formation of carbon-carbon bonds. The third part examines the charge transfer processes and interactions of organometals with electron acceptors. This part further looks into the cleavage and insertion reactions of organometals with electrophiles, as well as the electrophilic and electron transfer mechanisms of organometals. Organic and inorganic chemists, teachers, and students will greatly benefit from this book.

The Investigation of Organic Reactions and Their Mechanisms
The Investigation of Organic Reactions and Their Mechanisms

Author: Howard Maskill

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 392

ISBN-13: 0470994169

DOWNLOAD EBOOK

A range of alternative mechanisms can usually be postulated for most organic chemical reactions, and identification of the most likely requires detailed investigation. Investigation of Organic Reactions and their Mechanisms will serve as a guide for the trained chemist who needs to characterise an organic chemical reaction and investigate its mechanism, but who is not an expert in physical organic chemistry. Such an investigation will lead to an understanding of which bonds are broken, which are made, and the order in which these processes happen. This information and knowledge of the associated kinetic and thermodynamic parameters are central to the development of safe, efficient, and profitable industrial chemical processes, and to extending the synthetic utility of new chemical reactions in chemical and pharmaceutical manufacturing, and academic environments. Written as a coherent account of the principal methods currently used in mechanistic investigations, at a level accessible to academic researchers and graduate chemists in industry, the book is highly practical in approach. The contributing authors, an international group of expert practitioners of the techniques covered, illustrate their contributions by examples from their own research and from the relevant wider chemical literature. The book covers basic aspects such as product analysis, kinetics, catalysis, and investigation of reactive intermediates. It also includes material on significant recent developments, e.g. computational chemistry, calorimetry, and electrochemistry, in addition to topics of high current industrial relevance, e.g. reactions in multiphase systems, and synthetically useful reactions involving free radicals and catalysis by organometallic compounds.