Mip Synthesis, Characteristics and Analytical Application

Mip Synthesis, Characteristics and Analytical Application

Author:

Publisher: Elsevier

Published: 2019-08-09

Total Pages: 392

ISBN-13: 0444642676

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Mip Synthesis, Characteristics and Analytical Application, Volume 86 in the Comprehensive Analytical Chemistry series, highlights advances in the field, with this new volume presenting interesting chapters on synthesis and polymerization techniques of molecularly imprinted polymers, Solid phase extraction technique as a general field of application of molecularly imprinted polymer materials, Advanced artificially receptor- based sorbents for solid phase extraction using molecular imprinting technology: a new trend in food analysis, Application of molecularly imprinted polymers in microextraction and solventless extraction techniques, Magnetic molecularly imprinted microspheres – analytical approach, Surface Imprinted Micro- and Nanoparticles, and much more. Contains a valuable source of information on the wide spectrum of application fields of molecularly imprinted polymers as a green sorption medium Describes the application potential of currently molecular imprinting technologies, associated with the solid phase extraction techniques, magnetic imprinted microspheres, sorbents in mass spectrometry, and imprinted polymer electrochemical sensors


Molecularly Imprinted Polymer Composites

Molecularly Imprinted Polymer Composites

Author: Sooraj M.P.

Publisher: Woodhead Publishing

Published: 2020-12-01

Total Pages: 442

ISBN-13: 0128203854

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Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress. Includes information on molecular imprinted polymer composites and their potential for commercialization Discusses their synthesis, characterization and applications Analyzes the effect of incorporation of different nanostructures on the thermodynamic, kinetic and adsorption behavior of imprinted sorbents


Molecularly Imprinted Catalysts

Molecularly Imprinted Catalysts

Author: Songjun Li

Publisher: Elsevier

Published: 2015-09-30

Total Pages: 312

ISBN-13: 012801444X

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Molecularly Imprinted Catalysts: Principle, Synthesis, and Applications is the first book of its kind to provide an in-depth overview of molecularly imprinted catalysts and selective catalysis, including technical details, principles of selective catalysis, preparation processes, the catalytically active polymers themselves, and important progress made in this field. It serves as an important reference for scientists, students, and researchers who are working in the areas of molecular imprinting, catalysis, molecular recognition, materials science, biotechnology, and nanotechnology. Comprising a diverse group of experts from prestigious universities and industries across the world, the contributors to this book provide access to the latest knowledge and eye-catching achievements in the field, and an understanding of what progress has been made and to what extent it is being advanced in industry. The first book in the field on molecularly imprinted catalysts (MIPs) Provides a systematic background to selective catalysis, especially the basic concepts and key principles of the different MIP-based catalysts Features state-of-the art presentation of preparation methods and applications of MIPs Written by scientists from prestigious universities and industries across the world, and edited by veteran researchers in molecular imprinting and selective catalysis


Molecularly Imprinted Polymers

Molecularly Imprinted Polymers

Author: B. Sellergren

Publisher: Elsevier

Published: 2000-12-22

Total Pages: 583

ISBN-13: 0080536808

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This book is divided into 5 sections starting with an historic perspective and fundamental aspects on the synthesis and recognition by imprinted polymers. The second section contains 8 up-to-date overview chapters on current approaches to molecular and ion imprinting. This is followed by two chapters on new material morphologies and in the last two sections various analytical applications of imprinted polymers are given, with the last four chapters devoted to the promising field of imprinted polymers in chemical sensors.The authors of this volume have widely different backgrounds; mainly polymer chemistry, organic chemistry, biochemistry and analytical chemistry, which means that this book has an interdisciplinary character and should appeal to a broad audience.


Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Author: Zhaosheng Liu

Publisher: Springer Nature

Published: 2021-04-23

Total Pages: 218

ISBN-13: 9811602271

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This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives


Molecularly Imprinted Polymers in Biotechnology

Molecularly Imprinted Polymers in Biotechnology

Author: Bo Mattiasson

Publisher: Springer

Published: 2015-07-14

Total Pages: 237

ISBN-13: 3319207296

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Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity...), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bin Lu MIPs for binding macromolecules, by Kenneth J. Shea Solid phase extraction, by Ecevit Yilmaz Sensors, by Sergey A. Piletsky MIPs for catalysis and synthesis, by Marina Resmini Wastewater treatment, by Bo Mattiasson MIPs as tools for bioassays, biotransformation and drug delivery, by Meiping Zhao


Molecularly Imprinted Polymers

Molecularly Imprinted Polymers

Author: Faizatul Shimal Binti Mehamod

Publisher:

Published: 2011

Total Pages: 0

ISBN-13:

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Molecular imprinting, a technique for the preparation of polymeric materials that are capable of molecular recognition in various applications, is developing rapidly. In this study, work was directed towards the synthesis of novel molecularly imprinted polymers (MIPs) that enable high performance separations in analytical science and other fields. Furthermore, a new method of MIP synthesis, using controlled radical polymerisation, was explored, and a computational modelling method evaluated which enables the prediction of binding isotherms of MIPs in a qualitative manner prior to synthesis. The synthesis of ketamine imprinted polymers via a conventional approach is described. The overall aim of this study was to develop a new analytical method, Molecularly Imprinted Liquid Chromatography-Tandem Mass Spectrometry (MILC-MS/MS) for the detection of ketamine in hair. A key requirement was the production of ketamine imprinted polymer particulates in an appropriate physical format for the direct packing of the imprinted materials into chromatography columns, which were then hyphenated to a mass spectrometer. Several polymers were synthesised and their molecular recognition properties characterised using liquid chromatography techniques. A new analytical method for ketamine was set in place. iii The utility of controlled radical polymerisation in the preparation of MIPs was explored. The controlled radical polymerisation method of choice was reversible addition-fragmentation chain transfer (RAFT). The synthesis and use of a RAFT agent (CPDB) in MIP syntheses is described. It was discovered that polymers prepared via RAFT polymerisations enhanced the chromatographic performance of MIPs. Through a collaborative research study, an aim was to develop and evaluate a computational model for MIPs which predicted, in silico, the qualitative binding isotherms of a MIP. Real imprinted polymers were synthesised and their binding isotherms measured in order to test the validity of the predictive model. Pyridine imprinted and non-imprinted polymers were synthesised in monolithic form. There was good agreement between the predicted and experimental binding data.


Molecularly Imprinted Polymers

Molecularly Imprinted Polymers

Author: Antonio Martín-Esteban

Publisher: Humana

Published: 2021-08-20

Total Pages: 286

ISBN-13: 9781071616284

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This detailed volume explores molecularly imprinted polymers (MIPs), which have attracted great interest both in fundamental research and for practical applications due to their selective molecular recognition capabilities, extraordinary stability, and ease of preparation. Beginning with key laboratory protocols describing the different steps towards the synthesis of MIPs by different polymerization strategies, the volume continues by examining MIP use in sample preparation, their implementation on the development of sensors, as well as applications in other areas such catalysis and the use of bioinformatics and molecular modeling for MIPs design. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to the respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Molecularly Imprinted Polymers: Methods and Protocols serves as an ideal guide for researchers seeking to harness this very powerful approach for the preparation of molecular selective synthetic polymers.


Molecular Imprinting

Molecular Imprinting

Author: Lei Ye

Publisher: CRC Press

Published: 2013-09-26

Total Pages: 288

ISBN-13: 9814310999

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Molecular imprinting is one of the most efficient methods to fabricate functional polymer structures with pre-defined molecular recognition selectivity. Molecularly imprinted polymers (MIPs) have been used as antibody and enzyme mimics in a large number of applications. The outstanding stability and straightforward preparation make MIPs ideal substitutes for biologically derived molecular recognition materials, especially for development of affinity separation systems, chemical sensors and high selectivity catalysts. New MIP materials are being increasingly applied to solve challenging problems in environmental sciences, food safety control, biotechnology and medical diagnostics. Development in molecular imprinting research over the past decade has enabled tailor-designed molecular recognition sites to be created in synthetic materials with physical dimensions in the micro- and nano-regime. The new breakthroughs in MIP synthesis/fabrication have brought in many unprecedented functions of the micro- and nano-structured polymers. The aim of this review volume is to introduce to the readers the new developments in molecularly imprinted micro- and nano-structures, and the new applications that have been made possible with the new generation of imprinted materials.