Nicotinic Receptors

Nicotinic Receptors

Author: Robin A.J. Lester

Publisher: Springer

Published: 2014-11-11

Total Pages: 468

ISBN-13: 1493911678

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A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.


Neuronal Nicotinic Receptors

Neuronal Nicotinic Receptors

Author: F. Clementi

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 837

ISBN-13: 3642570798

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Neuronal nicotinic receptors are key molecules for signal transduction in a number of neuronal pathways. They are widely distributed in the brain and are known to be involved in cognitive tasks, including learning and memory, in smoking addiction and in several brain diseases, such as Alzheimer's and Parkinson's dementias, schizophrenia, and epilepsy. This book provides a comprehensive review of the field, starting with a historical perspective and dealing with the molecular structure of these receptors, their biophysical and pharmacological properties, their distribution in central and peripheral nervous systems, and their major involvement in brain functions. Particular emphasis is paid to drugs (both new and old) that are useful in the diagnosis and treatment of diseases involving neuronal nicotinic receptors. Finally, the relevance of these receptors in smoking addiction is carefully evaluated, together with future trends and the latest results.


CNS Neurotransmitters and Neuromodulators

CNS Neurotransmitters and Neuromodulators

Author: Trevor W. Stone

Publisher: CRC Press

Published: 2020-10-28

Total Pages: 278

ISBN-13: 1000142116

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The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject. This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.


Basic Physiology for Anaesthetists

Basic Physiology for Anaesthetists

Author: David Chambers

Publisher: Cambridge University Press

Published: 2019-07-25

Total Pages: 469

ISBN-13: 1108463991

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Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.


Insect Nicotinic Acetylcholine Receptors

Insect Nicotinic Acetylcholine Receptors

Author: Steeve Hervé Thany

Publisher: Springer Science & Business Media

Published: 2011-01-11

Total Pages: 127

ISBN-13: 1441964452

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The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.


Cellular and Molecular Neurophysiology

Cellular and Molecular Neurophysiology

Author: Constance Hammond

Publisher: Academic Press

Published: 2014-12-30

Total Pages: 444

ISBN-13: 0123973228

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Cellular and Molecular Neurophysiology, Fourth Edition, is the only up-to-date textbook on the market that focuses on the molecular and cellular physiology of neurons and synapses. Hypothesis-driven rather than a dry presentation of the facts, the book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. This new edition explains the molecular properties and functions of excitable cells in detail and teaches students how to construct and conduct intelligent research experiments. The content is firmly based on numerous experiments performed by top experts in the field This book will be a useful resource for neurophysiologists, neurobiologists, neurologists, and students taking graduate-level courses on neurophysiology. - 70% new or updated material in full color throughout, with more than 350 carefully selected and constructed illustrations - Fifteen appendices describing neurobiological techniques are interspersed in the text


Autonomic Neurology

Autonomic Neurology

Author: Eduardo E. Benarroch

Publisher: Oxford University Press

Published: 2014-04-03

Total Pages: 314

ISBN-13: 0199920206

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The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.


Autonomic Failure

Autonomic Failure

Author: C. J. Mathias

Publisher: Oxford University Press, USA

Published: 1999

Total Pages: 562

ISBN-13: 9780192628510

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This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.


Encyclopedia of Clinical Neuropsychology

Encyclopedia of Clinical Neuropsychology

Author: Jeffrey Kreutzer

Publisher: Springer Science & Business Media

Published: 2010-09-29

Total Pages: 0

ISBN-13: 0387799478

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Clinical neuropsychology is a rapidly evolving specialty whose practitioners serve patients with traumatic brain injury, stroke and other vascular impairments, brain tumors, epilepsy and nonepileptic seizure disorders, developmental disabilities, progressive neurological disorders, HIV- and AIDS-related disorders, and dementia. . Services include evaluation, treatment, and case consultation in child, adult, and the expanding geriatric population in medical and community settings. The clinical goal always is to restore and maximize cognitive and psychological functioning in an injured or compromised brain. Most neuropsychology reference books focus primarily on assessment and diagnosis, and to date none has been encyclopedic in format. Clinicians, patients, and family members recognize that evaluation and diagnosis is only a starting point for the treatment and recovery process. During the past decade there has been a proliferation of programs, both hospital- and clinic-based, that provide rehabilitation, treatment, and treatment planning services. This encyclopedia will serve as a unified, comprehensive reference for professionals involved in the diagnosis, evaluation, and rehabilitation of adult patients and children with neuropsychological disorders.