Micro Implantable Neural Interfaces
Micro Implantable Neural Interfaces

Author: Dhondup Pemba

Publisher:

Published: 2013

Total Pages: 197

ISBN-13: 9781303001031

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Neuroprostheses allow the possibility of restoring lost sensory and motor function by directly interfacing with the nervous system. The multi-electrode array serves as a key component of the neural interface system that allows the recoding from and stimulation of the nervous system. Three neural electrode systems were developed in this work (1) Three dimensional bulk micromachined electrode array (2) Silicon-SU8 neural electrode with embedded microchannels for drug and growth factor delivery (3) A flexible SU-8 neural electrode with simultaneous fluidic delivery and electrical stimulation and recording capabilities. A three dimensional electrode array that depend only MEMS processes was developed to improve on several key fabrication steps involved in the manufacturing of the current state of the art intraneural electrodes which rely heavily on non-IC processes. A silicon and SU-8 neural probe with an embedded fluidic channel is developed to deliver growth factors and drugs that would mitigate the cellular responses that have limited the chronic implementation of current multielectrode arrays. In addition to delivering drugs and growth factors, a flexible SU-8 based neural probe with fluidic and electrical capabilities was developed to further extend the longevity of neural electrodes by reducing the tissue/electrode mechanical mismatch of traditional silicon based neural electrodes.

Implantable Bioelectronics
Implantable Bioelectronics

Author: Evgeny Katz

Publisher: John Wiley & Sons

Published: 2014-02-27

Total Pages: 566

ISBN-13: 3527673164

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Here the renowned editor Evgeny Katz has chosen contributions that cover a wide range of examples and issues in implantable bioelectronics, resulting in an excellent overview of the topic. The various implants covered include biosensoric and prosthetic devices, as well as neural and brain implants, while ethical issues, suitable materials, biocompatibility, and energy-harvesting devices are also discussed. A must-have for both newcomers and established researchers in this interdisciplinary field that connects scientists from chemistry, material science, biology, medicine, and electrical engineering.

Neural Interface Engineering
Neural Interface Engineering

Author: Liang Guo

Publisher: Springer Nature

Published: 2020-05-04

Total Pages: 436

ISBN-13: 3030418545

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This book provides a comprehensive reference to major neural interfacing technologies used to transmit signals between the physical world and the nervous system for repairing, restoring and even augmenting body functions. The authors discuss the classic approaches for neural interfacing, the major challenges encountered, and recent, emerging techniques to mitigate these challenges for better chronic performances. Readers will benefit from this book’s unprecedented scope and depth of coverage on the technology of neural interfaces, the most critical component in any type of neural prostheses. Provides comprehensive coverage of major neural interfacing technologies; Reviews and discusses both classic and latest, emerging topics; Includes classification of technologies to provide an easy grasp of research and trends in the field.

Neural Microelectrodes: Design and Applications
Neural Microelectrodes: Design and Applications

Author: Stuart Cogan

Publisher:

Published: 2019

Total Pages: 1

ISBN-13: 9783039213207

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Neural electrodes enable the recording and stimulation of bioelectrical activity in the nervous system. This technology provides neuroscientists with the means to probe the functionality of neural circuitry in both health and disease. In addition, neural electrodes can deliver therapeutic stimulation for the relief of debilitating symptoms associated with neurological disorders such as Parkinson's disease and may serve as the basis for the restoration of sensory perception through peripheral nerve and brain regions after disease or injury. Lastly, microscale neural electrodes recording signals associated with volitional movement in paralyzed individuals can be decoded for controlling external devices and prosthetic limbs or driving the stimulation of paralyzed muscles for functional movements. In spite of the promise of neural electrodes for a range of applications, chronic performance remains a goal for long-term basic science studies, as well as clinical applications. New perspectives and opportunities from fields including tissue biomechanics, materials science, and biological mechanisms of inflammation and neurodegeneration are critical to advances in neural electrode technology. This Special Issue will address the state-of-the-art knowledge and emerging opportunities for the development and demonstration of advanced neural electrodes.

