This book addresses challenges for the development of a point-of-care-test platform. The book describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection in real samples. The main challenges of point-of-care testing require implementing complex analytical methods into low-cost technologies. This is particularly true for countries with less developed healthcare infrastructure. Washing-free, Lab-on-Chip, and Lab-on-PCB techniques are very simple and innovative for point-of-care device development. The redox cycling technology detects several interesting targets at the same time on a printed chip. The proposed areas are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics and electrical engineering, health care, and manufacturing. This book focuses on recent advances and different research issues in the nanobiotechnology-enabled biosensor technology and also seeks out theoretical, methodological, well-established, and validated empirical work dealing with these different topics.
Novel Nanostructured Materials for Electrochemical Bio-sensing Applications presents a detailed overview into the fabrication of electrochemical bio-sensing devices. The book addresses the challenges and opportunities relating to sustainable and biocompatible sensors from food, water and wearable applications to the various nanostructured biocompatible materials required for sensor fabrication. In addition, it explores the connection between nanomaterials and sensors and takes into consideration different and novel approaches such as toxic materials monitoring and health issues correlated with the use of nanomaterials. Users will find exciting insight into innovations in nanostructured electrochemical biosensing. By providing its audience with fundamentals, limitations, challenges, future perspectives and practical sustainability, this book will serve as a reference source researchers and engineers within analytical chemistry and electrochemistry. - Showcases the latest progress in new nanostructured materials, bio-sensing types and applications - Provides a comparative vision of electrochemical bio-sensing with other biosensors - Discusses the economics, commercialization, toxicity and life line aspects of electrochemical biosensors
We are proposing this comprehensive volume aimed at bridging and bonding of the theory and practical experiences for the elimination of a broad range of pollutants from various types of water and soil utilizing innovative nanotechnologies, biotechnologies and their possible combinations. Nowadays, a broad range of contaminants are emerging from the industry (and also representing old ecological burdens). Accidents and improper wastewater treatment requires a fast, efficient and cost-effective approach. Therefore, several innovative technologies of water and soil treatments have been invented and suggested in a number of published papers. Out of these, some nanotechnologies and biotechnologies (and possibly also their mutual combinations) turned out to be promising for practical utilization – i.e., based on both extensive laboratory testing and pilot-scale verification. With respect to the diverse character of targeted pollutants, the key technologies covered in this book will include oxidation, reduction, sorption and/or biological degradation. In relation to innovative technologies and new emerging pollutants mentioned in this proposed book, an important part will also cover the ecotoxicity of selected pollutants and novel nanomaterials used for remediation. Thus, this work will consist of 8 sections/chapters with a technical appendix as an important part of the book, where some technical details and standardized protocols will be clearly presented for their possible implementation at different contaminated sites. Although many previously published papers and books (or book chapters) are devoted to some aspects of nano-/biotechnologies, here we will bring a first complete and comprehensive treatise on the latest progress in innovative technologies with a clear demonstration of the applicability of particular methods based on results of the authors from pilot tests (i.e., based on the data collected within several applied projects, mainly national project “Environmentally friendly nanotechnologies and biotechnologies in water and soil treatment” of the Technology Agency of the Czech Republic, and 7FP project NANOREM: “Taking Nanotechnological Remediation Processes from Lab Scale to End User Applications for the Restoration of a Clean Environment”). This multidisciplinary book will be suitable for a broad audience including environmental scientists, practitioners, policymakers and toxicologists (and of course graduate students of diverse fields – material science, chemistry, biology, geology, hydrogeology, engineering etc.).
This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions. It describes the consequences of these interactions on other biological aspects like flora and fauna of the niche, cell proliferation, etc. The book provides information about the novel and eco-friendly nanoparticle synthesis methods, such as continuous synthesis of nanoparticles using microbial cells. Additionally, the book discusses nanoparticles' potential impact in different areas of biological sciences like food, medicine, agriculture, and the environment. Due to their advanced physicochemical properties, nanoparticles have revolutionized biomedical and pharmaceutical sciences. Inside the biological milieu, nanoparticles interact with different moieties to adopt stable shape, size, and surface functionalities and form nano-biomolecular complexes. The interaction pattern at the interface form complexes determines the fate of interacting biomolecules and nanoparticles inside the biological system. Understanding the interaction pattern at the nano-bio interface is crucial for the safe use of nanoparticles in natural sciences. This book rightly addresses all questions about the interaction and the ensuing structure and function of these nano-biomolecular complexes. This book caters to students and researchers in the area of biotechnology, microbiology, and pharmaceutical sciences.
