Neurobiology of Motor Control

Neurobiology of Motor Control

Author: Scott L. Hooper

Publisher: John Wiley & Sons

Published: 2017-06-12

Total Pages: 512

ISBN-13: 1118873343

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A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.


Neural Control of Rhythmic Movements in Vertebrates

Neural Control of Rhythmic Movements in Vertebrates

Author: Avis H. Cohen

Publisher: Wiley-Interscience

Published: 1988-02-26

Total Pages: 520

ISBN-13:

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Electroreception Edited by Theodore Holmes Bullock and Walter Heiligenberg Presents recent findings in the research on modality of animal perception, particularly the ability to sense feeble electrical fields. Includes a new treatment of electric organs and their control, examination of receptors and their ionic mechanisms, and discussion of regeneration of the spinal cord. Uses electric fish as models. 1986 (0 471-81800-3) 722 pp. Neurobiology of Taste and Smell Thomas E. Finger and Wayne L. Silver A survey of subdisciplines within the field of neurobiology and an overview of current issues, recent findings, and future research, and an excellent introduction to the specific study of the chemical senses, including olfactory, vomeronasal, and gustatory systems. 1987 (0 471-81799-6) 449 pp. Higher Brain Functions Recent Explorations of the Brain’s Emergent Properties Edited by Steven P. Wise Pushing at the frontiers of knowledge, the best minds in the field of neurophysiology develop original ideas first presented in a monograph by Evarts, Shinoda, and Wise, Neurophysiological Approaches to Higher Brain Functions. Organized into three sections, Motor Aspects of Higher Brain Function, Effects of Preparatory Set, and Cerebral Organization, this volume explores important and interesting research directed toward questions concerning higher brain functions that lie beyond the traditional concerns of sensor and motor physiology. 1987 (0 471-01111-8) 384 pp. Synaptic Function Edited by Gerald M. Edelman, W. Einar Gall, and W. Maxwell Cowan Examines synaptic function by focusing on five areas—biochemical and biophysical mechanisms of change in pre-and postsynaptic cells; the neurochemicstry of transmitters and their release; the interactions of cells in small networks; synaptic plasticity related to long-term changes; and theoretical models of synaptic function. 1987 (0 471-85557-X) 944 pp.


Neural Control of Movement

Neural Control of Movement

Author: W.R. Ferrell

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 295

ISBN-13: 1461519853

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Presented with a choice of evils, most would prefer to be blinded rather than to be unable to move, immobilized in the late stages of Parkinson's disease. Yet in everyday life, as in Neuroscience, vision holds the centre of the stage. The conscious psyche watches a private TV show all day long, while the motor system is left to get on with it "out of sight and out of mind. " Motor skills are worshipped at all levels of society, whether in golf, tennis, soccer, athletics or in musical performance; meanwhile the subconscious machinery is ignored. But scientifically there is steady advance on a wide front, as we are reminded here, from the reversal of the reflexes of the stick insects to the site of motor learning in the human cerebral cortex. As in the rest of Physiology, evolution has preserved that which has already worked well; thus general principles can often be best discerned in lower animals. No one scientist can be personally involved at all levels of analysis, but especially for the motor system a narrow view is doomed from the outset. Interaction is all; the spinal cord has surrendered its autonomy to the brain, but the brain can only control the limbs by talking to the spinal cord in a language that it can understand, determined by its pre-existing circuitry; and both receive a continuous stream of feedback from the periphery.


Neuroscience in the 21st Century

Neuroscience in the 21st Century

Author: Donald W. Pfaff

Publisher: Springer

Published: 2016-10-27

Total Pages: 0

ISBN-13: 9781493934737

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Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.


Presynaptic Inhibition and Neural Control

Presynaptic Inhibition and Neural Control

Author: Pablo Rudomin

Publisher:

Published: 1998

Total Pages: 474

ISBN-13: 9780195105162

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This is a timely review of the mechanisms underlying the presynaptic control of synaptic transmission and the role they play in sensory and motor behavior. Early chapters offer a detailed account of the anatomy, biophysics, and physiology of synaptic transmission at the peripheral and central synapses, focusing on the presynaptic control of transmitter release. Later chapters explore the organization of neural pathways leading to the presynaptic inhibition of transmitter release in segmental reflex pathways. A final section provides examples of the operation of presynaptic control mechanisms during specific sensory and motor functions in mammals, including humans. Integrating synaptic transmission and CNS functions at the systems level, this volume will be of particular interest to researchers studying both areas.


Neurons, Networks, and Motor Behavior

Neurons, Networks, and Motor Behavior

Author: Paul S. G. Stein

Publisher: MIT Press

Published: 1997

Total Pages: 330

ISBN-13: 9780262692274

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Recent advances in motor behavior research rely on detailed knowledge of the characteristics of the neurons and networks that generate motor behavior. At the cellular level, Neurons, Networks, and Motor Behavior describes the computational characteristics of individual neurons and how these characteristics are modified by neuromodulators. At the network and behavioral levels, the volume discusses how network structure is dynamically modulated to produce adaptive behavior. Comparisons of model systems throughout the animal kingdom provide insights into general principles of motor control. Contributors describe how networks generate such motor behaviors as walking, swimming, flying, scratching, reaching, breathing, feeding, and chewing. An emerging principle of organization is that nervous systems are remarkably efficient in constructing neural networks that control multiple tasks and dynamically adapt to change.The volume contains six sections: selection and initiation of motor patterns; generation and formation of motor patterns: cellular and systems properties; generation and formation of motor patterns: computational approaches; modulation and reconfiguration; short-term modulation of pattern generating circuits; and sensory modification of motor output to control whole body orientation.


The Neural Control of Movement

The Neural Control of Movement

Author: Patrick J. Whelan

Publisher: Academic Press

Published: 2020-08-12

Total Pages: 486

ISBN-13: 0128172754

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From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs. The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control. - Provides practice details on model systems, approaches, and analysis approaches related to movement control - Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control - Written for neuroscientists interested in movement control, especially movement disorders like Parkinson's, MS, spinal cord injury, and stroke