Implantable Neural Prostheses 1
Implantable Neural Prostheses 1

Author: David Zhou

Publisher: Springer Science & Business Media

Published: 2009-06-10

Total Pages: 391

ISBN-13: 0387772618

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Significant progress has been made in the development of neural prostheses to restore human functions and improve the quality of human life. Biomedical engineers and neuroscientists around the world are working to improve design and performance of existing devices and to develop novel devices for artificial vision, artificial limbs, and brain–machine interfaces. This book, Implantable Neural Prostheses 1: Devices and Applications,ispart one of a two-book series and describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices and their applications. Devices covered include sensory prosthetic devices, such as visual implants, cochlear implants, auditory midbrain implants, and spinal cord stimulators. Motor prosthetic devices, such as deep brain stimulators, Bion microstimu- tors, the brain control and sensing interface, and cardiac electro-stimulation devices are also included. Progress in magnetic stimulation that may offer a non-invasive approach to prosthetic devices is introduced. Regulatory approval of implantable medical devices in the United States and Europe is also discussed.

Implantable Neural Prostheses 2
Implantable Neural Prostheses 2

Author: David Zhou

Publisher: Springer Science & Business Media

Published: 2010-07-10

Total Pages: 371

ISBN-13: 0387981209

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Signi?cant progress has been made in the development of neural prostheses for restoration of human functions and improvement of the quality of life. Biomedical engineers and neuroscientists around the world are working to improve the design and performance of existing devices and to develop novel devices for arti?cial vision, arti?cial limbs, and brain-machine interfaces. This book, Implantable Neural Prostheses 2: Techniques and Engineering Approaches, is part two of a two-volume sequence that describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices. The techniques covered include biocompatibility and biostability, hermetic packaging, electrochemical techniques for neural stimulation applications, novel electrode materials and testing, thin-?lm ?exible microelectrode arrays, in situ char- terization of microelectrode arrays, chip-size thin-?lm device encapsulation, microchip-embedded capacitors and microelectronics for recording, stimulation, and wireless telemetry. The design process in the development of medical devices is also discussed. Advances in biomedical engineering, microfabrication technology, and neu- science have led to improved medical-device designs and novel functions. However, many challenges remain. This book focuses on the engineering approaches, R&D advances, and technical challenges of medical implants from an engineering p- spective. We are grateful to leading researchers from academic institutes, national laboratories, as well as design engineers and professionals from the medical device industry who have contributed to the book. Part one of this series covers designs of implantable neural prosthetic devices and their clinical applications.

Optical Neural Interfaces
Optical Neural Interfaces

Author: Massimo De Vittorio

Publisher:

Published: 2019

Total Pages: 0

ISBN-13:

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Implantable Biomedical Microsystems
Implantable Biomedical Microsystems

Author: Swarup Bhunia

Publisher: Elsevier

Published: 2015-01-28

Total Pages: 337

ISBN-13: 0323261906

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Research and innovation in areas such as circuits, microsystems, packaging, biocompatibility, miniaturization, power supplies, remote control, reliability, and lifespan are leading to a rapid increase in the range of devices and corresponding applications in the field of wearable and implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the health conditions of the human body. This book provides comprehensive coverage of the fundamental design principles and validation for implantable microsystems, as well as several major application areas. Each component in an implantable device is described in details, and major case studies demonstrate how these systems can be optimized for specific design objectives. The case studies include applications of implantable neural signal processors, brain-machine interface (BMI) systems intended for both data recording and treatment, neural prosthesis, bladder pressure monitoring for treating urinary incontinence, implantable imaging devices for early detection and diagnosis of diseases as well as electrical conduction block of peripheral nerve for chronic pain management. Implantable Biomedical Microsystems is the first comprehensive coverage of bioimplantable system design providing an invaluable information source for researchers in Biomedical, Electrical, Computer, Systems, and Mechanical Engineering as well as engineers involved in design and development of wearable and implantable bioelectronic devices and, more generally, teams working on low-power microsystems and their corresponding wireless energy and data links. - First time comprehensive coverage of system-level and component-level design and engineering aspects for implantable microsystems. - Provides insight into a wide range of proven applications and application specific design trade-offs of bioimplantable systems, including several major case studies - Enables Engineers involved in development of implantable electronic systems to optimize applications for specific design objectives.