Solid-Liquid Filtration and Separation Technology

Solid-Liquid Filtration and Separation Technology

Author: Albert Rushton

Publisher: John Wiley & Sons

Published: 2008-07-11

Total Pages: 542

ISBN-13: 3527614966

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A valuable presentation of theoretical and practical information in the area of liquid-solid filtration. The development of theoretical models is highlighted with practical design data and problem-related examples. Modern trends, e.g., membrane systems, are reported together with the fundamental aspects of particulate technology. The increasing interest in pollution control and environmental protection provides an expansive market for this book. Chemical engineers, chemists, physicists, water treatment/sewage engineers, civil engineers and all those concerned with filtration and pollution will find this book of tremendous value and practical use.


Downstream Processing of Proteins

Downstream Processing of Proteins

Author: Mohamed A. Desai

Publisher: Springer Science & Business Media

Published: 2008-02-05

Total Pages: 233

ISBN-13: 1592590276

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Considerable effort and time is allocated to introducing cell culture and fermentation technology to undergraduate students in academia, generally through a range of courses in industrial biotechnology and related disciplines. Similarly, a large number of textbooks are available to describe the appli- tions of these technologies in industry. However, there has been a general lack of appreciation of the significant developments in downstream processing and isolation technology, the need for which is largely driven by the stringent re- latory requirements for purity and quality of injectable biopharmaceuticals. This is particularly reflected by the general absence of coverage of this s- ject in many biotechnology and related courses in educational institutions. For a considerable while I have felt that there is increasing need for an introductory text to various aspects of downstream processing, particularly with respect to the needs of the biopharmaceutical and biotechnology ind- try. Although there are numerous texts that cover various aspects of protein purification techniques in isolation, there is a need for a work that covers the broad range of isolation technology in an industrial setting. It is anticipated that Downstream Processing of Proteins: Methods and Protocols will play a small part in filling this gap and thus prove a useful contribution to the field. It is also designed to encourage educational strategists to broaden the coverage of these topics in industrial biotechnology courses by including accounts of this important and rapidly developing element of the industrial process.


Isolation and Purification of Proteins

Isolation and Purification of Proteins

Author: Rajni Hatti-Kaul

Publisher: CRC Press

Published: 2003-02-05

Total Pages: 653

ISBN-13: 0824747593

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This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.