Presents recent challenges related to new forms of pollution from industries and discusses adequate state-of-the-art technologies capable to remediate such forms of pollution. Over the past few decades the boom in the industrial sector has contributed to the release in the environment of pollutants that have no regulatory status and which may have significant impact on the health of humans and animals. These pollutants also referred to as "emerging pollutants", are mostly aromatic compounds which derive from excretion of pharmaceutical, industrial effluents and municipal discharge. It is recurrent these days to find water treatment plants which no longer produce water that fits the purpose of domestic consumption based on newly established guidelines. This situation has prompted water authorities and researchers to develop tools for proper prediction and control of the dispersion of pollutants in the environment to ensure that appropriate measures are taken to prevent the occurrence of outbreaks due to sudden load of these pollutants in the water system. The chapters in this book cover a wide range of nano and bio-based techniques that have been designed for the real time detection of emerging contaminants in environmental water sources, geochemical models that are continuously improved for the prediction of inorganic contaminants migration from the mine solid wastes into ground and surface waters. Remediation strategies are also discussed and include effective techniques based on nanotechnology, advanced membrane filtration, oxidative and bio-degradation processes using various types of nanocatalysts, biocatalysts or supporting polymer matrices which are under advanced investigations for their implementation at large scale for the removal of recalcitrant pollutants from polluted water. Nano and Bio-Based Technologies for Wastewater Treatment: Prediction and Control Tools for the Dispersion of Pollutants in the Environment is divided is two sections. The first section covers the occurrence of emerging pollutants in environmental water while the second section covers state-of-the-art research on the removal of emerging pollutants from water using sustainable technologies. A total of 13 chapters addressing various topics related to the two sections are essentially based on recent developments in the respective field which could have a significant impact on the enhancement of the performance of wastewater treatment plants around the world, and especially in developing countries where access to clean and safe water remains a daily challenge.
Nanobioelectrochemistry covers the modern aspects of bioelectrochemistry, nanoscience and materials science. The combination of nanostructured materials and biological molecules enables the development of biodevices capable to detect specific substances. Furthermore, by using the bioelectrochemistry approach, the interaction between bio-systems and nanostructured materials can be studied at the molecular level, where several mechanisms of molecular behavior are elucidate from redox reactions. The combination of biological molecules and novel nanomaterials components is of great importance in the process of developing new nanoscale devices for future biological, medical and electronic applications. This book describes some of the different electrochemical techniques that can be used to study new strategies for patterning electrode surfaces with enzymes, organelles, cells and biomimetic systems. Also, it focuses on how enzymes and microorganisms can be used as biological catalysts in fuel cells for green power generation. By bringing together these different aspects of nanobioelectrochemistry, this book provides a valuable source of information for many students and scientists.
This handbook comprehensively reviews different nanomaterials and modern electrochemical approaches used in the point-of-care analysis of biomolecules. It describes the importance, significance, and application of various kinds of smart nanomaterials and their integration with modern electrochemical techniques for the point-of-care diagnosis of biologically important biomolecules. The interaction between bio-systems and nanomaterials have been discussed in this book using advanced electrochemical methods and characterizing techniques. It describes the combination of classical and modern methodologies for the synthesis of metal nanoparticles/nanoclusters and modern electrochemical techniques for the early-stage detection and point-of-care diagnosis of cancer and other infectious disease such as SARS, influenza, tuberculosis (TB), and hepatitis. Finally, the book provides an accessible and readable summary of the use of nanomaterial for understanding the electrochemical reaction taking place at nano-bio interfaces in electrochemical biomolecular detection and analysis. The book bridges the gap and strengthens the relationship between electrochemists, material scientists, and biomolecular scientists who are directly or indirectly associated with the field of such point-of-care diagnostics.
Advanced Nanomaterials and Nanocomposites for Bioelectrochemical Systems covers advancements in nanomaterial and nanocomposite applications for microbial fuel cells. One of the advantages of using microbial fuel cells is the simultaneous treatment of wastewater and the generation of electricity from complex organic waste and biomass, which demonstrates that microbial fuel cells are an active area of frontier research. The addition of microorganisms is essential to enhance the reaction kinetics. This type of fuel cell helps to convert complex organic waste into useful energy through the metabolic activity of microorganisms, thereby generating energy. By incorporating nano-scale fillers into the nanocomposite matrix, the performance of the anode material can be improved. This is an important reference source for materials scientists and engineers who want to learn more about how nanotechnology is being used to create more efficient fuel cells. - Describes the major nanomaterials and nanocomposites used in microbial fuel cells - Explains how microbial fuel cells are being used in renewable energy applications - Assesses the challenges of manufacturing nanomaterials for microbial fuel cells on an industrial scale
Dynamics of Advanced Sustainable Nanomaterials and Their Related Nanocomposites at the Bio-Nano Interface highlights the most recent research findings (conducted over the last 5-6 years) on the dynamics of nanomaterials, including their multifaceted, advanced applications as sustainable materials. In addition, special attributes of these materials are discussed from a mechanistic and application point-of-view, including their sustainability and interfacial interactions at the bio-nano interface and different applications. This book presents an important reference resource on advanced sustainable nanomaterials for chemical, nano-, and materials technologists who are looking to learn more about advanced nanocomposites with sustainable attributes. Finally, the book examines the emerging market for sustainable materials and their advanced applications, with a particular focus on the bio-nano interface and their future outlook. - Features detailed information on the fundamentals of bio-nano interfacial interactions in sustainable nanomaterials - Includes advanced applications of these materials that will help the end user select the appropriate materials for their desired application - Features extensive information on the dynamics of these materials, helping the end user extend their work into new applications
Bioelectrochemistry is a fast growing field at the interface between electrochemistry and other sciences such as biochemistry, analytical chemistry and medicinal chemistry. In the recent years, the methods and the understanding of the fundamentals have seen significant progress, which has led to rapid development in the field. Here, the expert editors have carefully selected contributions to best reflect the latest developments in this hot and rapidly growing interdisciplinary topic. The resulting excellent and timely overview of this multifaceted field covers recent methodological advances, as well as a range of new applications for analytical detection, drug screening, tumor therapy, and for energy conversion in biofuel cells. This book is a must-have for all Electrochemists, Biochemists, Analytical Chemists, and Medicinal Chemists.
