Surrogates
Surrogates

Author: Robert B. Gramacy

Publisher: CRC Press

Published: 2020-03-10

Total Pages: 560

ISBN-13: 1000766209

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Computer simulation experiments are essential to modern scientific discovery, whether that be in physics, chemistry, biology, epidemiology, ecology, engineering, etc. Surrogates are meta-models of computer simulations, used to solve mathematical models that are too intricate to be worked by hand. Gaussian process (GP) regression is a supremely flexible tool for the analysis of computer simulation experiments. This book presents an applied introduction to GP regression for modelling and optimization of computer simulation experiments. Features: • Emphasis on methods, applications, and reproducibility. • R code is integrated throughout for application of the methods. • Includes more than 200 full colour figures. • Includes many exercises to supplement understanding, with separate solutions available from the author. • Supported by a website with full code available to reproduce all methods and examples. The book is primarily designed as a textbook for postgraduate students studying GP regression from mathematics, statistics, computer science, and engineering. Given the breadth of examples, it could also be used by researchers from these fields, as well as from economics, life science, social science, etc.

Bayesian Networks
Bayesian Networks

Author: Olivier Pourret

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 446

ISBN-13: 9780470994542

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Bayesian Networks, the result of the convergence of artificial intelligence with statistics, are growing in popularity. Their versatility and modelling power is now employed across a variety of fields for the purposes of analysis, simulation, prediction and diagnosis. This book provides a general introduction to Bayesian networks, defining and illustrating the basic concepts with pedagogical examples and twenty real-life case studies drawn from a range of fields including medicine, computing, natural sciences and engineering. Designed to help analysts, engineers, scientists and professionals taking part in complex decision processes to successfully implement Bayesian networks, this book equips readers with proven methods to generate, calibrate, evaluate and validate Bayesian networks. The book: Provides the tools to overcome common practical challenges such as the treatment of missing input data, interaction with experts and decision makers, determination of the optimal granularity and size of the model. Highlights the strengths of Bayesian networks whilst also presenting a discussion of their limitations. Compares Bayesian networks with other modelling techniques such as neural networks, fuzzy logic and fault trees. Describes, for ease of comparison, the main features of the major Bayesian network software packages: Netica, Hugin, Elvira and Discoverer, from the point of view of the user. Offers a historical perspective on the subject and analyses future directions for research. Written by leading experts with practical experience of applying Bayesian networks in finance, banking, medicine, robotics, civil engineering, geology, geography, genetics, forensic science, ecology, and industry, the book has much to offer both practitioners and researchers involved in statistical analysis or modelling in any of these fields.

Systems Biology and Synthetic Biology
Systems Biology and Synthetic Biology

Author: Pengcheng Fu

Publisher: John Wiley & Sons

Published: 2009-08-13

Total Pages: 672

ISBN-13: 9780470437971

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The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.

Modern Issues and Methods in Biostatistics
Modern Issues and Methods in Biostatistics

Author: Mark Chang

Publisher: Springer Science & Business Media

Published: 2011-07-15

Total Pages: 316

ISBN-13: 144199842X

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Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.

Catalyzing Inquiry at the Interface of Computing and Biology
Catalyzing Inquiry at the Interface of Computing and Biology

Author: National Research Council

Publisher: National Academies Press

Published: 2006-01-01

Total Pages: 469

ISBN-13: 030909612X

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Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

The Sonification Handbook
The Sonification Handbook

Author: Thomas Hermann

Publisher: Logos Verlag Berlin

Published: 2011

Total Pages: 0

ISBN-13: 9783832528195

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This book is a comprehensive introductory presentation of the key research areas in the interdisciplinary fields of sonification and auditory display. Chapters are written by leading experts, providing a wide-ranging coverage of the central issues, and can be read from start to finish, or dipped into as required. Sonification conveys information by using non-speech sounds. To listen to data as sound and noise can be a surprising new experience with diverse applications ranging from novel interfaces for visually impaired people to data analysis problems in many scientific fields. This book gives a solid introduction to the field of auditory display, the techniques for sonification, suitable technologies for developing sonification algorithms, and the most promising application areas. The book is accompanied by an online repository of sound examples.

Pattern Classification
Pattern Classification

Author: Richard O. Duda

Publisher: John Wiley & Sons

Published: 2012-11-09

Total Pages: 680

ISBN-13: 111858600X

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The first edition, published in 1973, has become a classicreference in the field. Now with the second edition, readers willfind information on key new topics such as neural networks andstatistical pattern recognition, the theory of machine learning,and the theory of invariances. Also included are worked examples,comparisons between different methods, extensive graphics, expandedexercises and computer project topics. An Instructor's Manual presenting detailed solutions to all theproblems in the book is available from the Wiley editorialdepartment.

Postharvest Handling
Postharvest Handling

Author: Nigel H. Banks

Publisher: Academic Press

Published: 2009-02-21

Total Pages: 637

ISBN-13: 0080920780

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Consideration of the interactions between decisions made at one point in the supply chain and its effects on the subsequent stages is the core concept of a systems approach. Postharvest Handling is unique in its application of this systems approach to the handling of fruits and vegetables, exploring multiple aspects of this important process through chapters written by experts from a variety of backgrounds.Newly updated and revised, this second edition includes coverage of the logistics of fresh produce from multiple perspectives, postharvest handing under varying weather conditions, quality control, changes in consumer eating habits and other factors key to successful postharvest handling.The ideal book for understanding the economic as well as physical impacts of postharvest handling decisions.Key Features:*Features contributions from leading experts providing a variety of perspectives*Updated with 12 new chapters*Focuses on application-based information for practical implementation*System approach is unique in the handling of fruits and vegetables

Converging Technologies for Improving Human Performance
Converging Technologies for Improving Human Performance

Author: Mihail C. Roco

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 477

ISBN-13: 9401703590

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M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.

Structural Health Monitoring
Structural Health Monitoring

Author: Daniel Balageas

Publisher: John Wiley & Sons

Published: 2010-01-05

Total Pages: 496

ISBN-13: 0470394404

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This book is organized around the various sensing techniques used to achieve structural health monitoring. Its main focus is on sensors, signal and data reduction methods and inverse techniques, which enable the identification of the physical parameters, affected by the presence of the damage, on which a diagnostic is established. Structural Health Monitoring is not oriented by the type of applications or linked to special classes of problems, but rather presents broader families of techniques: vibration and modal analysis; optical fibre sensing; acousto-ultrasonics, using piezoelectric transducers; and electric and electromagnetic techniques. Each chapter has been written by specialists in the subject area who possess a broad range of practical experience. The book will be accessible to students and those new to the field, but the exhaustive overview of present research and development, as well as the numerous references provided, also make it required reading for experienced researchers and engineers.