Polyphenols and carotenoids are abundant in fruits, vegetables, herbs and spices, and beverages, such as tea, cocoa and wine providing health-related benefits and antioxidant properties. Focusing on non-extractable polyphenols and carotenoids that are present in the diet, this book will improve our knowledge of dietary intakes and physiological properties ensuring a better understanding of their potential health effects. With global appeal, this will be the first book dedicated to raising the profile of this important area. Summarising the current knowledge in the field, the book will direct further research for food chemists, scientists and nutritionists looking for new perspectives.
Focusing on non-extractable polyphenols (NEPP) that are present in the diet, this book will improve our knowledge of dietary intakes and physiological properties of NEPP ensuring a better understanding of their potential health effects.
Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.
The Special Issue “Extractable and Non-Extractable Antioxidants” gives an updated view on antioxidants—both in their extractable and non-extractable form—in the different food groups, their products thereof, and food preparations as well as byproducts and biomass waste. The potential beneficial properties of these compounds and nutraceutical formulations are described in the various studies covered in this Special Issue.
Plant polyphenols are specialized metabolites that constitute one of the most common and widespread groups of natural products. They are essential plant components for adaptation to the environment and possess a large and diverse range of biological functions that provide many benefits to both plants and humans. Polyphenols, from their structurally simplest forms to their oligo/polymeric versions (i.e. tannins and lignins), are phytoestrogens, plant pigments, antioxidants, and structural components of the plant cell wall. The interactions between tannins and proteins are involved in plant defense against predation, cause astringency in foods and beverages, and affect the nutritional and health properties of human and animal food plants. This eighth volume of the highly regarded Recent Advances in Polyphenol Research series is edited by Juha-Pekka Salminen, Kristiina Wähälä, Victor de Freitas, and Stéphane Quideau, and brings together chapters written by some of the leading experts working in the polyphenol sciences today. Topics covered include: Structure, reactivity and synthesis Bioactivity and bioavailability Metabolomics, targeted analysis and big data Quality control & standardization Biogenesis and functions in plants and ecosystems Biomaterials & applied sciences Distilling the most recent and illuminating data available, this new volume is an invaluable resource for chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists.
Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
Food byproducts derived from industrial processing is a serious worldwide problem because it generates environmental pollution and results in significant food and economic losses from food waste. This new volume shows how food byproducts can be value-added renewable sources with the application of novel biotechnologies that avoid hazardous chemicals. The volume discusses the importance of valorizing food wastes and illustrates their value-added properties for industry. It explains the significant progress in bioresources processing for compound extraction and production as well as the increasing interest of food ingredients development, in which health care, environment, and economics play an essential part in biotechnological research. It considers the waste byproducts of various crops, such as tomato, melon, maize, berries, soybean, coffee, and their uses in the generation of health-benefiting bioactive compounds. The volume goes on to explore the various biotechnological strategies to extract, produce, and recover bioactive compounds along with the cost-effectiveness of these methods. Key features: Describes technological aspects in consolidated processing and bioprocessing of food by-products Discusses technological aspects in biotechnology for food byproducts treatment and the richness of their biomolecules Looks at the nutraceutical and health benefit aspects of such biomolecules from food waste byproducts Provides attractive and sustainable methodologies for bioproduct extraction and recovery for industrial application This volume, Food Byproducts Management and Their Utilization, presents strategies that are of interest in food engineering, green chemistry, biotechnology, and some other areas, while paying special attention to biorefinery approaches and new challenges that industries are dealing with in the era of sustainable development. It aims to encourage not only researchers but also governmental and enterprise sectors to recognize the value and applications of food byproducts and waste.
This Special Issue is dedicated to gathering the latest advances in the food sources, chemistry, analysis, composition, formulation, use, experience in clinical use, mechanisms of action, available data of nutraceuticals, and natural sources that represent a new frontier for therapy and provide valuable tools to reduce the costs for both environment and healthcare systems.
Nutraceuticals are a challenge for the future of prevention and therapy in healthcare. The possibility to prevent and/or support pharmacological therapy, which is nowadays mainly based on pharmaceuticals, can be a powerful tool to face pathological, chronic, long-term diseases in subjects who do not qualify for a pharmacological therapy. Nutraceuticals are obtained from vegetal or animal origin foods, and prospective research on these products will clarify their role, safety and efficacy by substantiating their role with clinical data. An effort to clarify their mechanism of action will open a door to the next generation of therapeutic agents that do not propose themselves as an alternative to drugs, but, instead, can be helpful to complement a pharmacological therapy, and to prevent the onset of chronical diseases. The market as well as the interest of people in naturally-derived remedies and less synthetic pharmaceuticals is growing, and the attention of the collective public imagination is nowadays more strongly focused on these food-derived products. This Special Issue is dedicated to the role of and perspectives on nutraceuticals in human health, examined from different angles ranging from analytical aspects to clinical trials, and from efficacy studies to beneficial effects on health conditions.
Natural products have always captivated the imagination of scientists, researchers, and enthusiasts alike. They are the Earth's rich reservoir of chemical diversity, offering a vast array of compounds with fascinating structures and often remarkable biological activities. From the earliest discoveries of quinine and morphine to the modern isolation of complex molecules from the depths of the ocean, the field of natural product chemistry has been a journey of continuous exploration and revelation. This book, "Chemistry of Natural Products," is an exploration of that journey. It aims to provide a comprehensive overview of the chemistry, structure, and significance of natural products derived from a wide variety of sources, including plants, microorganisms, marine organisms, and more. While natural products have been used for millennia for their medicinal, nutritional, and even mystical properties, their relevance extends far beyond ancient traditions. In the following pages, we delve into the fascinating world of natural products, uncovering the intricacies of their chemical structures, the mechanisms behind their synthesis in nature, and their roles in ecological systems. The study of these compounds has provided insights into the evolution of life and has yielded invaluable leads for the development of pharmaceuticals, agrochemicals, and other useful products. We explore the isolation, characterization, and biosynthesis of natural products and delve into their diverse applications in the realms of medicine, agriculture, and industry.Throughout this book, we emphasize the interdisciplinary nature of natural product chemistry, as it bridges the fields of chemistry, biology, pharmacology, and ecology. It is our hope that this text will be a valuable resource for students, researchers, and anyone with an interest in the world of natural products. We have strived to present the information in a manner that is accessible, informative, and engaging, allowing readers to appreciate the wonders of these compounds and their significance in our lives. It is essential to acknowledge the countless researchers, scientists, and scholars who have dedicated their lives to the exploration of natural products, as their contributions have been instrumental in shaping our understanding of these compounds. We also extend our gratitude to the institutions, organizations, and funding agencies that have supported research in this field. As you embark on this journey through the "Chemistry of Natural Products," we invite you to delve into the intricacies and marvels of nature's chemical creations, each with its unique story waiting to be told.
