Clarke's Analysis of Drugs and Poisons

Clarke's Analysis of Drugs and Poisons

Author: A. C. Moffat

Publisher:

Published: 2004

Total Pages: 680

ISBN-13:

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This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.


Pharma

Pharma

Author: Gerald Posner

Publisher: Simon and Schuster

Published: 2020-03-10

Total Pages: 816

ISBN-13: 1501152041

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Award-winning journalist and New York Times bestselling author Gerald Posner reveals the heroes and villains of the trillion-dollar-a-year pharmaceutical industry and delivers “a withering and encyclopedic indictment of a drug industry that often seems to prioritize profits over patients (The New York Times Book Review). Pharmaceutical breakthroughs such as anti­biotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on pre­scription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. “Gerald’s dogged reporting, sets Pharma apart from all books on this subject” (The Washington Standard) as we are introduced to brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company exec­utives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers’ rise to power—revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. “Explosively, even addictively, readable” (Booklist, starred review), Pharma reveals how and why American drug com­panies have put earnings ahead of patients.


Bottle of Lies

Bottle of Lies

Author: Katherine Eban

Publisher: HarperCollins

Published: 2020-06-23

Total Pages: 523

ISBN-13: 0063054108

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A NEW YORK TIMES BESTSELLER * New York Times Notable Book * Best Book of the Year: New York Public Library, Kirkus Reviews, Science Friday With a new postscript by the author From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticals Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.


Medicine and Poisonous Pharma

Medicine and Poisonous Pharma

Author: Rui Alexandre Gabirro

Publisher: Order of the Good News

Published: 2020-04-04

Total Pages: 556

ISBN-13: 191605093X

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“In a considerable proportion of diseases, it would fare as well, or better, with patients, in the actual condition of the medical art, as more generally practised, if all remedies, at least all active remedies, especially drugs, were abandoned." - Sir John Forbes, MD "Medicines succeed best when there is a tendency to get well." - Gull “The Truth Is Often More Helpful Than Drugs”. - Lord Dawson of Penn, Physician to H.M. the King, London Hospital in “B.M.J.”, 9 July 1921. “Drugs don't make you well, they make you worse! Health has a name, is called: Food, Medicine has a name, is called: Poisonous Drugs. Synthetic Pharmaceutical drugs are liver toxic, synthetic drugs accelerate the body into premature death. People are thus being poisoned to death, by what they call Medicine.” - Rui Gabirro “Spoiler Warning” This book contains information that is not taught at medical school. The Purpose of this Book “The present work is written for the double purpose of correcting error, and imparting truth. Its purpose is to state facts by which their pretensions may be judged.” - Dr. Frederick Hollick, MD in “Neuropathy or The True Principles of the Art of Healing the Sick”, 1847.


Healing with Poisons

Healing with Poisons

Author: Yan Liu

Publisher: University of Washington Press

Published: 2021-06-22

Total Pages: 278

ISBN-13: 0295749016

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Open access edition: DOI 10.6069/9780295749013 At first glance, medicine and poison might seem to be opposites. But in China’s formative era of pharmacy (200–800 CE), poisons were strategically employed as healing agents to cure everything from abdominal pain to epidemic disease. Healing with Poisons explores the ways physicians, religious figures, court officials, and laypersons used toxic substances to both relieve acute illnesses and enhance life. It illustrates how the Chinese concept of du—a word carrying a core meaning of “potency”—led practitioners to devise a variety of methods to transform dangerous poisons into effective medicines. Recounting scandals and controversies involving poisons from the Era of Division to the Tang, historian Yan Liu considers how the concept of du was central to how the people of medieval China perceived both their bodies and the body politic. He also examines the wide range of toxic minerals, plants, and animal products used in classical Chinese pharmacy, including everything from the herb aconite to the popular recreational drug Five-Stone Powder. By recovering alternative modes of understanding wellness and the body’s interaction with foreign substances, this study cautions against arbitrary classifications and exemplifies the importance of paying attention to the technical, political, and cultural conditions in which substances become truly meaningful. Healing with Poisons is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem) and the generous support of the University of Buffalo.


Bad Pharma

Bad Pharma

Author: Ben Goldacre

Publisher: Macmillan

Published: 2014-04

Total Pages: 479

ISBN-13: 0865478066

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Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc.


Forging a Poison Prevention and Control System

Forging a Poison Prevention and Control System

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2004-09-16

Total Pages: 369

ISBN-13: 0309091942

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Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control "system" is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete "system" that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century.


Mechanisms of Drug Toxicity

Mechanisms of Drug Toxicity

Author: H. Rašková

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 113

ISBN-13: 1483157202

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Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.


Drugs and Poisons in Humans

Drugs and Poisons in Humans

Author: Osamu Suzuki

Publisher: Springer Science & Business Media

Published: 2006-01-16

Total Pages: 653

ISBN-13: 3540275797

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Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists Includes source of chemicals needed for the experiments Texts are composed by 67 experts in analyzing the respective compounds Clear and uniform structure of chapters for ease of reading The text is illustrated by many diagrams and tables


Deadly Medicines and Organised Crime

Deadly Medicines and Organised Crime

Author: Peter Gotzsche

Publisher: CRC Press

Published: 2019-08-21

Total Pages: 251

ISBN-13: 1908911123

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PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the pharmaceutical industries and their charade of fraudulent behaviour, both in research and marketing where the morally repugnant disregard for human lives is the norm. He convincingly draws close co