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Covering the most important developments in meta-analysis from 1990 to 2004, this text presents new patterns in research findings as well as updated information on existing topics.
Publication bias is the tendency to decide to publish a study based on the results of the study, rather than on the basis of its theoretical or methodological quality. It can arise from selective publication of favorable results, or of statistically significant results. This threatens the validity of conclusions drawn from reviews of published scientific research. Meta-analysis is now used in numerous scientific disciplines, summarizing quantitative evidence from multiple studies. If the literature being synthesised has been affected by publication bias, this in turn biases the meta-analytic results, potentially producing overstated conclusions. Publication Bias in Meta-Analysis examines the different types of publication bias, and presents the methods for estimating and reducing publication bias, or eliminating it altogether. Written by leading experts, adopting a practical and multidisciplinary approach. Provides comprehensive coverage of the topic including: Different types of publication bias, Mechanisms that may induce them, Empirical evidence for their existence, Statistical methods to address them, Ways in which they can be avoided. Features worked examples and common data sets throughout. Explains and compares all available software used for analysing and reducing publication bias. Accompanied by a website featuring software, data sets and further material. Publication Bias in Meta-Analysis adopts an inter-disciplinary approach and will make an excellent reference volume for any researchers and graduate students who conduct systematic reviews or meta-analyses. University and medical libraries, as well as pharmaceutical companies and government regulatory agencies, will also find this invaluable.
Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. The various approaches are presented within a general unified framework. Meta-analysis techniques are described in detail, from their theoretical development through to practical implementation. Each topic discussed is supported by detailed worked examples. A comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis. Fully documented programs using standard statistical procedures in SAS are available on the Web. Ideally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.
This remarkable text raises the analysis of data in health sciences and policy to new heights of refinement and applicability by introducing cutting-edge meta-analysis strategies while reviewing more commonly used techniques. Each chapter builds on sound principles, develops methodologies to solve statistical problems, and presents concrete applications used by experienced medical practitioners and health policymakers. Written by more than 30 celebrated international experts, Meta-Analysis in Medicine and Health Policy employs copious examples and pictorial presentations to teach and reinforce biostatistical techniques more effectively and poses numerous open questions of medical and health policy research.
Illustrates the value of combining findings from specific high-quality primary research studies into a cohesive summary that better defines what the science of drug abuse prevention offers to guide future program decisionmaking. Presents a current overview of the efficacy of drug abuse prevention programs (DAPG) and related measurement systems. Defines the techniques employed in meta-analysis of DAPG. Provides guidance in the application of research findings from meta-analysis. Discusses key technical procedures that should be considered in conducting future meta-analysis of drug abuse prevention research.
Meta-heuristics have developed dramatically since their inception in the early 1980s. They have had widespread success in attacking a variety of practical and difficult combinatorial optimization problems. These families of approaches include, but are not limited to greedy random adaptive search procedures, genetic algorithms, problem-space search, neural networks, simulated annealing, tabu search, threshold algorithms, and their hybrids. They incorporate concepts based on biological evolution, intelligent problem solving, mathematical and physical sciences, nervous systems, and statistical mechanics. Since the 1980s, a great deal of effort has been invested in the field of combinatorial optimization theory in which heuristic algorithms have become an important area of research and applications. This volume is drawn from the first conference on Meta-Heuristics and contains 41 papers on the state-of-the-art in heuristic theory and applications. The book treats the following meta-heuristics and applications: Genetic Algorithms, Simulated Annealing, Tabu Search, Networks & Graphs, Scheduling and Control, TSP, and Vehicle Routing Problems. It represents research from the fields of Operations Research, Management Science, Artificial Intelligence and Computer Science.
Praised in the first edition for the clarity of his general framework for conceptualizing meta-analysis, Rosenthal's revised edition covers the latest techniques in the field, such as a new effect size indicator for one size data, a new coefficient of robustness of replication, new procedures for combining and comparing effect sizes for multiple dependent variables, and new data on the magnitude of the problem of incomplete retrieval (the file drawer problem).
