New Aspects of Storage and Release Mechanisms of Catecholamines
Author: Hans-Joachim Schümann
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 504
ISBN-13: 3642497470
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Neural Plasticity and Memory
Author: Federico Bermudez-Rattoni
Publisher: CRC Press
Published: 2007-04-17
Total Pages: 368
ISBN-13: 1420008412
DOWNLOAD EBOOKA comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Caffeine for the Sustainment of Mental Task Performance
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2002-01-07
Total Pages: 172
ISBN-13: 0309082587
DOWNLOAD EBOOKThis report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Catecholamines
Author: Hermann Blaschko
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 1073
ISBN-13: 3642652492
DOWNLOAD EBOOKCatecholamines 1922 -1971 H. BLASCHKO Adrenaline and related substances were discussed in the 1924 edition of Hefl'ter's Handbook by PAUL TRENDELENBURG. On 164 pages he described what was then known not only of adrenaline and its closest relatives but also of the sympathomimetic compounds such as tyramine and ephedrine. When the present Editors of the Handbook entrusted us with the task of editing the present Volume it was decided to restrict it to adrenaline and the other naturally occurring catecholamines. The sympathomimetic amines in general will be discussed only in their relation to the catecholamines. Since TRENDELENBURG completed his review this field has undergone an enormous expansion. There has been a wealth of new findings, and a succession of new ideas. The new theories that have been built into contemporary thought will be fully discussed in the succeeding contributions. But many of the hypotheses that have been put forward since 1924 have long been discarded and yet, they have often led to important observations that we still consider as valid.
Disorders of Blood Pressure Regulation
Author: Adel E. Berbari
Publisher: Springer
Published: 2018-01-25
Total Pages: 858
ISBN-13: 3319599186
DOWNLOAD EBOOKThis book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.
Antihypertensive Agents
Author: F. Gross
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 791
ISBN-13: 3642663095
DOWNLOAD EBOOKBasic Neurochemistry
Author: R. Wayne Albers
Publisher: Academic Press
Published: 2011-11-02
Total Pages: 1121
ISBN-13: 0080959016
DOWNLOAD EBOOKBasic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475
Presynaptic Receptors and Neuronal Transporters
Author: S.Z. Langer
Publisher: Elsevier
Published: 2013-10-22
Total Pages: 373
ISBN-13: 1483278220
DOWNLOAD EBOOKAdvances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.
The Release of Catecholamines from Adrenergic Neurons
Author: David M. Paton
Publisher: Elsevier
Published: 2016-06-06
Total Pages: 406
ISBN-13: 1483136523
DOWNLOAD EBOOKThe Release of Catecholamines from Adrenergic Neurons focuses on the processes involved in determining the release of catecholamines from neurons, noting the influence of alcohols, analgesics, and acids in the release. The selection first discusses biochemical and ultrastructural studies of the mechanism of release, as well as release of constituents of noradrenergic vesicles upon nerve stimulation; constituents of noradrenergic vesicles; and mechanism of release. The book then takes a look at the role of calcium in catecholamine release from adrenergic nerve terminals and presynaptic adrenoceptors and regulation of release. Topics include calcium-dependent versus calcium-independent noradrenaline release; differences between the presynaptic and postsynaptic alpha-adrenoceptors; and influence of neuronal uptake of noradrenaline on the negative feedback mechanism mediated by presynaptic alpha-adrenoceptors. The publication reviews presynaptic muscarine receptors and inhibition of release, including muscarinic inhibition of noradrenaline release evoked by electrical stimulation of sympathetic nerves; effect of muscarinic agonists on noradrenaline releasing procedures independent of calcium ions; and possible physiological and pharmacological significance of the muscarinic inhibitory mechanism. The text also ponders on the role of prostaglandins, cyclic adenosine monophate, analgesics, peptides, acids, anesthetics, and alcohols in the release. The selection is a dependable reference for readers interested in the study of the release of catecholamines from adrenergic neurons.
Pheochromocytomas, Paragangliomas and Disorders of the Sympathoadrenal System
Author: Lewis Landsberg
Publisher: Humana Press
Published: 2018-05-03
Total Pages: 224
ISBN-13: 3319770489
DOWNLOAD EBOOKProviding a comprehensive review of the most up-to-date evidence, this book presents the latest biology, diagnosis and management for pheochromocytomas, paragangliomas and related disorders of the sympathoadrenal system. Many new areas, including genetic syndromes, have evolved, and these are insufficiently appreciated among practitioners. A discussion of the basics of catecholamine biology sets the stage for presentations of the pathology, clinical features, and diagnosis of these tumors, including localization and imaging. Medical, anesthetic and surgical management of pheochromocytomas and paragangliomas follow, including case material. Additional chapters discuss pheochromocytoma in pediatrics and in pregnancy, both pure and hypoglycemia-associated autonomic failure, and the role of the sympathetic nervous system in hypertension. /divThese diseases are relatively rare, but many, if not most, go undiagnosed during life: If promptly diagnosed and appropriately treated, they are usually completely curable; if undiagnosed or mistreated, they are typically terminal. Bringing the most current knowledge to bear, Pheochromocytomas, Paragangliomas and Disorders of the Sympathoadrenal System will be a valuable resource for practicing endocrinologists, endocrine surgeons, internists and endocrine fellows faced with diagnosing and managing these conditions.
