Nanobiosensors for point-of-care medical diagnostics
Nanobiosensors for point-of-care medical diagnostics

Author: Manashjit Gogoi

Publisher: Springer Nature

Published: 2023-01-01

Total Pages: 287

ISBN-13: 9811951411

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This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.

Nanobiosensors
Nanobiosensors

Author: Alexandru Grumezescu

Publisher: Academic Press

Published: 2016-09-28

Total Pages: 928

ISBN-13: 0128043725

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Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. - Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection - Provides application methods and techniques for research analysis for bacteriological detection and food testing - Presents studies using analytical tools to improve food safety and quality analysis

Nanobiosensors for Personalized and Onsite Biomedical Diagnosis
Nanobiosensors for Personalized and Onsite Biomedical Diagnosis

Author: Pranjal Chandra

Publisher: IET

Published: 2016-07-21

Total Pages: 637

ISBN-13: 1849199507

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The critical goal of nanobiosensors is to detect any biochemical and/or biophysical signal related to a specific disease at the level of a single or few molecules. Nanobiosensors have been successful for in vitro as well as in vivo detection of several biomolecules. It is expected that this technology will revolutionize point-of-care and personalized diagnostics, and will be extremely applicable for early disease detection. This book starts with a brief introduction of the biosensors and then focuses mainly on the emerging nanobiosensor technologies which are geared towards onsite clinical applications and those which can be used as a personalized diagnostic device. Written by an international team of researchers who are actively developing these technologies, Nanobiosensors for Personalized and Onsite Biomedical Diagnosis covers the latest advances in the field of biosensors and biosensing applications. This important book includes an assessment of some current and emerging technologies for detecting protein biomarkers and other potential cancer biomarkers and is essential reading for researchers and graduate students in the field. Medics including radiologists and clinicians will also find it invaluable.

Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics
Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics

Author: Gorachand Dutta

Publisher: Springer Nature

Published: 2022-12-02

Total Pages: 252

ISBN-13: 9811971307

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This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. ​

Biosensor Based Advanced Cancer Diagnostics
Biosensor Based Advanced Cancer Diagnostics

Author: Raju Khan

Publisher: Academic Press

Published: 2021-08-25

Total Pages: 439

ISBN-13: 0128236515

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Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. - Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers - Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications - Offers an insight into how to develop cost-effective diagnostics for early detection of cancer

Advanced Nanomaterials for Point of Care Diagnosis and Therapy
Advanced Nanomaterials for Point of Care Diagnosis and Therapy

Author: Sushma Dave

Publisher: Elsevier

Published: 2022-03-11

Total Pages: 596

ISBN-13: 0323900666

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Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite. Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field. Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform

Biointerface Engineering: Prospects in Medical Diagnostics and Drug Delivery
Biointerface Engineering: Prospects in Medical Diagnostics and Drug Delivery

Author: Pranjal Chandra

Publisher: Springer Nature

Published: 2020-07-21

Total Pages: 259

ISBN-13: 9811547904

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This book provides detailed information on the surface and surface chemistry of various biointerfaces for the understanding and development of biosensors, biocompatible devices, and drug delivery systems. It highlights the role of interfacial phenomena towards the behaviour of biomolecules on different surfaces and their significance in recent applications. The book also addresses various surface engineering techniques for the modification of biomaterials that are implemented for improving biocompatibility. It provides an updated scientific concept of various interactions of biological systems with surfaces/modified surfaces at the molecular and cellular level. The chapters include various in-vitro, in-vivo, ex-vivo models to illustrate various aspects of Biointerface Engineering. Finally, the book elucidates troubleshooting strategies and future prospects of Biointerface Engineering in Medical Diagnostics and Drug Delivery.

Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis
Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis

Author: Pranjal Chandra

Publisher: Springer

Published: 2018-01-22

Total Pages: 0

ISBN-13: 9789811047251

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This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Nanobioanalytical Approaches to Medical Diagnostics
Nanobioanalytical Approaches to Medical Diagnostics

Author: Pawan Kumar Maurya

Publisher: Woodhead Publishing

Published: 2022-06-21

Total Pages: 432

ISBN-13: 0323851657

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Nanobioanalytical Approaches to Medical Diagnostics reviews a range of nanobiomaterials and bioanalytical nano-devices for medical diagnostics. Nanobiomaterials and nano-devices are used in various bioanalytical and biochemical systems to provide real-time, point-of-care diagnostics. The specialized properties of nanoparticles allow them to be engineered and adapted to produce the required effect within a bioanalytical or biochemical system – offering targeted and detailed diagnostic results in a range of biomedical applications. This book covers both traditional biochemical and modern, combined nano-approaches to medical diagnostics. Chapters detail a range of in vitro, in vivo and ex vivo models for nanobioanalytics, including DNA and peptide-based, erythrocyte, microfluidic and more. In addition, sections also look at various different medical diagnostic applications, such as in cancer detection, infectious disease diagnosis and blood glucose sensing. - Covers core principles and nano-approaches in bioanalytics for medical diagnostics - Details a range of in vitro, in vivo and ex vivo models for nanobioanalytics, including spectroscopic analysis, erythrocyte models, microfluidics, and more - Appeals to an interdisciplinary readership, spanning the fields of materials science, biomedical engineering and biochemical engineering

Nanosensors for Smart Manufacturing
Nanosensors for Smart Manufacturing

Author: Sabu Thomas

Publisher: Elsevier

Published: 2021-06-10

Total Pages: 634

ISBN-13: 0128236523

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Nanosensors for Smart Manufacturing provides information on the fundamental design concepts and emerging applications of nanosensors in smart manufacturing processes. In smart production, if the products and machines are integrated, embedded, or equipped with sensors, the system can immediately collect the current operating parameters, predict the product quality, and then feed back the optimal parameters to machines in the production line. In this regard, smart sensors and their wireless networks are important components of smart manufacturing. Nanomaterials-based sensors (nanosensors) offer several advantages over their microscale counterparts, including lower power consumption, fast response time, high sensitivity, lower concentration of analytes, and smaller interaction distance between sensors and products. With the support of artificial intelligence (AI) tools such as fuzzy logic, genetic algorithms, neural networks, and ambient intelligence, sensor systems have become smarter. This is an important reference source for materials scientists and engineers who want to learn more about how nanoscale sensors can enhance smart manufacturing techniques and processes. - Outlines the smart nanosensor classes used in manufacturing applications - Shows how nanosensors are being used to make more efficient manufacturing systems - Assesses the major obstacles to designing nanosensor-based manufacturing systems at an industrial scale