Discusses issues involved with organ procurement and preservation for transplantation including donor procurement criteria, perfusion and storage techniques, cryopreservation, ischemia/reperfusion injury and metabolic regulation. This book covers the kidney, liver, pancreas, small bowel, heart and lung, and informs the reader about preservation and procurement developments in the field of transplantation.
This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
It is like a fairy story! Or at least a beautiful epic, a truly significant page in the history of medicine, a staggering scene in which several actors come into play, both fundamentalists and clinical practitioners, eager to place all these new developments at the disposal of those suffering from ill health. Everyone is passionate about their work, be it providing new knowledge or perfecting new therapeutic methods. Man has always been fascinated by the possibility of replacing a damaged organ with a healthy one. Several attempts have been made over the centuries, and some miracles have been reported, such as those of Saint Damien and Saint Come as illustrated by Fra Angelico. The modern saga, however, started more modestly on the mouse. It is on the mouse that the first tissue group was discovered; yet the study of human tissue groups could only be carried out on a human. One human must be subjected to the thousands of tests that have enabled us to unravel the extraordinary complexity of the HLA system.
The first basic overview of all aspects of transplantation with a clarity not to be found in more inaccessible textbooks. This brand new title provides a succinct overview of both the scientific and clinical principles of organ transplantation and the types of organ transplant, featuring highly-illustrated information covering core topics in transplantation including: Organ donors Organ preservation Assessment of transplant recipients Indications for transplantation Immunology of transplantation Immunosuppression and its complications Overviews of thoracic and abdominal organ transplantation, including the kidneys, liver, heart and lungs Transplantation at a Glance is the ideal introduction for medical students, junior doctors, surgical trainees, immunology students, pharmacists, and nurses on transplant wards.
Organ Preservation Surgery for Laryngeal Cancer is the first book/CD-R OM package to focus solely on the surgical techniques that preserve th e functions of speech and swallowing without a permanent tracheostomy.
The book encompasses Dr Baranski’s 20 year experience in the field of abdominal organ donation. It is a step-by-step guide with photographs and drawings with clear explanations highlighting pitfalls. The book quickly and easily guides the reader through the difficult steps during organ procurement. It is mainly illustration-based, without much text, and covers surgical technical mistakes and organ damage.
The first edition of this book, Basic Concepts in Organ Procurement, Perfusion and Preservation for Transplantation, was published 27 years ago, in 1982 when organ procurement and preservation began to advance in the study of the best ways to preserve organs for transplantation. The second edition, Organ Procurement and Preservation for Transplantation, 2nd Edition, followed 15 years later, in 1997, with the goal of finding common denominators in the best preservation techniques for transplantation. In this current third edition, 11 years after the second edition, similar goals are still pursued of defining the best preservation methods, but there is now more evidence, including results, and new advances have reached publication and are being incorporated into ischemia and reperfusion techniques and organ preservation studies. Many preservation solutions have been introduced, important preservation solution components have been better defined, and improved perfusion methods are being considered, especially for the increasing number of organ donors with non-beating hearts who are being sought for transplantation. This edition (2009) engaged experts in the field of organ preservation to review, update, and rewrite each of the chapters. Crafted in collaboration with Luis H. Toledo-Pereyra, the text is eminently informative and easily understandable. Each solid organ that can be transplanted has an entire chapter devoted to the particular methods of its preservation. One chapter apiece, in other words, features insights on the preservation of the kidney, the liver, the pancreas, the small bowel, the heart, and the heart-lung. The title of the present book has been shortened to better represent its content. Thus, Organ Preservation for Transplantation, 3rd Edition, demonstrates a more accurate depiction of its current status. Nevertheless, the goal of this book remains exactly the same as in the first edition, that is “to analyze the most important aspects of organ procurement, perfusion and preservation for transplantation”.
Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation. Covers all aspects of organ preservation, repair and regeneration Addresses the repair of organs that experience an Ischemia/Reperfusion (I/R) injury, those that are intended for transplantation, and specific issues related to each organ Presented by editors and authors who are physicians, surgeons and researchers in the field of organ transplantation and regenerative medicine
Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.
Abdominal organ transplantation is a complex, multi-step process that requires flawless surgery from start to finish. Training in organ retrieval and bench surgery, however, has varied from country to country and even center to center, and trainees too often must rely on hands-on experience without the benefit of extensive practical or theoretical training. With the number of transplant programs on the rise and the demand for donor organs increasing steadily as outcomes continue to improve, there is a greater need than ever before for a practical and comprehensive reference that transplantation professionals can turn to for clear and comprehensive guidance. Abdominal Organ Retrieval and Transplantation Bench Surgery fills that need. This important new book covers all aspects of retrieval and bench surgery of the abdominal organs. Coverage includes organ retrieval logistics and organ preservation; retrieval and bench surgery of the kidney, liver, pancreas and intestine; in situ and ex situ liver splitting; multi-organ retrieval; paediatric age-specific aspects of retrieval and bench surgery; and more. Key features include: Practice learning points for each procedure Detailed color illustrations of standard techniques Thorough guidance on dealing with anatomical variations Abdominal Organ Retrieval and Transplantation Bench Surgery is the ideal guide for surgeons and donor retrieval teams alike. With its step-wise approach and practical orientation, it is a reference transplant professionals can trust to help them understand and excel at all aspects of abdominal organ retrieval, from managing potential donors and properly retrieving organs to minimizing the likelihood of common pitfalls while mastering the latest surgical techniques.
