Methodology for Genetic Studies of Twins and Families
Methodology for Genetic Studies of Twins and Families

Author: M. Neale

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 503

ISBN-13: 9401580189

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Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

Methodology for Genetic Studies of Twins and Families
Methodology for Genetic Studies of Twins and Families

Author: Michael Neale

Publisher: Springer Science & Business Media

Published: 1992-07-31

Total Pages: 536

ISBN-13: 9780792318743

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Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

Methodology for Genetic Studies of Twins and Families
Methodology for Genetic Studies of Twins and Families

Author: Michael Neale

Publisher: Springer

Published: 2014-03-14

Total Pages: 496

ISBN-13: 9789401580199

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Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

The Oxford Handbook of Quantitative Methods, Vol. 2: Statistical Analysis
The Oxford Handbook of Quantitative Methods, Vol. 2: Statistical Analysis

Author: Todd D. Little

Publisher: Oxford University Press

Published: 2013-02-01

Total Pages: 784

ISBN-13: 0199934908

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Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.

Handbook of Behavior Genetics
Handbook of Behavior Genetics

Author: Yong-Kyu Kim

Publisher: Springer Science & Business Media

Published: 2009-03-25

Total Pages: 557

ISBN-13: 0387767274

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This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

Twin Research for Everyone
Twin Research for Everyone

Author: Adam D. Tarnoki

Publisher: Elsevier

Published: 2022-08-22

Total Pages: 738

ISBN-13: 0128215143

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Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions. Offers unique insights into twinning rates, mechanisms and factors surrounding twinship Provides clear instruction on both basic and advanced twin research methods and study design Features leading international experts in twin biology, genetics, health and psychology Examines findings from recent twin studies across a broad array of health and behavioral studies

The Neurobiological Basis of Suicide
The Neurobiological Basis of Suicide

Author: Yogesh Dwivedi

Publisher: CRC Press

Published: 2012-06-25

Total Pages: 485

ISBN-13: 143983881X

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With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Twin Studies:
Twin Studies:

Author: Grant C Townsend

Publisher: University of Adelaide Press

Published: 2015-10-08

Total Pages: 218

ISBN-13: 1925261158

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This volume is about an ongoing long-term research initiative led by researchers from the School of Dentistry at the University of Adelaide. The aim of this book is to provide an overview of the studies of the teeth and faces of Australian twins and their families that have extended over more than thirty years.

Twin and Family Studies of Epigenetics
Twin and Family Studies of Epigenetics

Author: Shuai Li

Publisher: Academic Press

Published: 2021-08-19

Total Pages: 376

ISBN-13: 0128209526

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Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. - Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties - Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders - Features chapter contributions from a wide range of international researchers in the field

The Trouble with Twin Studies
The Trouble with Twin Studies

Author: Jay Joseph

Publisher: Routledge

Published: 2014-11-20

Total Pages: 334

ISBN-13: 1317605918

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The Trouble with Twin Studies questions popular genetic explanations of human behavioral differences based upon the existing body of twin research. Psychologist Jay Joseph outlines the fallacies of twin studies in the context of the ongoing decades-long failure to discover genes for human behavioral differences, including IQ, personality, and the major psychiatric disorders. This volume critically examines twin research, with a special emphasis on reared-apart twin studies, and incorporates new and updated perspectives, analyses, arguments, and evidence.