Models of Cellular Regulation
Models of Cellular Regulation

Author: Baltazar Aguda

Publisher: Oxford University Press

Published: 2008-07-31

Total Pages: 199

ISBN-13: 0198570910

DOWNLOAD EBOOK

This book illustrates the mechanisms and models linking the realms of molecular interactions and biological processes or functions. It addresses the need of mathematical modelers to learn how to formulate models of cellular processes and to understand how quantitative modeling can help sort through the complexities of molecular regulatory networks.

Calcium Entry Channels in Non-Excitable Cells
Calcium Entry Channels in Non-Excitable Cells

Author: Juliusz Ashot Kozak

Publisher: CRC Press

Published: 2017-07-14

Total Pages: 343

ISBN-13: 149875273X

DOWNLOAD EBOOK

Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Issues in Risk Assessment
Issues in Risk Assessment

Author: National Research Council

Publisher: National Academies Press

Published: 1993-02-01

Total Pages: 375

ISBN-13: 0309047862

DOWNLOAD EBOOK

The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

Models of Life
Models of Life

Author: Kim Sneppen

Publisher: Cambridge University Press

Published: 2014-10-02

Total Pages: 353

ISBN-13: 1107061903

DOWNLOAD EBOOK

An overview of current models of biological systems, reflecting the major advances that have been made over the past decade.

Cancer: Cell Structures, Carcinogens and Genomic Instability
Cancer: Cell Structures, Carcinogens and Genomic Instability

Author: Leon P. Bignold

Publisher: Springer Science & Business Media

Published: 2006

Total Pages: 398

ISBN-13: 9783764371562

DOWNLOAD EBOOK

Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related. The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals.

Probabilistic Boolean Networks
Probabilistic Boolean Networks

Author: Ilya Shmulevich

Publisher: SIAM

Published: 2010-01-21

Total Pages: 276

ISBN-13: 0898716926

DOWNLOAD EBOOK

The first comprehensive treatment of probabilistic Boolean networks, unifying different strands of current research and addressing emerging issues.

Biology for AP ® Courses
Biology for AP ® Courses

Author: Julianne Zedalis

Publisher:

Published: 2017-10-16

Total Pages: 1923

ISBN-13: 9781947172401

DOWNLOAD EBOOK

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Signaling Mechanisms Regulating T Cell Diversity and Function
Signaling Mechanisms Regulating T Cell Diversity and Function

Author: Jonathan Soboloff

Publisher: CRC Press

Published: 2017-03-27

Total Pages: 258

ISBN-13: 149870509X

DOWNLOAD EBOOK

T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

Single-Cell-Based Models in Biology and Medicine
Single-Cell-Based Models in Biology and Medicine

Author: Alexander Anderson

Publisher: Springer Science & Business Media

Published: 2007-08-08

Total Pages: 346

ISBN-13: 376438123X

DOWNLOAD EBOOK

Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.