Mammalian Cytogenetics and Related Problems in Radiobiology
Mammalian Cytogenetics and Related Problems in Radiobiology

Author: C. Pavan

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 448

ISBN-13: 1483185265

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Mammalian Cytogenetics and Related Problems in Radiobiology covers the proceedings of a symposium held in Sao Paulo and Rio de Janeiro, Brazil in October 1962. The book focuses on the processes, methodologies, and approaches involved in mammalian cytogenetics and radiobiology. The selection first offers information on the nutrition and metabolism of cultured mammalian cells, blood technique and human chromosomes, and DNA replication in human chromosomes. Discussions focus on replication of heterochromatin in the human male; difficulties involved in the study of DNA synthesis in human chromosomes; and perspectives for future research. The text then ponders on the progress in the utilization of cell culture techniques for studies in mammalian and human somatic cell genetics and modification of radiation effects in the Ehrlich ascites tumor by oxygen or sodium azide. The manuscript examines experimental studies on mammalian chromosome aberrations, chromosome breakage in vitro, and survival of human cells in tissue culture after irradiation with densely and sparsely ionizing radiation. The text then elaborates on the observations on the morphology and behavior of normal human chromosomes, human pachytene chromosomes, and abnormalities of autosomes. The selection is a vital reference for readers interested in mammalian cytogenetics and radiobiology.

Radiation Cytogenetics
Radiation Cytogenetics

Author: Takamitsu A. Kato

Publisher: Humana

Published: 2019-07-04

Total Pages: 138

ISBN-13: 9781493994304

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This book comprises a collection of chapters describing topics from traditional radiation cytogenetic analysis methods to the modern fluorescence based-analysis and high throughput automatic analysis methods. Cytogenetic analysis is important not only in order to understand radiation-induced DNA damage in cells, but it is also a standard biological method to estimate human radiation exposure in the radiation accidents. Therefore, we prepared a series of chapters not only covering biological aspects but also exploring radiation physics and radiation protection. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Radiation Cytogenetics: Methods and Protocols serves both novices working on their first experiments as well as experienced researchers searching for tried-and-true techniques to adapt for their own laboratory.

Human and Mammalian Cytogenetics
Human and Mammalian Cytogenetics

Author: Tao-Chiuh Hsu

Publisher: Springer

Published: 1979-06-18

Total Pages: 204

ISBN-13:

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The history of science is mostly written retrospec tively, a generation or two after the actual events being discussed. Science historians are now analyzing and evaluating the origins of evolutionary and genetical theory in the nineteenth century and a sort of "Darwin industry" seems to have grown up. A history of mammalian cytogenetics by one of the main participants is, hence, a very welcome change, since it has a vividness, an immediacy and a personal flavor which these scholarly tomes and the official biog raphies of scientists mostly lack. The life of the author, Chinese-born, T. C. Hsu, has been a romantic and color ful one, and he is himself a unique personality, so that his book is a very unusual blend of reminiscences, history of his special field (which has transformed human genetics) and wise comments on the mistakes made along the way. The best qualities of a very fine Chinese mind have contributed to Dr. Hsu's career, including this book. Those qualities (which seem to me especially Chinese) include a kind of transparent honesty, a very direct em pirical approach to problems and superb technical ability.