New Insights Into Adult Neurogenesis and Neurodegeneration: Challenges for Brain Repair
Author: Jose Angel Morales-Garcia
Publisher: Frontiers Media SA
Published: 2022-04-04
Total Pages: 284
ISBN-13: 2889749088
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Author: Jose Angel Morales-Garcia
Publisher: Frontiers Media SA
Published: 2022-04-04
Total Pages: 284
ISBN-13: 2889749088
DOWNLOAD EBOOKAuthor: Anatoli I. Yashin
Publisher:
Published: 2015
Total Pages: 0
ISBN-13: 9783318027297
DOWNLOAD EBOOKAging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.
Author: Steven C. Cramer
Publisher: Cambridge University Press
Published: 2010-10-28
Total Pages: 307
ISBN-13: 1139490656
DOWNLOAD EBOOKIncreasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Author: Helen E. Scharfman
Publisher: Elsevier Science Serials
Published: 2007
Total Pages: 787
ISBN-13: 9780444530158
DOWNLOAD EBOOKA compilation of the fundamentals of the dentate gyrus, an area of the brain of intense scientific interest due to its capacity for plasticity.
Author: Catherine Belzung
Publisher: Springer Science & Business Media
Published: 2014-07-08
Total Pages: 447
ISBN-13: 364236232X
DOWNLOAD EBOOKThis volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Author: Rocío Fernández-Ballesteros
Publisher: Cambridge University Press
Published: 2019-01-24
Total Pages: 969
ISBN-13: 1108641431
DOWNLOAD EBOOKRecent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.
Author: MallIck/Inoue
Publisher: CRC Press
Published: 1999-06-29
Total Pages: 450
ISBN-13: 9780824703226
DOWNLOAD EBOOKThis reference also includes nine color plates. Written by leading international scientists in the field, this comprehensive and up-to-date reference provides detailed coverage of various aspects of rapid eye movement sleep (REMS)-including phylogeny and evolution, ontogeny, neurophysiological and neurochemical phenomena, molecular processes, behavioral and physiological changes due to deprivation, and hypotheses on the neurodynamics of REMS. Examining the relationship between the neocortex in mammals and birds in the evolution of REM sleep, Rapid Eye Movement Sleep considers the roles of REMS in the maturation of the brain reveals a new theory that challenges the assumption that REM is solely initiated by bulbar mechanisms in intact animals explores experimental studies of REMS atonia and the mechanisms underlying tonic and phasic muscle atonia describes the cellular and molecular mechanisms and function of pontine ponto-geniculo-occipatal waves during REMS details the role of nitric oxide in the regulation of REMS summarizes new evidence on which neurotransmitters are responsible for the REMS generating mechanism presents an overview of several endogenous sleep substances that may positively or negatively regulate REMS and more. Rapid Eye Movement Sleep serves as essential reading for all researchers and clinicians in the study of sleep science, particularly physiologists and biologists; neurologists, neuropsychiatrists, psychiatrists, and psychologists; anesethiologists; and pharmacologists.
Author: Ayanna K. Thomas
Publisher: Cambridge University Press
Published: 2020-05-28
Total Pages: 1019
ISBN-13: 1108690742
DOWNLOAD EBOOKDecades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.
Author: Mario F. Wulliman
Publisher: Birkhäuser
Published: 2012-12-06
Total Pages: 142
ISBN-13: 3034889798
DOWNLOAD EBOOKAuthor: William M. Reichert
Publisher: CRC Press
Published: 2007-12-17
Total Pages: 300
ISBN-13: 1420009303
DOWNLOAD EBOOKDespite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel