Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Author: Tahira Farooqui

Publisher: Academic Press

Published: 2017-10-24

Total Pages: 485

ISBN-13: 0128119608

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Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline. - Comprehensively provides an overview of the effects of the Mediterranean diet on the brain and its beneficial effects in neurodegenerative diseases - Discusses the relationship among Type 2 Diabetes, Metabolic Syndrome and Alzheimer's Disease, and the effect of the Mediterranean diet on normal aging, longevity, and other neurodegenerative diseases - Focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative disease


Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Author: Debasis Bagchi

Publisher: Academic Press

Published: 2012-01-31

Total Pages: 553

ISBN-13: 0123850835

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Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options


Nutrition and Prevention of Alzheimer's Disease

Nutrition and Prevention of Alzheimer's Disease

Author: Claudia Perez-Cruz

Publisher: Frontiers Media SA

Published: 2015-12-18

Total Pages: 78

ISBN-13: 2889197190

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Altered metabolism is known to be associated with a higher incidence of Alzheimer´s disease (AD). Diabetes type 2, obesity, and metabolic syndrome are considered risk factors for the development of dementias, including AD. These metabolic diseases may have a genetic predisposition, but most of them are caused by environmental factors and life-style. Most research has focused on the effect of a high-fat diet (HFD) and sweetened beverages that induce obesity. Importantly, a HFD can also trigger oxidative stress, neuro-inflammation and cognitive decline. Less is known, however, about beneficial effects of diet on cognition, such as slowing the progression or preventing AD by ingesting whole fruits, vegetables, fish and oil. It is important to highlight the difference between vitamin/mineral supplements and whole food, as it appears that the former are clinically ineffective, while multiple ingredients in the latter act synergistically to improve cognition. As AD is a disease of slow progression, therapies should start several decades before clinical symptoms can be observed; one strategy can be the ingestion of healthy food in those subjects with one or more risk factors (genetic, environmental, life-style) already in their 40s, just when some brain metabolic disturbances start to develop. This dietary therapy can overcome the increased reactive oxygen species, protein deposition and synaptic failure, characteristic of AD. This research topic will cover a range of research articles, case studies, opinion and mini-reviews, all focused on describing the damaging effects of an industrial diet on cognition as well as on highlighting the beneficial effects of a healthy diet to prevent AD. We believe that we still have time to fight against the negative impact of our industrialized cultures, and adopt better eating habits, increase exercise and slow down our life style to prevent increasing dementia in the aging population. Also, all these topics has been a product of intensives investigations, with a great life hope, and we hope you all enjoy reading this e-book.


Nutrition and Disease

Nutrition and Disease

Author: Kenneth Lundstrom

Publisher: Cambridge Scholars Publishing

Published: 2020-02-24

Total Pages: 180

ISBN-13: 1527547531

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Nutrition is an essential part of life. It affects our health and can be applied in the prevention and treatment of disease. Substantial interventions in dietary intake and lifestyle changes have been demonstrated to cause significant decrease in disease risk in in the general population and also in patients suffering from various diseases. Traditional plant-based diets and medicines have received much attention as an alternative to modern science-based drugs, while recent technology development in bioinformatics, genomics, and proteomics has provided a better understanding of plant-based drugs, improved quality assurance and allowed the acceleration of clinical trials to bridge the gap with Western medicine. Moreover, research in nutrigenomics and epigenomics has further enhanced the knowledge of the association between nutrition and disease. The book deals with the concerns of the future well-being of our planet, the health of the global human population related to the worldwide obesity epidemic, the issues related to sustainable food production, and the need for a switch to a healthier, more plant-based diet.


Oxidative Stress and Neurodegenerative Disorders

Oxidative Stress and Neurodegenerative Disorders

Author: G. Ali Qureshi

Publisher: Elsevier

Published: 2007-03-22

Total Pages: 795

ISBN-13: 0080489494

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Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders.* Contains the latest information on the subject of neurodegenerative disorders* Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems


Neurodegenerative Disease and Micronutrients

Neurodegenerative Disease and Micronutrients

Author: Kedar N. Prasad

Publisher: CRC Press

Published: 2016-10

Total Pages: 350

ISBN-13: 9781138034143

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The book proposes that a preparation of antioxidants and micronutrients, in combination with standard therapy, may reduce progression and improve management better than standard therapy alone for Alzheimer s, Parkinson s, and Huntington s disease, as well as PTSD, traumatic brain injury, concussions, and cerebral vascular insufficiency. The book presents the latest research on the effects of micronutrients and recommends formulations for use in combination with standard therapies for these neurodegenerative diseases and conditions. "


Functional Foods, Nutraceuticals, and Degenerative Disease Prevention

Functional Foods, Nutraceuticals, and Degenerative Disease Prevention

Author: Gopinadhan Paliyath

Publisher: John Wiley & Sons

Published: 2011-08-15

Total Pages: 435

ISBN-13: 0470960825

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Functional Foods, Nutraceuticals and Degenerative Disease Prevention is a compilation of different segments of functional foods and nutraceuticals focusing on their mechanism of action in the human body leading to disease prevention. Numerous chapters deal with different functional foods in terms of their efficacy, highlighting the mechanism of action of their ingredients. The book focuses on the biochemistry and molecular biology of the disease prevention process rather than simply compiling the benefits of functional foods and nutraceuticals. Aimed primarily at an audience comprised of researchers, industry professionals, food scientists, medical professionals and graduate level students, Functional Foods, Nutraceuticals and Degenerative Disease Prevention offers a mechanism-based interpretation for the effect of nutraceuticals within the human body. Ultimately, the discussion of the biological effects of a variety of functional foods will provide a wholesome approach to the maintenance of health through judicious choice of functional foods.


Diet and Cognitive Decline

Diet and Cognitive Decline

Author: Francesco Panza

Publisher: Nova Publishers

Published: 2004

Total Pages: 188

ISBN-13: 9781594541216

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The progressive ageing of the general population and the consequent increase of the number of old people has made the typical medical problems of aged people more frequently observed, and particularly the problems related to the ageing brain. This new book is an updated overview of relevant aspects of cognitive decline associated with ageing. Within the wide landscape of brain ageing the authors reconsider the role of the main predisposing factors and risk factors on the development of various form of mental decline, from mild cognitive impairment to dementia. The strength of this book is the large, updated overview of the most recent data of scientific literature regarding the role of genetic, metabolic and environmental factors on the predisposition and onset of cognitive decline. Particular attention is paid to the dietary micro- and macronutrients and to their possible role in the pathogenesis of the various form of dementigen disorders.


Nutraceuticals in Brain Health and Beyond

Nutraceuticals in Brain Health and Beyond

Author: Dilip Ghosh

Publisher: Academic Press

Published: 2020-11-12

Total Pages: 478

ISBN-13: 0128206101

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Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer's, Parkinson's, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses "herb-nutra psychiatry" which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health.Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health. - Addresses nutritional psychiatry and cognitive health at all stages of the lifespan - Contains extensive coverage of vitamins, minerals, botanicals, and other nutrients - Offers novel insight into cognitive dysfunctions including depression and other neurodegenerative disorders - Explores the role of genomics and epigenetics, including discussion of the gut–brain axis